| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| ACORN BIOVENTURES, L.P. | 8% | +18.6% | $11,859,557 | +$1,988,442 | 3,940,052 | +20.1% | Anders Hove | 31 Dec 2024 |
| BlackRock, Inc. | 5.6% | $8,366,151 | 2,779,452 | BlackRock, Inc. | 31 Mar 2025 | |||
| MILLENNIUM MANAGEMENT LLC | 3.9% | $5,701,319 | 1,894,126 | Millennium Management LLC | 31 Dec 2024 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 34,367,867 | $182,467,133 | +$11,618,135 | $5.31 | 131 |
| 2025 Q2 | 32,782,327 | $112,437,236 | +$8,596,760 | $3.43 | 121 |
| 2025 Q1 | 30,413,709 | $90,020,693 | +$2,952,602 | $2.96 | 116 |
| 2024 Q4 | 29,394,127 | $89,648,308 | -$7,801,084 | $3.05 | 111 |
| 2024 Q3 | 29,741,414 | $75,860,432 | -$5,784,759 | $2.55 | 100 |
| 2024 Q2 | 30,964,332 | $100,942,686 | -$1,236,662 | $3.26 | 98 |
| 2024 Q1 | 29,743,016 | $157,668,204 | +$17,052,475 | $5.3 | 93 |
| 2023 Q4 | 26,608,129 | $115,214,198 | +$4,767,738 | $4.33 | 82 |
| 2023 Q3 | 25,704,166 | $67,598,924 | -$2,428,856 | $2.63 | 67 |
| 2023 Q2 | 26,576,438 | $93,807,644 | -$4,382,380 | $3.53 | 67 |
| 2023 Q1 | 27,855,345 | $86,065,002 | -$527,663 | $3.09 | 77 |
| 2022 Q4 | 27,496,427 | $116,318,396 | -$138,759 | $4.23 | 86 |
| 2022 Q3 | 27,643,484 | $65,508,451 | -$1,989,453 | $2.37 | 71 |
| 2022 Q2 | 27,896,143 | $79,494,556 | -$4,139,901 | $2.85 | 77 |
| 2022 Q1 | 29,904,506 | $86,071,643 | -$477,483 | $2.88 | 95 |
| 2021 Q4 | 30,286,741 | $92,179,926 | -$39,504,988 | $3.04 | 96 |
| 2021 Q3 | 32,161,600 | $225,498,183 | -$28,665,006 | $7.01 | 112 |
| 2021 Q2 | 34,758,681 | $319,233,355 | -$17,282,962 | $9.18 | 118 |
| 2021 Q1 | 36,622,682 | $355,897,814 | +$13,747,740 | $9.72 | 117 |
| 2020 Q4 | 35,303,327 | $362,460,750 | -$9,270,334 | $10.26 | 120 |
| 2020 Q3 | 38,674,035 | $390,198,466 | +$12,930,607 | $10.09 | 128 |
| 2020 Q2 | 35,087,132 | $365,869,787 | -$6,707,284 | $10.43 | 124 |
| 2020 Q1 | 36,622,300 | $308,895,684 | +$43,630,089 | $8.44 | 121 |
| 2019 Q4 | 31,346,607 | $274,240,276 | -$64,624,795 | $8.75 | 129 |
| 2019 Q3 | 36,566,451 | $393,738,047 | +$16,141,553 | $10.77 | 138 |
| 2019 Q2 | 34,765,202 | $441,844,355 | -$103,904,681 | $12.71 | 132 |
| 2019 Q1 | 34,161,633 | $1,323,863,060 | +$17,647,411 | $38.79 | 156 |
| 2018 Q4 | 35,195,489 | $716,303,054 | -$227,829,815 | $20.35 | 137 |
| 2018 Q3 | 35,649,697 | $1,634,461,087 | -$26,392,843 | $45.85 | 154 |
| 2018 Q2 | 35,935,120 | $2,125,191,869 | -$1,056,901 | $59.15 | 169 |
| 2018 Q1 | 35,574,353 | $2,419,811,616 | -$81,238,705 | $68.05 | 168 |
| 2017 Q4 | 36,157,207 | $3,573,656,170 | -$112,228,539 | $98.85 | 194 |
| 2017 Q3 | 36,681,359 | $4,391,736,256 | +$169,794,588 | $119.75 | 170 |
| 2017 Q2 | 35,525,549 | $3,104,620,640 | +$57,539,772 | $87.4 | 152 |
| 2017 Q1 | 37,964,211 | $1,412,435,790 | +$191,118,200 | $37.2 | 135 |
| 2016 Q4 | 34,931,958 | $1,072,410,439 | +$72,943,477 | $30.7 | 128 |
| 2016 Q3 | 29,992,904 | $2,010,275,475 | +$5,538,941 | $67.05 | 145 |
| 2016 Q2 | 31,810,369 | $947,699,404 | +$39,640,223 | $29.79 | 107 |
| 2016 Q1 | 30,412,423 | $892,904,817 | -$134,999,214 | $29.37 | 114 |
| 2015 Q4 | 32,269,617 | $2,529,775,949 | +$177,573,758 | $78.4 | 131 |
| 2015 Q3 | 30,151,475 | $2,271,836,092 | -$40,738,025 | $75.36 | 159 |
| 2015 Q2 | 30,442,694 | $3,553,611,040 | -$40,063,235 | $116.75 | 193 |
| 2015 Q1 | 29,120,599 | $6,873,292,525 | +$477,852,182 | $236.11 | 194 |
| 2014 Q4 | 27,148,671 | $5,140,326,488 | +$68,524,432 | $189.27 | 183 |
| 2014 Q3 | 26,680,747 | $6,365,417,896 | +$471,513,554 | $238.57 | 182 |
| 2014 Q2 | 25,372,332 | $1,674,353,490 | -$43,122,202 | $66 | 132 |
| 2014 Q1 | 25,068,536 | $2,610,636,453 | +$107,147,987 | $104.14 | 130 |