Praxis Precision Medicines, Inc. - Common Stock (PRAX)

CUSIP: 74006W207

Q2 2025 13F Holders as of 30 Jun 2025

Type / Class
Equity / Common Stock
Shares outstanding
27,884,538
Total 13F shares
24,151,627
Share change
+794,872
Total reported value
$1,015,573,040
Put/Call ratio
56%
Price per share
$42.05
Number of holders
141
Value change
+$43,479,424
Number of buys
89
Number of sells
64

Quarterly Holders Quick Answers

What is CUSIP 74006W207?
CUSIP 74006W207 identifies PRAX - Praxis Precision Medicines, Inc. - Common Stock in SEC institutional holdings data.

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Top shareholders of PRAX - Praxis Precision Medicines, Inc. - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
Clarus Lifesciences III, L.P.
3/4/5
10%+ Owner
class O/S missing
4,894,109
$123,282,606 12 May 2021
Cormorant Asset Management, LP
13F
Company
6.3%
1,745,000
$66,083,150 31 Mar 2025
13F
ADAGE CAPITAL PARTNERS GP, L.L.C.
13F
Company
6.2%
1,742,758
$65,998,245 31 Mar 2025
13F
JANUS HENDERSON GROUP PLC
13F
Company
5.4%
1,506,436
$58,349,110 31 Mar 2025
13F
BlackRock, Inc.
13F
Company
5.1%
1,416,935
$53,659,329 31 Mar 2025
13F
MORGAN STANLEY
13F
Company
4.4%
1,213,669
$45,961,681 31 Mar 2025
13F
Soleus Capital Management, L.P.
13F
Company
4.1%
1,139,740
$43,161,954 31 Mar 2025
13F
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
3.9%
1,095,725
$41,497,000 31 Mar 2025
13F
VANGUARD GROUP INC
13F
Company
3.9%
1,087,020
$41,165,448 31 Mar 2025
13F
Soleus Capital Master Fund, L.P.
13D/G
4.6%
966,740
$40,651,514 -$2,144,555 30 Jun 2025
Venrock Healthcare Capital Partners III, L.P.
13D/G
4.9%
1,016,497
$37,813,688 -$6,466,960 31 Mar 2025
VR Adviser, LLC
13F
Company
3.6%
989,985
$37,490,732 31 Mar 2025
13F
PERCEPTIVE ADVISORS LLC
13F
Company
3.5%
980,894
$37,146,456 31 Mar 2025
13F
Capital Research Global Investors
13F 13D/G
Company
4.2%
from 13D/G
853,746
$32,331,361 31 Mar 2025
STATE STREET CORP
13F
Company
2.6%
737,039
$27,911,667 31 Mar 2025
13F
DEERFIELD MANAGEMENT COMPANY, L.P.
13F
Company
2.2%
619,931
$23,476,787 31 Mar 2025
13F
Assenagon Asset Management S.A.
13F
Company
1.8%
507,400
$19,215,238 31 Mar 2025
13F
DRIEHAUS CAPITAL MANAGEMENT LLC
13F
Company
1.7%
481,598
$18,238,116 31 Mar 2025
13F
BANK OF AMERICA CORP /DE/
13F
Company
1.7%
460,707
$17,446,976 31 Mar 2025
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
1.5%
418,016
$15,833,923 31 Mar 2025
13F
BALYASNY ASSET MANAGEMENT L.P.
13F
Company
1.4%
403,003
$15,261,724 31 Mar 2025
13F
CIBC Asset Management Inc
13F
Company
1.4%
388,759
$14,722,303 31 Mar 2025
13F
Point72 Asset Management, L.P.
13F
Company
1.2%
333,534
$12,630,933 31 Mar 2025
13F
BAKER BROS. ADVISORS LP
13F
Company
1.2%
331,533
$12,555,155 31 Mar 2025
13F
FRANKLIN RESOURCES INC
13F
Company
1.1%
314,127
$11,895,990 31 Mar 2025
13F
Verition Fund Management LLC
13F
Company
0.72%
199,657
$7,561,011 31 Mar 2025
13F
UBS Group AG
13F
Company
0.69%
192,909
$7,305,463 31 Mar 2025
13F
Velan Capital Investment Management LP
13F
Company
0.66%
185,000
$7,005,950 31 Mar 2025
13F
GOLDMAN SACHS GROUP INC
13F
Company
0.64%
177,264
$6,712,988 31 Mar 2025
13F
Woodline Partners LP
13F
Company
0.63%
175,727
$6,654,781 31 Mar 2025
13F
5AM Venture Management, LLC
13F
Company
0.61%
170,000
$6,437,900 31 Mar 2025
13F
SILVERARC CAPITAL MANAGEMENT, LLC
13F
Company
0.6%
166,074
$6,289,222 31 Mar 2025
13F
NORTHERN TRUST CORP
13F
Company
0.59%
165,183
$6,255,480 31 Mar 2025
13F
PFM Health Sciences, LP
13F
Company
0.58%
160,866
$6,091,995 31 Mar 2025
13F
Sofinnova Investments, Inc.
13F
Company
0.57%
157,640
$5,969,827 31 Mar 2025
13F
Alyeska Investment Group, L.P.
13F
Company
0.54%
150,000
$5,680,500 31 Mar 2025
13F
Ikarian Capital, LLC
13F
Company
0.52%
145,502
$5,510,161 31 Mar 2025
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.51%
141,080
$5,342,700 31 Mar 2025
13F
SPHERA FUNDS MANAGEMENT LTD.
13F
Company
0.5%
140,660
$5,326,794 31 Mar 2025
13F
Walleye Capital LLC
13F
Company
0.47%
131,756
$4,989,600 31 Mar 2025
13F
Sio Capital Management, LLC
13F
Company
0.4%
112,500
$4,260,375 31 Mar 2025
13F
Ally Bridge Group (NY) LLC
13F
Company
0.34%
95,582
$3,619,690 31 Mar 2025
13F
Aberdeen Group plc
13F
Company
0.32%
87,903
$3,328,887 31 Mar 2025
13F
ACUTA CAPITAL PARTNERS, LLC
13F
Company
0.31%
87,141
$3,300,030 31 Mar 2025
13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC
13F
Company
0.31%
87,081
$3,297,757 31 Mar 2025
13F
Tri Locum Partners LP
13F
Company
0.3%
83,659
$3,168,166 31 Mar 2025
13F
Pictet Asset Management Holding SA
13F
Company
0.28%
78,588
$2,976,128 31 Mar 2025
13F
First Turn Management, LLC
13F
Company
0.26%
71,775
$2,718,119 31 Mar 2025
13F
MILLENNIUM MANAGEMENT LLC
13F
Company
0.25%
69,181
$2,619,884 31 Mar 2025
13F
72 Investment Holdings, LLC
13F
Company
0.24%
65,933
$2,496,883 31 Mar 2025
13F

Institutional Holders of Praxis Precision Medicines, Inc. - Common Stock (PRAX) as of Q2 2025

As of 30 Jun 2025, Praxis Precision Medicines, Inc. - Common Stock (PRAX) was held by 141 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 24,151,627 shares. The largest 10 holders included JANUS HENDERSON GROUP PLC, ADAGE CAPITAL PARTNERS GP, L.L.C., Cormorant Asset Management, LP, BlackRock, Inc., PRICE T ROWE ASSOCIATES INC /MD/, MORGAN STANLEY, VANGUARD GROUP INC, Soleus Capital Management, L.P., Point72 Asset Management, L.P., and PERCEPTIVE ADVISORS LLC. This page lists 141 institutional shareholders reporting positions in this security for the Q2 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q2 2025 vs Q1 2025 Across Filers

Q1 2025 holders
147
Q2 2025 holders
141
Holder diff
-6
Investor Q1 2025 Shares Q2 2025 Shares Share Diff Share Chg % Q1 2025 Value $ Q2 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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