Praxis Precision Medicines, Inc. - Common Stock (PRAX)
CUSIP: 74006W207
Q3 2025 13F Holders as of 30 Sep 2025
- Type / Class
- Equity / Common Stock
- Shares outstanding
- 25,726,377
- Total 13F shares
- 24,666,145
- Share change
- +512,170
- Total reported value
- $1,307,300,657
- Put/Call ratio
- 75%
- Price per share
- $53.00
- Number of holders
- 150
- Value change
- +$38,898,368
- Number of buys
- 86
- Number of sells
- 64
Quarterly Holders Quick Answers
What is CUSIP 74006W207?
CUSIP 74006W207 identifies PRAX - Praxis Precision Medicines, Inc. - Common Stock in SEC institutional holdings data.
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Recent filing periods for CUSIP 74006W207:
Top shareholders of PRAX - Praxis Precision Medicines, Inc. - Common Stock (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC |
13D/G
13F
|
Company |
12%
|
2,763,859
|
$146,484,527 | +$12,214,062 | 30 Sep 2025 | |
| Clarus Lifesciences III, L.P. |
3/4/5
|
10%+ Owner |
—
class O/S missing
|
4,894,109
|
$123,282,606 | — | 12 May 2021 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
7.7%
|
1,974,585
|
$83,031,299 | — | 30 Jun 2025 | |
| Cormorant Asset Management, LP |
13F
13D/G
|
Company |
4%
from 13D/G
|
1,625,000
|
$68,331,250 | — | 30 Jun 2025 | |
| BlackRock, Inc. |
13F
|
Company |
6.2%
|
1,590,128
|
$66,864,882 | — | 30 Jun 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
13D/G
|
Company · T. Rowe Price Associates, Inc. |
4.8%
from 13D/G
|
1,473,075
|
$61,944,000 | — | 30 Jun 2025 | |
| MORGAN STANLEY |
13F
13D/G
|
Company |
2.9%
from 13D/G
|
1,226,339
|
$51,567,583 | — | 30 Jun 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
4.7%
|
1,215,644
|
$51,117,830 | — | 30 Jun 2025 | |
| Soleus Capital Master Fund, L.P. |
13D/G
|
— |
4.6%
|
966,740
|
$40,651,514 | -$2,144,555 | 30 Jun 2025 | |
| Soleus Capital Management, L.P. |
13F
|
Company |
3.8%
|
966,740
|
$40,651,417 | — | 30 Jun 2025 | |
| Point72 Asset Management, L.P. |
13F
|
Company |
3.7%
|
954,075
|
$40,118,854 | — | 30 Jun 2025 | |
| Venrock Healthcare Capital Partners III, L.P. |
13D/G
|
— |
4.9%
|
1,016,497
|
$37,813,688 | -$6,466,960 | 31 Mar 2025 | |
| Capital Research Global Investors |
13D/G
|
— |
4.2%
|
853,746
|
$31,759,351 | $0 | 31 Mar 2025 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
2.9%
|
752,921
|
$31,660,328 | — | 30 Jun 2025 | |
| STATE STREET CORP |
13F
|
Company |
2.7%
|
698,093
|
$29,354,811 | — | 30 Jun 2025 | |
| BAKER BROS. ADVISORS LP |
13F
|
Company |
2.7%
|
689,488
|
$28,992,970 | — | 30 Jun 2025 | |
| DEERFIELD MANAGEMENT COMPANY, L.P. |
13F
|
Company |
2.7%
|
686,931
|
$28,885,449 | — | 30 Jun 2025 | |
| Assenagon Asset Management S.A. |
13F
|
Company |
2.3%
|
604,298
|
$25,410,731 | — | 30 Jun 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
2.1%
|
530,988
|
$22,328,045 | — | 30 Jun 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
1.8%
|
453,403
|
$19,065,595 | — | 30 Jun 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.8%
|
451,731
|
$18,997,366 | — | 30 Jun 2025 | |
| CIBC Asset Management Inc |
13F
|
Company |
1.5%
|
388,759
|
$16,347,316 | — | 30 Jun 2025 | |
| BALYASNY ASSET MANAGEMENT L.P. |
13F
|
Company |
1.4%
|
369,254
|
$15,527,131 | — | 30 Jun 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
1.2%
|
314,150
|
$13,210,007 | — | 30 Jun 2025 | |
| Ikarian Capital, LLC |
13F
|
Company |
1.1%
|
276,950
|
$11,645,747 | — | 30 Jun 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.88%
|
225,992
|
$9,502,964 | — | 30 Jun 2025 | |
| Logos Global Management LP |
13F
|
Company |
0.87%
|
225,000
|
$9,461,250 | — | 30 Jun 2025 | |
| Aberdeen Group plc |
13F
|
Company |
0.83%
|
214,056
|
$9,001,055 | — | 30 Jun 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.83%
|
213,712
|
$8,986,589 | — | 30 Jun 2025 | |
| Tri Locum Partners LP |
13F
|
Company |
0.76%
|
195,432
|
$8,217,916 | — | 30 Jun 2025 | |
| 5AM Venture Management, LLC |
13F
|
Company |
0.66%
|
170,000
|
$7,148,500 | — | 30 Jun 2025 | |
| Vivo Capital, LLC |
13F
|
Company |
0.65%
|
167,600
|
$7,047,580 | — | 30 Jun 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.59%
|
152,444
|
$6,410,270 | — | 30 Jun 2025 | |
| Velan Capital Investment Management LP |
13F
|
Company |
0.58%
|
149,334
|
$6,279,495 | — | 30 Jun 2025 | |
| Alyeska Investment Group, L.P. |
13F
|
Company |
0.49%
|
125,000
|
$5,256,250 | — | 30 Jun 2025 | |
| Verition Fund Management LLC |
13F
|
Company |
0.46%
|
118,482
|
$4,982,168 | — | 30 Jun 2025 | |
| BOOTHBAY FUND MANAGEMENT, LLC |
13F
|
Company |
0.46%
|
118,121
|
$4,966,988 | — | 30 Jun 2025 | |
| SPHERA FUNDS MANAGEMENT LTD. |
13F
|
Company |
0.43%
|
109,757
|
$4,615,282 | — | 30 Jun 2025 | |
| Schonfeld Strategic Advisors LLC |
13F
|
Company |
0.39%
|
100,702
|
$4,234,515 | — | 30 Jun 2025 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
13F
|
Company |
0.38%
|
96,945
|
$4,076,538 | — | 30 Jun 2025 | |
| BARCLAYS PLC |
13F
|
Company |
0.34%
|
88,724
|
$3,730,844 | — | 30 Jun 2025 | |
| UBS Group AG |
13F
|
Company |
0.34%
|
86,534
|
$3,638,755 | — | 30 Jun 2025 | |
| PFM Health Sciences, LP |
13F
|
Company |
0.33%
|
84,713
|
$3,562,182 | — | 30 Jun 2025 | |
| Ally Bridge Group (NY) LLC |
13F
|
Company |
0.31%
|
80,880
|
$3,401,004 | — | 30 Jun 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.31%
|
79,143
|
$3,328,490 | — | 30 Jun 2025 | |
| ACUTA CAPITAL PARTNERS, LLC |
13F
|
Company |
0.29%
|
74,087
|
$3,115,358 | — | 30 Jun 2025 | |
| KENNEDY CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.27%
|
70,445
|
$2,962,212 | — | 30 Jun 2025 | |
| HighVista Strategies LLC |
13F
|
Company |
0.26%
|
67,288
|
$2,829,460 | — | 30 Jun 2025 | |
| 72 Investment Holdings, LLC |
13F
|
Company |
0.26%
|
65,933
|
$2,772,483 | — | 30 Jun 2025 | |
| TD ASSET MANAGEMENT INC |
13F
|
Company |
0.25%
|
63,938
|
$2,688,593 | — | 30 Jun 2025 |
Institutional Holders of Praxis Precision Medicines, Inc. - Common Stock (PRAX) as of Q3 2025
As of 30 Sep 2025,
Praxis Precision Medicines, Inc. - Common Stock (PRAX) was held by
150 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
24,666,145 shares.
The largest 10 holders included
JANUS HENDERSON GROUP PLC, ADAGE CAPITAL PARTNERS GP, L.L.C., BlackRock, Inc., PERCEPTIVE ADVISORS LLC, Point72 Asset Management, L.P., VANGUARD GROUP INC, PRICE T ROWE ASSOCIATES INC /MD/, Cormorant Asset Management, LP, STATE STREET CORP, and Soleus Capital Management, L.P..
This page lists
150
institutional shareholders reporting positions in this security
for the Q3 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q3 2025 vs Q2 2025 Across Filers
Q2 2025 holders
141
Q3 2025 holders
150
Holder diff
9
| Investor | Q2 2025 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q2 2025 Value $ | Q3 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.