Praxis Precision Medicines, Inc. - Common Stock, par value $0.0001 per share (PRAX)

Q: What does CUSIP 74006W207 represent in this 13F holders report?

CUSIP 74006W207 is the security identifier for PRAX - Praxis Precision Medicines, Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held PRAX - Praxis Precision Medicines, Inc. - Common Stock, par value $0.0001 per share in Q3 2025?

150 institutional investors reported PRAX - Praxis Precision Medicines, Inc. - Common Stock, par value $0.0001 per share for Q3 2025. Use the holders table for investor-level position and value details.

CUSIP: 74006W207

Q3 2025 13F Holders as of 30 Sep 2025

Security type / class: Equity / Common Stock, par value $0.0001 per share
Total 13F shares: 24,666,145
Total 13F value: $1,307,300,657
Share change: +512,170
Put/Call ratio: 75%
SEC-reported price per share: $53.00
Number of holders: 150
Value change: +$38,898,368
Number of buys: 86
Number of sells: 64
Shares outstanding: 27,828,540

Security key

74006W207

Report period

Q3 2025

Institutions

150

Top holders

PRAX full security history Ownership snapshot Full 13F holder table Newer quarter: Q2 2026 Praxis Precision Medicines, Inc. SEC filings Praxis Precision Medicines, Inc. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 74006W207

Newer quarter: Q2 2026

Recent filing periods:

Q2 2026

Ownership snapshot

Top reported holders of PRAX - Praxis Precision Medicines, Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

Janus Henderson Group Ltd.

Disclosed value leader

Janus Henderson Group Ltd.

Comparable rows

15/15

Latest evidence

30 Sep 2025

13D/G 13F Lead comparable stake: 12% 13D/G row: Janus Henderson Group Ltd. Showing 1-6 of 15 holder rows.

Quick read

Janus Henderson Group Ltd. leads the comparable SEC ownership view at 12%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Janus Henderson Group Ltd.'s linked filing trail.

Comparable ownership Top 5

Janus Henderson Group Ltd. 12%

Venrock Healthcare Capital Partne... 4.9%

PRICE T ROWE ASSOCIATES INC /MD/ 4.8%

Soleus Capital Master Fund, L.P. 4.6%

Capital Research Global Investors 4.2%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
Janus Henderson Group Ltd.	13D/G 13F JANUS HENDERSON GROUP PLC · Company 13D/G 13F	12%	$146,484,527 2,763,859 shares	+$12,214,062	30 Sep 2025
Venrock Healthcare Capital Partners III, L.P.	13D/G 13D/G	4.9%	$37,813,688 1,016,497 shares	-$6,466,960	31 Mar 2025
PRICE T ROWE ASSOCIATES INC /MD/	13F 13D/G Company · T. Rowe Price Associates, Inc. 13F 13D/G	4.8% from 13D/G	$61,944,000 1,473,075 shares	—	30 Jun 2025
Soleus Capital Master Fund, L.P.	13D/G 13D/G	4.6%	$40,651,514 966,740 shares	-$2,144,555	30 Jun 2025
Capital Research Global Investors	13D/G 13D/G	4.2%	$31,759,351 853,746 shares	$0	31 Mar 2025
Cormorant Asset Management, LP	13F 13D/G Company 13F 13D/G	4% from 13D/G	$68,331,250 1,625,000 shares	—	30 Jun 2025

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q3 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

150

24,666,145

Rows available

150

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q3 2025 vs Q2 2025 Across Filers

Q2 2025 holders

141

Q3 2025 holders

150

Holder diff

Investor	Q2 2025 Shares	Q3 2025 Shares	Share Diff	Share Chg %	Q2 2025 value	Q3 2025 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend