Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)

Q: What does CUSIP 48576U106 represent in this 13F holders report?

CUSIP 48576U106 is the security identifier for KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in Q2 2020?

155 institutional investors reported KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share for Q2 2020. Use the holders table for investor-level position and value details.

CUSIP: 48576U106

Q2 2020 13F Holders as of 30 Jun 2020

Type / Class: Equity / Common Stock, par value $0.0001 per share
Shares outstanding: 22,242,217
Total 13F shares: 69,738,739
Share change: +2,442,866
Total reported value: $1,320,807,090
Put/Call ratio: 49%
Price per share: $18.94
Number of holders: 155
Value change: +$45,201,421
Number of buys: 108
Number of sells: 53

Quarterly Holders Quick Answers

What is CUSIP 48576U106?
CUSIP 48576U106 identifies KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in SEC institutional holdings data.

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Newer quarter: Q3 2020
Previous quarter: Q1 2020

Recent filing periods for CUSIP 48576U106:

Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024

Top shareholders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
Consonance Capital Management LP	13F	Company	32%	7,180,700	$137,941,000	—	31 Mar 2020	13F
Avoro Capital Advisors LLC	13F	Company	31%	7,000,000	$134,470,000	—	31 Mar 2020	13F
BlackRock Finance, Inc.	13F	Company	24%	5,326,002	$102,313,000	—	31 Mar 2020	13F
Palo Alto Investors LP	13F	Company	19%	4,299,901	$82,601,000	—	31 Mar 2020	13F
ADAGE CAPITAL PARTNERS GP, L.L.C.	13F	Company	17%	3,723,532	$71,529,000	—	31 Mar 2020	13F
JANUS HENDERSON GROUP PLC	13F	Company	15%	3,252,828	$62,487,000	—	31 Mar 2020	13F
VANGUARD GROUP INC	13F	Company	15%	3,248,459	$62,403,000	—	31 Mar 2020	13F
STATE STREET CORP	13F	Company	15%	3,247,487	$62,384,000	—	31 Mar 2020	13F
D. E. Shaw & Co., Inc.	13F	Company	11%	2,403,780	$46,177,000	—	31 Mar 2020	13F
ALKEON CAPITAL MANAGEMENT LLC	13F	Company	9.7%	2,164,900	$41,587,000	—	31 Mar 2020	13F
FRONTIER CAPITAL MANAGEMENT CO LLC	13F	Company	8.3%	1,839,440	$35,336,000	—	31 Mar 2020	13F
CITADEL ADVISORS LLC	13F	Company	6.8%	1,506,303	$28,936,000	—	31 Mar 2020	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	6.3%	1,398,646	$26,868,000	—	31 Mar 2020	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	6.3%	1,394,739	$26,793,000	—	31 Mar 2020	13F
FARALLON CAPITAL MANAGEMENT LLC	13F	Company	6%	1,335,000	$25,645,000	—	31 Mar 2020	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	4.9%	1,089,102	$20,923,000	—	31 Mar 2020	13F
EMERALD ADVISERS, LLC	13F	Company	4.7%	1,045,548	$20,085,000	—	31 Mar 2020	13F
GOLDMAN SACHS GROUP INC	13F	Company	4.3%	959,251	$18,427,000	—	31 Mar 2020	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	4.2%	933,327	$17,928,000	—	31 Mar 2020	13F
Hood River Capital Management LLC	13F	Company	4%	888,284	$17,064,000	—	31 Mar 2020	13F
EMERALD MUTUAL FUND ADVISERS TRUST	13F	Company	3.9%	865,725	$16,631,000	—	31 Mar 2020	13F
S.c.a. Candriam	13F	Individual	3.8%	845,366	$15,842,000	—	31 Mar 2020	13F
FMR LLC	13F	Company	3.5%	769,298	$14,778,000	—	31 Mar 2020	13F
NORTHERN TRUST CORP	13F	Company	3.4%	765,307	$14,701,000	—	31 Mar 2020	13F
TWO SIGMA ADVISERS, LP	13F	Company	3.3%	732,100	$14,064,000	—	31 Mar 2020	13F
Elk Creek Partners, LLC	13F	Company	3.1%	699,951	$13,446,000	—	31 Mar 2020	13F
RICE HALL JAMES & ASSOCIATES, LLC	13F	Company	2.7%	596,745	$11,463,000	—	31 Mar 2020	13F
Fairmount Funds Management LLC	13F	Company	2.5%	562,351	$10,803,000	—	31 Mar 2020	13F
SPHERA FUNDS MANAGEMENT LTD.	13F	Company	2.5%	550,000	$10,566,000	—	31 Mar 2020	13F
RENAISSANCE TECHNOLOGIES LLC	13F	Company	2.4%	534,000	$10,258,000	—	31 Mar 2020	13F
Atom Investors LP	13F	Company	2.1%	472,182	$9,071,000	—	31 Mar 2020	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	2%	437,622	$8,407,000	—	31 Mar 2020	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	1.7%	386,138	$7,418,000	—	31 Mar 2020	13F
MACQUARIE GROUP LTD	13F	Company	1.7%	380,000	$7,300,000	—	31 Mar 2020	13F
Bank of New York Mellon Corp	13F	Company	1.5%	327,439	$6,291,000	—	31 Mar 2020	13F
Nuveen Asset Management, LLC	13F	Company	1.3%	284,219	$5,460,000	—	31 Mar 2020	13F
JPMORGAN CHASE & CO	13F	Company	1.2%	257,725	$4,951,000	—	31 Mar 2020	13F
Parkman Healthcare Partners LLC	13F	Company	0.97%	215,802	$4,146,000	—	31 Mar 2020	13F
Informed Momentum Co LLC	13F	Company	0.8%	178,844	$3,436,000	—	31 Mar 2020	13F
PARAMETRIC PORTFOLIO ASSOCIATES LLC	13F	Company	0.71%	158,310	$3,041,000	—	31 Mar 2020	13F
DEUTSCHE BANK AG\	13F	Company	0.68%	150,825	$2,897,000	—	31 Mar 2020	13F
Birchview Capital, LP	13F	Company	0.67%	148,000	$2,843,000	—	31 Mar 2020	13F
QS Investors, LLC	13F	Company	0.66%	146,300	$2,811,000	—	31 Mar 2020	13F
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	13F	Company	0.62%	138,144	$2,654,000	—	31 Mar 2020	13F
Global IMC LLC	13F	Company	0.61%	136,402	$2,620,000	—	31 Mar 2020	13F
Lisanti Capital Growth, LLC	13F	Company	0.6%	134,082	$2,576,000	—	31 Mar 2020	13F
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	13F	Company	0.6%	132,897	$2,553,000	—	31 Mar 2020	13F
RHUMBLINE ADVISERS	13F	Company	0.57%	126,277	$2,426,000	—	31 Mar 2020	13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F	Company	0.49%	109,956	$2,112,000	—	31 Mar 2020	13F
Integral Health Asset Management, LLC	13F	Company	0.45%	100,000	$1,921,000	—	31 Mar 2020	13F

Institutional Holders of Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) as of Q2 2020

As of 30 Jun 2020, Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) was held by 155 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 69,738,739 shares. The largest 10 holders included Avoro Capital Advisors LLC, Consonance Capital Management LP, BlackRock Inc., STATE STREET CORP, Palo Alto Investors LP, VANGUARD GROUP INC, ADAGE CAPITAL PARTNERS GP, L.L.C., D. E. Shaw & Co., Inc., FRONTIER CAPITAL MANAGEMENT CO LLC, and ALKEON CAPITAL MANAGEMENT LLC. This page lists 155 institutional shareholders reporting positions in this security for the Q2 2020 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q2 2020 vs Q1 2020 Across Filers

Q1 2020 holders

135

Q2 2020 holders

155

Holder diff

Investor	Q1 2020 Shares	Q2 2020 Shares	Share Diff	Share Chg %	Q1 2020 Value $	Q2 2020 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.