Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)

Q: What does CUSIP 48576U106 represent in this 13F holders report?

CUSIP 48576U106 is the security identifier for KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in Q1 2020?

135 institutional investors reported KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share for Q1 2020. Use the holders table for investor-level position and value details.

CUSIP: 48576U106

Q1 2020 13F Holders as of 31 Mar 2020

Security type / class: Equity / Common Stock, par value $0.0001 per share
Total 13F shares: 67,992,711
Total 13F value: $1,305,743,291
Share change: +11,296,204
Put/Call ratio: 133%
SEC-reported price per share: $19.21
Number of holders: 135
Value change: +$217,084,502
Number of buys: 80
Number of sells: 72
Shares outstanding: 22,658,403

Security key

48576U106

Report period

Q1 2020

Institutions

135

Top holders

KPTI full security history Ownership snapshot Full 13F holder table Newer quarter: Q3 2025 Karyopharm Therapeutics Inc. SEC filings Karyopharm Therapeutics Inc. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 48576U106

Newer quarter: Q3 2025

Recent filing periods:

Q1 2026 Q4 2025 Q3 2025

Ownership snapshot

Top reported holders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

Consonance Capital Manage...

Disclosed value leader

Consonance Capital Manage...

Comparable rows

15/15

Latest evidence

31 Dec 2019

13F Lead comparable stake: 27% Showing 1-6 of 15 holder rows.

Quick read

Consonance Capital Management LP leads the comparable SEC ownership view at 27%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Consonance Capital Management LP's linked filing trail.

Comparable ownership Top 5

Consonance Capital Management LP 27%

Avoro Capital Advisors LLC 26%

BlackRock Finance, Inc. 21%

Palo Alto Investors LP 20%

ADAGE CAPITAL PARTNERS GP, L.L.C. 17%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
Consonance Capital Management LP	13F Company 13F	27%	$117,463,000 6,127,434 shares	—	31 Dec 2019
Avoro Capital Advisors LLC	13F Company 13F	26%	$113,103,000 5,900,000 shares	—	31 Dec 2019
BlackRock Finance, Inc.	13F Company 13F	21%	$91,419,000 4,768,926 shares	—	31 Dec 2019
Palo Alto Investors LP	13F Company 13F	20%	$88,086,000 4,595,001 shares	—	31 Dec 2019
ADAGE CAPITAL PARTNERS GP, L.L.C.	13F Company 13F	17%	$72,597,000 3,787,000 shares	—	31 Dec 2019
STATE STREET CORP	13F Company 13F	14%	$61,888,000 3,228,366 shares	—	31 Dec 2019

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q1 2020

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

135

67,992,711

Rows available

135

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q1 2020 vs Q4 2025 Across Filers

Q4 2025 holders

Q1 2020 holders

135

Holder diff

135

Investor	Q4 2025 Shares	Q1 2020 Shares	Share Diff	Share Chg %	Q4 2025 value	Q1 2020 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend