Security key
48576U106
Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)
CUSIP: 48576U106
Q2 2025 13F Holders as of 30 Jun 2025
- Type / Class
- Equity / Common Stock, par value $0.0001 per share
- Shares outstanding
- 22,658,403
- Total 13F shares
- 27,985
- Share change
- -324,032
- Total reported value
- $120,615
- Price per share
- $4.31
- Number of holders
- 1
- Value change
- -$1,211,880
- Number of sells
- 1
Report period
Q2 2025
Institutions
1
Top holders
1
KPTI full security history
Newer quarter: Q3 2025
Previous quarter: Q1 2025
Karyopharm Therapeutics Inc. SEC filings
Karyopharm Therapeutics Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 48576U106
Recent filing periods:
Top shareholders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC |
13F
|
Company |
2.7%
|
510,294
|
$1,908,499 | — | 31 Mar 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
2.2%
|
421,322
|
$1,575,744 | — | 31 Mar 2025 | |
| Palo Alto Investors LP |
13F
|
Company |
1.4%
|
324,032
|
$1,211,880 | — | 31 Mar 2025 | |
| Eversept Partners, LP |
13F
|
Company |
1.4%
|
257,154
|
$961,756 | — | 31 Mar 2025 | |
| BlackRock, Inc. |
13F
|
Company |
1.3%
|
242,742
|
$907,858 | — | 31 Mar 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
1.1%
|
206,909
|
$773,840 | — | 31 Mar 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.9%
|
170,790
|
$638,755 | — | 31 Mar 2025 | |
| Catalio Capital Management, LP |
13F
|
Company |
0.82%
|
155,622
|
$582,026 | — | 31 Mar 2025 | |
| T. Rowe Price Investment Management, Inc. |
13F
|
Company |
0.73%
|
139,646
|
$523,000 | — | 31 Mar 2025 | |
| Avidity Partners Management LP |
13F
|
Company |
0.71%
|
134,566
|
$503,277 | — | 31 Mar 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.7%
|
132,908
|
$497,075 | — | 31 Mar 2025 | |
| MARSHALL WACE, LLP |
13F
|
Company |
0.68%
|
128,451
|
$480,407 | — | 31 Mar 2025 | |
| C WorldWide Group Holding A/S |
13F
|
Company |
0.53%
|
100,000
|
$374,000 | — | 31 Mar 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.52%
|
99,640
|
$372,743 | — | 31 Mar 2025 | |
| UBS Group AG |
13F
|
Company |
0.49%
|
93,612
|
$350,109 | — | 31 Mar 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.45%
|
85,410
|
$319,433 | — | 31 Mar 2025 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
0.32%
|
61,214
|
$228,940 | — | 31 Mar 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.29%
|
55,367
|
$207,073 | — | 31 Mar 2025 | |
| Altium Capital Management LLC |
13F
|
Company |
0.26%
|
49,333
|
$184,505 | — | 31 Mar 2025 | |
| STATE STREET CORP |
13F
|
Company |
0.16%
|
29,495
|
$110,311 | — | 31 Mar 2025 | |
| BNP PARIBAS FINANCIAL MARKETS |
13F
|
Company |
0.15%
|
28,961
|
$108,314 | — | 31 Mar 2025 | |
| Ikarian Capital, LLC |
13F
|
Company |
0.14%
|
27,257
|
$101,941 | — | 31 Mar 2025 | |
| Shay Capital LLC |
13F
|
Company |
0.13%
|
25,417
|
$95,060 | — | 31 Mar 2025 | |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
13F
|
Company |
0.12%
|
23,640
|
$88,414 | — | 31 Mar 2025 | |
| Birchview Capital, LP |
13F
|
Company |
0.12%
|
27,985
|
$104,664 | — | 31 Mar 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.1%
|
18,910
|
$70,724 | — | 31 Mar 2025 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.06%
|
11,548
|
$43,190 | — | 31 Mar 2025 | |
| JANE STREET GROUP, LLC |
13F
|
Company |
0.06%
|
11,420
|
$42,711 | — | 31 Mar 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.06%
|
11,086
|
$41,461 | — | 31 Mar 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.05%
|
10,423
|
$38,982 | — | 31 Mar 2025 | |
| Leonteq Securities AG |
13F
|
Company |
0.05%
|
10,000
|
$37,300 | — | 31 Mar 2025 | |
| CITIGROUP INC |
13F
|
Company |
0.04%
|
7,044
|
$26,345 | — | 31 Mar 2025 | |
| BARCLAYS PLC |
13F
|
Company |
0.03%
|
5,333
|
$19,945 | — | 31 Mar 2025 | |
| TD Waterhouse Canada Inc. |
13F
|
Company |
0.02%
|
3,203
|
$11,275 | — | 31 Mar 2025 | |
| ROYAL BANK OF CANADA |
13F
|
Company |
0.01%
|
1,426
|
$5,000 | — | 31 Mar 2025 | |
| FMR LLC |
13F
|
Company |
0%
|
527
|
$1,971 | — | 31 Mar 2025 | |
| OSAIC HOLDINGS, INC. |
13F
|
Company |
0%
|
346
|
$1,293 | — | 31 Mar 2025 | |
| COLDSTREAM CAPITAL MANAGEMENT INC |
13F
|
Company |
0%
|
331
|
$1,238 | — | 31 Mar 2025 | |
| Quent Capital, LLC |
13F
|
Company |
0%
|
231
|
$864 | — | 31 Mar 2025 | |
| VSM Wealth Advisory, LLC |
13F
|
Company |
0%
|
133
|
$497 | — | 31 Mar 2025 | |
| MB, LEVIS & ASSOCIATES, LLC |
13F
|
Company |
0%
|
100
|
$374 | — | 31 Mar 2025 | |
| HARBOUR INVESTMENTS, INC. |
13F
|
Company |
0%
|
85
|
$318 | — | 31 Mar 2025 | |
| SBI Securities Co., Ltd. |
13F
|
Company |
0%
|
74
|
$277 | — | 31 Mar 2025 | |
| Activest Wealth Management |
13F
|
Company |
0%
|
66
|
$247 | — | 31 Mar 2025 | |
| Allworth Financial LP |
13F
|
Company |
0%
|
32
|
$192 | — | 31 Mar 2025 | |
| Bruce G. Allen Investments, LLC |
13F
|
Company |
0%
|
22
|
$82 | — | 31 Mar 2025 | |
| CIBC Private Wealth Group LLC |
13F
|
Company |
0%
|
3
|
$12 | — | 31 Mar 2025 | |
| West Branch Capital LLC |
13F
|
Company |
0%
|
3
|
$12 | — | 31 Mar 2025 | |
| DANSKE BANK A/S |
13F
|
Company |
0%
|
3
|
$11 | — | 31 Mar 2025 | |
| Sharon Shacham |
3/4/5
|
Chief Scientific Officer |
—
mixed-class rows
|
1,761,888
mixed-class rows
|
$1,370,948 | — | 29 Mar 2022 |
Institutional Holders of Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) as of Q2 2025
As of 30 Jun 2025,
Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) was held by
1 institutional
shareholder
that filed Form 13F with the SEC.
Together, they reported ownership of
27,985 shares.
The largest 1 holders included
Birchview Capital, LP.
This page lists
1
institutional shareholders reporting positions in this security
for the Q2 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q2 2025 vs Q1 2025 Across Filers
Q1 2025 holders
2
Q2 2025 holders
1
Holder diff
-1
| Investor | Q1 2025 Shares | Q2 2025 Shares | Share Diff | Share Chg % | Q1 2025 Value $ | Q2 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.