Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)

Q: What does CUSIP 48576U106 represent in this 13F holders report?

CUSIP 48576U106 is the security identifier for KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in Q1 2017?

79 institutional investors reported KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share for Q1 2017. Use the holders table for investor-level position and value details.

CUSIP: 48576U106

Q1 2017 13F Holders as of 31 Mar 2017

Type / Class: Equity / Common Stock, par value $0.0001 per share
Shares outstanding: 22,242,217
Total 13F shares: 26,846,913
Share change: +3,428,941
Total reported value: $344,713,183
Put/Call ratio: 79%
Price per share: $12.84
Number of holders: 79
Value change: +$45,322,035
Number of buys: 43
Number of sells: 35

Quarterly Holders Quick Answers

What is CUSIP 48576U106?
CUSIP 48576U106 identifies KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in SEC institutional holdings data.

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Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q2 2017
Previous quarter: Q4 2016

Recent filing periods for CUSIP 48576U106:

Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024

Top shareholders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	26%	5,726,416	$53,828,000	—	31 Dec 2016	13F
FMR LLC	13F	Company	21%	4,730,131	$44,463,000	—	31 Dec 2016	13F
FRANKLIN RESOURCES INC	13F	Company	15%	3,231,201	$30,374,000	—	31 Dec 2016	13F
Palo Alto Investors LP	13F	Company	14%	3,200,396	$30,084,000	—	31 Dec 2016	13F
BlackRock Fund Advisors	13F	Company	6.2%	1,376,355	$12,938,000	—	31 Dec 2016	13F
VANGUARD GROUP INC	13F	Company	5.1%	1,126,669	$10,591,000	—	31 Dec 2016	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	3.2%	711,156	$6,685,000	—	31 Dec 2016	13F
BlackRock Institutional Trust Company, N.A.	13F	Company	2.5%	556,383	$5,230,000	—	31 Dec 2016	13F
Tekla Capital Management LLC	13F	Company	2.2%	500,324	$4,703,000	—	31 Dec 2016	13F
JPMORGAN CHASE & CO	13F	Company	1.9%	412,376	$3,877,000	—	31 Dec 2016	13F
STATE STREET CORP	13F	Company	1.8%	406,103	$3,820,000	—	31 Dec 2016	13F
S.c.a. Candriam	13F	Individual	1.8%	390,000	$3,666,000	—	31 Dec 2016	13F
NORTHERN TRUST CORP	13F	Company	1.3%	290,405	$2,730,000	—	31 Dec 2016	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	1.2%	261,055	$2,454,000	—	31 Dec 2016	13F
BAKER BROS. ADVISORS LP	13F	Company	0.98%	216,990	$2,040,000	—	31 Dec 2016	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.7%	156,493	$1,471,000	—	31 Dec 2016	13F
DEUTSCHE BANK AG\	13F	Company	0.53%	118,465	$1,112,000	—	31 Dec 2016	13F
Bank of New York Mellon Corp	13F	Company	0.5%	112,286	$1,056,000	—	31 Dec 2016	13F
TFS CAPITAL LLC	13F	Company	0.47%	105,040	$987,000	—	31 Dec 2016	13F
BlackRock Investment Management, LLC	13F	Company	0.47%	103,508	$973,000	—	31 Dec 2016	13F
MORGAN STANLEY	13F	Company	0.46%	102,556	$964,000	—	31 Dec 2016	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.46%	101,702	$956,000	—	31 Dec 2016	13F
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	13F	Company	0.39%	87,030	$818,000	—	31 Dec 2016	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.37%	82,752	$778,000	—	31 Dec 2016	13F
UNITED SERVICES AUTOMOBILE ASSOCIATION	13F	Company	0.34%	75,900	$713,000	—	31 Dec 2016	13F
TIAA CREF INVESTMENT MANAGEMENT LLC	13F	Company	0.32%	70,557	$663,000	—	31 Dec 2016	13F
SECOR Capital Advisors, LP	13F	Company	0.3%	66,484	$625,000	—	31 Dec 2016	13F
RHUMBLINE ADVISERS	13F	Company	0.29%	64,802	$609,000	—	31 Dec 2016	13F
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	13F	Company	0.25%	55,844	$525,000	—	31 Dec 2016	13F
ESSEX INVESTMENT MANAGEMENT CO LLC	13F	Company	0.25%	55,793	$524,000	—	31 Dec 2016	13F
Piermont Capital Management Inc.	13F	Company	0.23%	51,080	$480,000	—	31 Dec 2016	13F
CITADEL ADVISORS LLC	13F	Company	0.21%	45,984	$432,000	—	31 Dec 2016	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.21%	45,819	$431,000	—	31 Dec 2016	13F
JACOBS LEVY EQUITY MANAGEMENT, INC	13F	Company	0.2%	43,600	$410,000	—	31 Dec 2016	13F
TEACHERS ADVISORS, LLC	13F	Company	0.19%	41,436	$389,000	—	31 Dec 2016	13F
D. E. Shaw & Co., Inc.	13F	Company	0.19%	41,270	$387,000	—	31 Dec 2016	13F
TCW GROUP INC	13F	Company	0.18%	40,648	$382,000	—	31 Dec 2016	13F
HIGHBRIDGE CAPITAL MANAGEMENT LLC	13F	Company	0.18%	39,965	$376,000	—	31 Dec 2016	13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F	Company	0.17%	38,492	$362,000	—	31 Dec 2016	13F
Swiss National Bank	13F	Company	0.17%	36,850	$346,000	—	31 Dec 2016	13F
Russell Investments Group, Ltd.	13F	Company	0.17%	36,724	$343,000	—	31 Dec 2016	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	0.16%	34,930	$328,000	—	31 Dec 2016	13F
PRELUDE CAPITAL MANAGEMENT, LLC	13F	Company	0.14%	32,196	$303,000	—	31 Dec 2016	13F
ProShare Advisors LLC	13F	Company	0.14%	31,601	$297,000	—	31 Dec 2016	13F
NEW YORK STATE COMMON RETIREMENT FUND	13F	Company	0.13%	29,430	$277,000	—	31 Dec 2016	13F
Trexquant Investment LP	13F	Company	0.13%	29,007	$273,000	—	31 Dec 2016	13F
VIRTUS ADVISERS, LLC	13F	Company	0.12%	27,446	$258,000	—	31 Dec 2016	13F
METROPOLITAN LIFE INSURANCE CO/NY	13F	Company	0.1%	21,911	$206,000	—	31 Dec 2016	13F
Nationwide Fund Advisors	13F	Company	0.09%	20,496	$193,000	—	31 Dec 2016	13F
WELLS FARGO & COMPANY/MN	13F	Company	0.09%	20,322	$191,000	—	31 Dec 2016	13F

Institutional Holders of Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) as of Q1 2017

As of 31 Mar 2017, Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) was held by 79 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 26,846,913 shares. The largest 10 holders included WELLINGTON MANAGEMENT GROUP LLP, FMR LLC, Palo Alto Investors, LLC, FRANKLIN RESOURCES INC, BlackRock Inc., VANGUARD GROUP INC, Tekla Capital Management LLC, JPMORGAN CHASE & CO, STATE STREET CORP, and TEACHERS ADVISORS, LLC. This page lists 79 institutional shareholders reporting positions in this security for the Q1 2017 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q1 2017 vs Q4 2016 Across Filers

Q4 2016 holders

Q1 2017 holders

Holder diff

-6

Investor	Q4 2016 Shares	Q1 2017 Shares	Share Diff	Share Chg %	Q4 2016 Value $	Q1 2017 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.