Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)

Q: What does CUSIP 48576U106 represent in this 13F holders report?

CUSIP 48576U106 is the security identifier for KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in Q4 2016?

85 institutional investors reported KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share for Q4 2016. Use the holders table for investor-level position and value details.

CUSIP: 48576U106

Q4 2016 13F Holders as of 31 Dec 2016

Type / Class: Equity / Common Stock, par value $0.0001 per share
Shares outstanding: 22,242,217
Total 13F shares: 25,467,293
Share change: +2,262,107
Total reported value: $239,390,343
Put/Call ratio: 0%
Price per share: $9.40
Number of holders: 85
Value change: +$21,237,489
Number of buys: 48
Number of sells: 22

Quarterly Holders Quick Answers

What is CUSIP 48576U106?
CUSIP 48576U106 identifies KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in SEC institutional holdings data.

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Newer quarter: Q1 2017
Previous quarter: Q3 2016

Recent filing periods for CUSIP 48576U106:

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Top shareholders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FMR LLC	13F	Company	24%	5,359,831	$52,151,000	—	30 Sep 2016	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	19%	4,258,985	$41,439,000	—	30 Sep 2016	13F
FRANKLIN RESOURCES INC	13F	Company	15%	3,277,209	$31,887,000	—	30 Sep 2016	13F
Palo Alto Investors LP	13F	Company	14%	3,085,849	$30,025,000	—	30 Sep 2016	13F
BlackRock Fund Advisors	13F	Company	5.2%	1,147,261	$11,163,000	—	30 Sep 2016	13F
VANGUARD GROUP INC	13F	Company	4%	881,605	$8,578,000	—	30 Sep 2016	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	3.9%	871,861	$8,483,000	—	30 Sep 2016	13F
BlackRock Institutional Trust Company, N.A.	13F	Company	2.4%	539,090	$5,245,000	—	30 Sep 2016	13F
Tekla Capital Management LLC	13F	Company	2.2%	500,324	$4,868,000	—	30 Sep 2016	13F
STATE STREET CORP	13F	Company	1.7%	381,088	$3,708,000	—	30 Sep 2016	13F
JPMORGAN CHASE & CO	13F	Company	1.7%	374,000	$3,639,000	—	30 Sep 2016	13F
NORTHERN TRUST CORP	13F	Company	1.2%	272,316	$2,650,000	—	30 Sep 2016	13F
S.c.a. Candriam	13F	Individual	1.2%	270,000	$2,627,000	—	30 Sep 2016	13F
BAKER BROS. ADVISORS LP	13F	Company	0.98%	216,990	$2,111,000	—	30 Sep 2016	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.66%	146,487	$1,425,000	—	30 Sep 2016	13F
BlackRock Investment Management, LLC	13F	Company	0.46%	101,972	$992,000	—	30 Sep 2016	13F
DEUTSCHE BANK AG\	13F	Company	0.44%	97,903	$951,000	—	30 Sep 2016	13F
Bank of New York Mellon Corp	13F	Company	0.39%	87,805	$854,000	—	30 Sep 2016	13F
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	13F	Company	0.39%	87,466	$851,000	—	30 Sep 2016	13F
RHUMBLINE ADVISERS	13F	Company	0.37%	81,580	$794,000	—	30 Sep 2016	13F
TIAA CREF INVESTMENT MANAGEMENT LLC	13F	Company	0.35%	78,027	$759,000	—	30 Sep 2016	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.28%	63,364	$617,000	—	30 Sep 2016	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.26%	58,341	$568,000	—	30 Sep 2016	13F
Piermont Capital Management Inc.	13F	Company	0.23%	52,080	$507,000	—	30 Sep 2016	13F
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	13F	Company	0.22%	49,844	$485,000	—	30 Sep 2016	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.22%	48,514	$472,000	—	30 Sep 2016	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.21%	45,804	$446,000	—	30 Sep 2016	13F
TCW GROUP INC	13F	Company	0.18%	40,648	$396,000	—	30 Sep 2016	13F
JACOBS LEVY EQUITY MANAGEMENT, INC	13F	Company	0.18%	39,900	$388,000	—	30 Sep 2016	13F
Swiss National Bank	13F	Company	0.17%	36,850	$359,000	—	30 Sep 2016	13F
NEW YORK STATE COMMON RETIREMENT FUND	13F	Company	0.16%	36,696	$357,000	—	30 Sep 2016	13F
TEACHERS ADVISORS, LLC	13F	Company	0.16%	36,017	$350,000	—	30 Sep 2016	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	0.16%	34,930	$340,000	—	30 Sep 2016	13F
VIRTUS ADVISERS, LLC	13F	Company	0.14%	30,617	$298,000	—	30 Sep 2016	13F
CITADEL ADVISORS LLC	13F	Company	0.13%	29,353	$286,000	—	30 Sep 2016	13F
D. E. Shaw & Co., Inc.	13F	Company	0.13%	28,219	$275,000	—	30 Sep 2016	13F
Virtu KCG Holdings LLC	13F	Company	0.12%	27,214	$265,000	—	30 Sep 2016	13F
ProShare Advisors LLC	13F	Company	0.11%	25,032	$244,000	—	30 Sep 2016	13F
CREDIT SUISSE AG/	13F	Company	0.11%	24,818	$242,000	—	30 Sep 2016	13F
First Allied Advisory Services, Inc.	13F	Company	0.09%	20,850	$203,000	—	30 Sep 2016	13F
PARAMETRIC PORTFOLIO ASSOCIATES LLC	13F	Company	0.09%	19,925	$194,000	—	30 Sep 2016	13F
METROPOLITAN LIFE INSURANCE CO/NY	13F	Company	0.09%	19,451	$189,000	—	30 Sep 2016	13F
HIGHBRIDGE CAPITAL MANAGEMENT LLC	13F	Company	0.09%	19,280	$188,000	—	30 Sep 2016	13F
MORGAN STANLEY	13F	Company	0.08%	17,877	$175,000	—	30 Sep 2016	13F
MANUFACTURERS LIFE INSURANCE COMPANY, THE	13F	Company	0.08%	16,703	$162,000	—	30 Sep 2016	13F
BANK OF MONTREAL /CAN/	13F	Company	0.07%	16,318	$159,000	—	30 Sep 2016	13F
TUDOR INVESTMENT CORP ET AL	13F	Company	0.07%	16,313	$159,000	—	30 Sep 2016	13F
Endurance Wealth Management, Inc.	13F	Company	0.07%	16,000	$156,000	—	30 Sep 2016	13F
STONERIDGE INVESTMENT PARTNERS LLC	13F	Company	0.07%	15,822	$154,000	—	30 Sep 2016	13F
Nationwide Fund Advisors	13F	Company	0.07%	15,372	$150,000	—	30 Sep 2016	13F

Institutional Holders of Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) as of Q4 2016

As of 31 Dec 2016, Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) was held by 85 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 25,467,293 shares. The largest 10 holders included WELLINGTON MANAGEMENT GROUP LLP, FMR LLC, FRANKLIN RESOURCES INC, Palo Alto Investors, LLC, BlackRock Fund Advisors, VANGUARD GROUP INC, MILLENNIUM MANAGEMENT LLC, BlackRock Institutional Trust Company, N.A., Tekla Capital Management LLC, and JPMORGAN CHASE & CO. This page lists 85 institutional shareholders reporting positions in this security for the Q4 2016 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2016 vs Q3 2016 Across Filers

Q3 2016 holders

Q4 2016 holders

Holder diff

Investor	Q3 2016 Shares	Q4 2016 Shares	Share Diff	Share Chg %	Q3 2016 Value $	Q4 2016 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.