Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share (EWTX)

Q: What does CUSIP 28036F105 represent in this 13F holders report?

CUSIP 28036F105 is the security identifier for EWTX - Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held EWTX - Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share in Q4 2025?

197 institutional investors reported EWTX - Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share for Q4 2025. Use the holders table for investor-level position and value details.

CUSIP: 28036F105

Q4 2025 13F Holders as of 31 Dec 2025

Type / Class: Equity / Common Stock, par value $0.0001 per share
Shares outstanding: 109,183,673
Total 13F shares: 121,822,383
Share change: +10,277,553
Total reported value: $3,022,521,297
Put/Call ratio: 96%
Price per share: $24.82
Number of holders: 197
Value change: +$263,739,340
Number of buys: 106
Number of sells: 74

Quarterly Holders Quick Answers

What is CUSIP 28036F105?
CUSIP 28036F105 identifies EWTX - Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share in SEC institutional holdings data.

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Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q1 2026
Previous quarter: Q3 2025

Recent filing periods for CUSIP 28036F105:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of EWTX - Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
ORBIMED ADVISORS LLC	13F 13D/G 3/4/5	Company · Director, 10%+ Owner	14% from 13D/G	15,518,492	$251,709,940	—	30 Sep 2025	13F 13D/G 3/4/5
RA CAPITAL MANAGEMENT, L.P.	13D/G 13F	Company	9.9%	10,428,437	$169,149,248	$0	30 Sep 2025	13D/G 13F
Paradigm Biocapital Advisors LP	13D/G 13F	Company	6.2%	6,541,210	$161,371,651	+$44,462,272	31 Dec 2025	13D/G 13F
BAKER BROS. ADVISORS LP	13F 13D/G	Company	6.9% from 13D/G	7,305,940	$118,502,347	—	30 Sep 2025	13F 13D/G
BlackRock, Inc.	13F 13D/G	Company	5.5% from 13D/G	6,351,487	$103,021,118	—	30 Sep 2025	13F 13D/G
Novo Holdings A/S	3/4/5 13F	10%+ Owner · Company	4.9% from 13F	6,071,703	$95,781,722	—	14 Sep 2022	3/4/5 13F
BRAIDWELL LP	13F	Company	4.8%	5,210,831	$84,519,679	—	30 Sep 2025	13F
JANUS HENDERSON GROUP PLC	13F 13D/G	Company	4.7% from 13D/G	4,979,331	$80,804,202	—	30 Sep 2025	13F 13D/G
VANGUARD GROUP INC	13F	Company	4.4%	4,803,941	$77,919,924	—	30 Sep 2025	13F
Cormorant Asset Management, LP	13F	Company	3.7%	4,010,000	$65,042,200	—	30 Sep 2025	13F
Siren, L.L.C.	13F	Individual	3.6%	3,897,099	$63,210,946	—	30 Sep 2025	13F
PERCEPTIVE ADVISORS LLC	13F 13D/G	Company	4.4% from 13D/G	3,795,894	$61,569,401	—	30 Sep 2025	13F 13D/G
Bellevue Group AG	13F	Company	2.5%	2,775,997	$45,026,671	—	30 Sep 2025	13F
DRIEHAUS CAPITAL MANAGEMENT LLC	13F	Company	2%	2,228,285	$36,142,783	—	30 Sep 2025	13F
MPM BioImpact LLC	13F	Company	1.6%	1,720,741	$27,910,419	—	30 Sep 2025	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	1.6%	1,717,641	$27,864,280	—	30 Sep 2025	13F
STATE STREET CORP	13F	Company	1.6%	1,699,909	$27,572,524	—	30 Sep 2025	13F
Integral Health Asset Management, LLC	13F	Company	1.4%	1,500,000	$24,330,000	—	30 Sep 2025	13F
First Light Asset Management, LLC	13F	Company	1.3%	1,414,994	$22,951,203	—	30 Sep 2025	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	1.1%	1,183,136	$19,187,177	—	30 Sep 2025	13F
AMERICAN CENTURY COMPANIES INC	13F	Company	1%	1,095,473	$17,768,606	—	30 Sep 2025	13F
New Leaf Venture Partners, L.L.C.	13F	Company	0.94%	1,030,161	$16,709,211	—	30 Sep 2025	13F
MORGAN STANLEY	13F	Company	0.8%	869,678	$14,106,178	—	30 Sep 2025	13F
DEERFIELD MANAGEMENT COMPANY, L.P.	13F	Company	0.7%	765,694	$12,419,557	—	30 Sep 2025	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	0.66%	725,425	$11,766,394	—	30 Sep 2025	13F
Artisan Partners Limited Partnership	13F	Company	0.66%	718,175	$11,648,799	—	30 Sep 2025	13F
D. E. Shaw & Co., Inc.	13F	Company	0.62%	677,561	$10,990,039	—	30 Sep 2025	13F
Aberdeen Group plc	13F	Company	0.57%	619,878	$10,054,421	—	30 Sep 2025	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.55%	597,603	$9,693,121	—	30 Sep 2025	13F
NORTHERN TRUST CORP	13F	Company	0.54%	587,882	$9,535,446	—	30 Sep 2025	13F
EVENTIDE ASSET MANAGEMENT, LLC	13F	Company	0.52%	568,310	$9,217,988	—	30 Sep 2025	13F
Qube Research & Technologies Ltd	13F	Company	0.51%	555,713	$9,013,665	—	30 Sep 2025	13F
Peter A. Thompson	3/4/5	Director, 10%+ Owner	— mixed-class rows	473,792 mixed-class rows	$8,933,533	—	16 Jun 2025	3/4/5
Parkman Healthcare Partners LLC	13F	Company	0.5%	550,173	$8,923,806	—	30 Sep 2025	13F
CITIGROUP INC	13F	Company	0.49%	538,453	$8,733,707	—	30 Sep 2025	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.48%	527,827	$8,561,354	—	30 Sep 2025	13F
Sofinnova Investments, Inc.	13F	Company	0.48%	520,240	$8,438,293	—	30 Sep 2025	13F
Eversept Partners, LP	13F	Company	0.46%	502,234	$8,146,235	—	30 Sep 2025	13F
Opaleye Management Inc.	13F	Company	0.46%	500,000	$8,110,000	—	30 Sep 2025	13F
VICTORY CAPITAL MANAGEMENT INC	13F	Company	0.46%	498,646	$8,088,038	—	30 Sep 2025	13F
TANG CAPITAL MANAGEMENT LLC	13F	Company	0.4%	431,300	$6,995,686	—	30 Sep 2025	13F
Kevin Koch	3/4/5	President and CEO, Director	— mixed-class rows	981,899 mixed-class rows	$6,183,518	-$177,122	12 Aug 2025	3/4/5
Granahan Investment Management, LLC	13F	Company	0.31%	339,617	$5,508,588	—	30 Sep 2025	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.29%	321,132	$5,208,761	—	30 Sep 2025	13F
Sio Capital Management, LLC	13F	Company	0.28%	307,181	$4,982,476	—	30 Sep 2025	13F
Kynam Capital Management, LP	13F	Company	0.23%	253,979	$4,119,539	—	30 Sep 2025	13F
FMR LLC	13F	Company	0.23%	253,325	$4,108,931	—	30 Sep 2025	13F
KENNEDY CAPITAL MANAGEMENT LLC	13F	Company	0.23%	250,622	$4,065,089	—	30 Sep 2025	13F
BARCLAYS PLC	13F	Company	0.21%	234,650	$3,806,022	—	30 Sep 2025	13F
Woodline Partners LP	13F	Company	0.21%	224,190	$3,636,362	—	30 Sep 2025	13F

Institutional Holders of Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share (EWTX) as of Q4 2025

As of 31 Dec 2025, Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share (EWTX) was held by 197 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 121,822,383 shares. The largest 10 holders included ORBIMED ADVISORS LLC, RA CAPITAL MANAGEMENT, L.P., BlackRock, Inc., BAKER BROS. ADVISORS LP, Paradigm Biocapital Advisors LP, NOVO HOLDINGS A/S, BRAIDWELL LP, VANGUARD GROUP INC, JANUS HENDERSON GROUP PLC, and Siren, L.L.C.. This page lists 197 institutional shareholders reporting positions in this security for the Q4 2025 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders

172

Q4 2025 holders

197

Holder diff

Investor	Q3 2025 Shares	Q4 2025 Shares	Share Diff	Share Chg %	Q3 2025 Value $	Q4 2025 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.