Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share (EWTX)

CUSIP: 28036F105

Q3 2025 13F Holders as of 30 Sep 2025

Type / Class
Equity / Common Stock, par value $0.0001 per share
Shares outstanding
109,183,673
Total 13F shares
111,964,035
Share change
-6,779,965
Total reported value
$1,816,272,411
Put/Call ratio
53%
Price per share
$16.22
Number of holders
172
Value change
-$102,066,033
Number of buys
75
Number of sells
85

Quarterly Holders Quick Answers

What is CUSIP 28036F105?
CUSIP 28036F105 identifies EWTX - Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share in SEC institutional holdings data.

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Top shareholders of EWTX - Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
ORBIMED ADVISORS LLC
13D/G 3/4/5 13F
Director, 10%+ Owner · Company
14%
15,252,867
$234,894,152 $0 09 May 2025
RA CAPITAL MANAGEMENT, L.P.
13D/G 13F
Company
9.9%
10,428,437
$169,149,248 $0 30 Sep 2025
Novo Holdings A/S
3/4/5 13F
10%+ Owner · Company
4.9%
from 13F
6,071,703
$95,781,722 14 Sep 2022
BAKER BROS. ADVISORS LP
13F 13D/G
Company
6.9%
from 13D/G
7,305,940
$95,780,873 30 Jun 2025
BlackRock, Inc.
13F 13D/G
Company
5.5%
from 13D/G
6,781,046
$88,899,513 30 Jun 2025
JANUS HENDERSON GROUP PLC
13D/G 13F
Company
4.7%
4,979,331
$80,764,749 -$8,499,572 30 Sep 2025
Paradigm Biocapital Advisors LP
13F
Company
5.6%
6,142,344
$80,526,130 30 Jun 2025
13F
BRAIDWELL LP
13F
Company
4.8%
5,210,831
$68,313,994 30 Jun 2025
13F
VANGUARD GROUP INC
13F
Company
4.4%
4,841,500
$63,472,065 30 Jun 2025
13F
PERCEPTIVE ADVISORS LLC
13F 13D/G
Company
4.4%
from 13D/G
4,639,949
$60,829,731 30 Jun 2025
Cormorant Asset Management, LP
13F
Company
3.9%
4,251,992
$55,743,615 30 Jun 2025
13F
Siren, L.L.C.
13F
Individual
2.9%
3,160,298
$41,431,507 30 Jun 2025
13F
Bellevue Group AG
13F
Company
2.5%
2,775,997
$36,393,321 30 Jun 2025
13F
DRIEHAUS CAPITAL MANAGEMENT LLC
13F
Company
1.9%
2,101,781
$27,554,349 30 Jun 2025
13F
DEERFIELD MANAGEMENT COMPANY, L.P.
13F
Company
1.9%
2,067,320
$27,102,565 30 Jun 2025
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
1.6%
1,797,215
$23,564,445 30 Jun 2025
13F
STATE STREET CORP
13F
Company
1.6%
1,781,501
$23,355,478 30 Jun 2025
13F
MPM BioImpact LLC
13F
Company
1.6%
1,720,741
$22,558,915 30 Jun 2025
13F
First Light Asset Management, LLC
13F
Company
1.6%
1,714,019
$22,470,789 30 Jun 2025
13F
Artisan Partners Limited Partnership
13F
Company
1.3%
1,379,068
$18,079,581 30 Jun 2025
13F
Woodline Partners LP
13F
Company
1%
1,096,863
$14,379,874 30 Jun 2025
13F
DIMENSIONAL FUND ADVISORS LP
13F
Company
0.96%
1,048,936
$13,751,970 30 Jun 2025
13F
New Leaf Venture Partners, L.L.C.
13F
Company
0.94%
1,030,161
$13,505,411 30 Jun 2025
13F
Integral Health Asset Management, LLC
13F
Company
0.92%
1,000,000
$13,110,000 30 Jun 2025
13F
Polar Capital Holdings Plc
13F
Company
0.89%
975,000
$12,782,250 30 Jun 2025
13F
MILLENNIUM MANAGEMENT LLC
13F
Company
0.84%
921,965
$12,086,961 30 Jun 2025
13F
AMERICAN CENTURY COMPANIES INC
13F
Company
0.72%
783,166
$10,267,325 30 Jun 2025
13F
MORGAN STANLEY
13F
Company
0.67%
727,714
$9,540,337 30 Jun 2025
13F
CITIGROUP INC
13F
Company
0.66%
724,899
$9,503,426 30 Jun 2025
13F
Sofinnova Investments, Inc.
13F
Company
0.66%
716,873
$9,398,205 30 Jun 2025
13F
Peter A. Thompson
3/4/5
Director, 10%+ Owner
mixed-class rows
473,792
mixed-class rows
$8,933,533 16 Jun 2025
Parkman Healthcare Partners LLC
13F
Company
0.59%
647,331
$8,486,509 30 Jun 2025
13F
GOLDMAN SACHS GROUP INC
13F
Company
0.58%
631,743
$8,282,150 30 Jun 2025
13F
NORTHERN TRUST CORP
13F
Company
0.55%
602,898
$7,903,993 30 Jun 2025
13F
D. E. Shaw & Co., Inc.
13F
Company
0.55%
595,432
$7,806,114 30 Jun 2025
13F
Foresite Capital Management VI LLC
13F
Company
0.54%
585,000
$7,669,350 30 Jun 2025
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.53%
579,104
$7,592,053 30 Jun 2025
13F
EVENTIDE ASSET MANAGEMENT, LLC
13F
Company
0.52%
568,310
$7,450,544 30 Jun 2025
13F
Sio Capital Management, LLC
13F
Company
0.49%
539,730
$7,075,860 30 Jun 2025
13F
Qube Research & Technologies Ltd
13F
Company
0.46%
499,917
$6,553,912 30 Jun 2025
13F
Opaleye Management Inc.
13F
Company
0.45%
490,000
$6,423,900 30 Jun 2025
13F
Kevin Koch
3/4/5
President and CEO, Director
mixed-class rows
981,899
mixed-class rows
$6,183,518 -$177,122 12 Aug 2025
FMR LLC
13F
Company
0.43%
470,717
$6,171,106 30 Jun 2025
13F
Aberdeen Group plc
13F
Company
0.41%
443,319
$5,811,912 30 Jun 2025
13F
VICTORY CAPITAL MANAGEMENT INC
13F
Company
0.41%
442,837
$5,805,593 30 Jun 2025
13F
TANG CAPITAL MANAGEMENT LLC
13F
Company
0.4%
431,300
$5,654,343 30 Jun 2025
13F
Granahan Investment Management, LLC
13F
Company
0.37%
405,478
$5,315,817 30 Jun 2025
13F
Eversept Partners, LP
13F
Company
0.36%
392,739
$5,148,808 30 Jun 2025
13F
CITADEL ADVISORS LLC
13F
Company
0.3%
325,249
$4,264,014 30 Jun 2025
13F
Nuveen, LLC
13F
Company
0.29%
317,173
$4,158,138 30 Jun 2025
13F

Institutional Holders of Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share (EWTX) as of Q3 2025

As of 30 Sep 2025, Edgewise Therapeutics, Inc. - Common Stock, par value $0.0001 per share (EWTX) was held by 172 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 111,964,035 shares. The largest 10 holders included ORBIMED ADVISORS LLC, RA CAPITAL MANAGEMENT, L.P., BAKER BROS. ADVISORS LP, BlackRock, Inc., Paradigm Biocapital Advisors LP, NOVO HOLDINGS A/S, BRAIDWELL LP, JANUS HENDERSON GROUP PLC, VANGUARD GROUP INC, and Cormorant Asset Management, LP. This page lists 172 institutional shareholders reporting positions in this security for the Q3 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q3 2025 vs Q2 2025 Across Filers

Q2 2025 holders
177
Q3 2025 holders
172
Holder diff
-5
Investor Q2 2025 Shares Q3 2025 Shares Share Diff Share Chg % Q2 2025 Value $ Q3 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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