Security Snapshot

BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (BCYC) Institutional Ownership

CUSIP: 088786108

13F Institutional Holders and Ownership History from Q2 2019 to Q2 2026

Latest Period

Q2 2026

Institutions Reporting

104

Shares (Excl. Options)

37,256,063

Price

$4.24

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Latest holder snapshot 5 signals
Portfolio coverage rank
0%
Share change
-203,768
Value change
-$2,311,131
Number of holders
104
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
50,565,476
SEC-reported price per share
$4.21
Insider filing price
$4.21
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share is tracked under CUSIP 088786108.
  • 104 institutions reported positions in Q2 2026.
  • 6 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 98 to 104 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from $173,587,357 to $157,883,182.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 104 institutions filings for Q2 2026.

Open SEC evidence

Security key

088786108

Latest holder period

Q2 2026

13F holders

104

13D/G owners

6

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
6
Security
BCYC
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Forbion Growth Opportunities Fund II Cooperatief U.A. 7.3% $28,343,629 3,452,330 Forbion Growth Opportunities Fund II Cooperatief U.A. 21 Nov 2024
ARMISTICE CAPITAL, LLC 6.7% -0.43% $14,543,440 3,398,000 0% Armistice Capital, LLC 30 Jun 2026
Long Focus Capital Management, LLC 6.6% $16,487,221 3,310,687 LONG FOCUS CAPITAL MANAGEMENT, LLC 31 Mar 2026
Point72 Asset Management, L.P. 3.9% -49% $14,882,536 -$15,032,008 1,860,317 -50% Point72 Asset Management, L.P. 30 Jun 2025
Invus Global Management, LLC 3.1% -53% $7,773,192 -$7,909,072 1,560,882 -50% Raymond Debbane 31 Mar 2026
Deep Track Capital, LP 2.4% -54% $9,625,952 -$12,943,416 1,203,244 -57% Deep Track Capital, LP 30 Jun 2025

As of 30 Jun 2026, 104 institutional investors reported holding 37,256,063 shares of BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (BCYC). This represents 74% of the company’s total 50,565,476 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
68%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BAKER BROS. ADVISORS LP 22% 10,885,357 0% 0.23% $46,153,914
FCPM III SERVICES B.V. 6.9% 3,468,430 0% 2% $14,706,143
ARMISTICE CAPITAL, LLC 6.7% 3,398,000 0% 0.4% $14,407,520
Long Focus Capital Management, LLC 6.5% 3,310,687 0% 0.58% $14,037,313
ACADIAN ASSET MANAGEMENT LLC 3.9% 1,968,025 0% 0.01% $8,319,000
RENAISSANCE TECHNOLOGIES LLC 3% 1,533,400 +57% 0.01% $6,501,616
GSK plc 3% 1,529,561 0% 1.1% $6,485,339
PRICE T ROWE ASSOCIATES INC /MD/ 1.8% 902,150 -12% 0% $3,826,000
MARSHALL WACE, LLP 1.6% 797,940 +111% 0% $3,383,266
Qube Research & Technologies Ltd 1.5% 775,567 +151% 0% $3,288,404
MORGAN STANLEY 1.3% 667,269 +7.9% 0% $2,829,221
SCHRODER INVESTMENT MANAGEMENT GROUP 1.2% 615,833 0% 0% $2,555,707
CITADEL ADVISORS LLC 1.1% 554,225 +47% 0% $2,349,914
MILLENNIUM MANAGEMENT LLC 1.1% 553,967 +95% 0% $2,348,820
Peapod Lane Capital LLC 1.1% 537,978 +344% 1.5% $2,281,027
DIADEMA PARTNERS LP 0.92% 462,724 -2.9% 0.74% $1,961,950
TWO SIGMA INVESTMENTS, LP 0.86% 434,577 +164% 0% $1,842,606
JANE STREET GROUP, LLC 0.78% 392,163 +80% 0% $1,662,771
Birchview Capital, LP 0.62% 313,616 -32% 0.62% $1,329,732
BlackRock, Inc. 0.55% 280,386 +0.5% 0% $1,188,837
MOORE CAPITAL MANAGEMENT, LP 0.54% 275,000 0% 0.03% $1,166,000
Rangeley Capital, LLC 0.5% 253,500 +9.1% 1.1% $1,074,840
Palo Alto Investors LP 0.4% 201,890 0% 0.12% $856,014
Sculptor Capital LP 0.39% 197,904 0.01% $839,113
Eversept Partners, LP 0.38% 190,715 0% 0.04% $808,632

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
29
Latest
Q2 2026
Rows shown
1-25 of 29
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 37,256,063 $157,883,182 -$2,311,131 $4.24 104
2026 Q1 37,459,831 $173,587,357 -$22,803,169 $4.64 98
2025 Q4 39,173,346 $277,662,853 +$3,442,632 $7.08 109
2025 Q3 36,906,185 $285,619,779 -$29,768,237 $7.74 99
2025 Q2 41,200,406 $286,338,478 -$7,404,258 $6.95 110
2025 Q1 41,735,285 $354,350,748 -$8,366,393 $8.49 95
2024 Q4 41,890,221 $586,472,317 -$21,543,705 $14.00 96
2024 Q3 40,439,351 $915,266,321 +$21,080,974 $22.63 104
2024 Q2 39,722,044 $803,959,492 +$167,237,644 $20.24 105
2024 Q1 30,475,266 $758,677,656 +$6,974,793 $24.90 93
2023 Q4 31,374,408 $567,252,558 -$28,664,876 $18.08 98
2023 Q3 32,418,922 $651,281,538 +$165,201,151 $20.09 101
2023 Q2 24,236,173 $618,449,426 +$18,484,148 $25.52 84
2023 Q1 23,558,818 $498,895,905 -$47,151,037 $21.27 89
2022 Q4 23,577,228 $697,847,861 +$39,624,167 $29.60 87
2022 Q3 23,196,999 $539,598,338 +$13,911,506 $23.26 77
2022 Q2 22,709,672 $381,075,755 -$69,885,312 $16.78 78
2022 Q1 20,168,148 $884,247,452 -$137,175,184 $43.88 100
2021 Q4 21,550,279 $1,311,636,981 +$387,558,387 $60.87 98
2021 Q3 14,210,499 $591,072,741 +$80,484,868 $41.59 67
2021 Q2 12,412,613 $376,901,461 +$30,169,498 $30.36 53
2021 Q1 11,420,830 $341,203,000 +$123,064,104 $29.87 39
2020 Q4 7,328,435 $131,544,000 -$3,975,466 $17.95 27
2020 Q3 7,550,163 $143,830,000 +$24,085,212 $19.05 18
2020 Q2 6,287,737 $98,861,000 +$4,298,929 $15.74 15
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