BICYCLE THERAPEUTICS PLC - Common Stock (BCYC) Institutional Ownership

CUSIP: 088786108

13F Institutional Holders and Ownership History from Q2 2019 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
BCYC on Nasdaq
Shares outstanding
49,984,905
Price per share
$5.63
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
39,173,179
Total reported value
$277,661,671
% of total 13F portfolios
0%
Share change
+532,216
Value change
+$3,442,632
Number of holders
108
Price from insider filings
$5.63
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Investment Quick Answers

What is CUSIP 088786108?
CUSIP 088786108 identifies BCYC - BICYCLE THERAPEUTICS PLC - Common Stock in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of BICYCLE THERAPEUTICS PLC - Common Stock (BCYC) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Forbion Growth Opportunities Fund II Cooperatief U.A. 7.3% $28,343,629 3,452,330 Forbion Growth Opportunities Fund II Cooperatief U.A. 21 Nov 2024
ARMISTICE CAPITAL, LLC 6.5% +15% $21,292,880 +$3,711,120 3,236,000 +21% Armistice Capital, LLC 31 Dec 2025
Invus Global Management, LLC 6.3% $17,729,146 3,149,049 Raymond Debbane 25 Feb 2026
Point72 Asset Management, L.P. 3.9% -49% $14,882,536 -$15,032,008 1,860,317 -50% Point72 Asset Management, L.P. 30 Jun 2025
Deep Track Capital, LP 2.4% -54% $9,625,952 -$12,943,416 1,203,244 -57% Deep Track Capital, LP 30 Jun 2025

As of 31 Dec 2025, 108 institutional investors reported holding 39,173,179 shares of BICYCLE THERAPEUTICS PLC - Common Stock (BCYC). This represents 78% of the company’s total 49,984,905 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of BICYCLE THERAPEUTICS PLC - Common Stock (BCYC) together control 72% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BAKER BROS. ADVISORS LP 22% 10,885,357 0% 0.45% $77,068,328
FCPM III SERVICES B.V. 6.9% 3,468,430 +0.47% 3.2% $24,556,484
ARMISTICE CAPITAL, LLC 6.5% 3,236,000 +8.7% 0.56% $22,910,880
WESTFIELD CAPITAL MANAGEMENT CO LP 6% 3,016,026 +2.2% 0.09% $21,353,464
Siren, L.L.C. 4% 2,012,752 0% 0.43% $14,250,284
ACADIAN ASSET MANAGEMENT LLC 3.3% 1,671,258 +27% 0.02% $11,806,000
Long Focus Capital Management, LLC 3.3% 1,633,091 +15% 0.59% $11,562,284
GSK plc 3.1% 1,529,561 0% 1.4% $10,829,292
Candriam S.C.A. 2.4% 1,192,279 +1.7% 0.04% $8,441,695
PRICE T ROWE ASSOCIATES INC /MD/ 2.3% 1,171,787 -15% 0% $8,297,000
PRINCIPAL FINANCIAL GROUP INC 2.3% 1,148,272 -0.01% 0% $8,129,766
SCHRODER INVESTMENT MANAGEMENT GROUP 1.2% 584,770 0% $3,976,436
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 1.1% 568,225 0% $4,023,000
RENAISSANCE TECHNOLOGIES LLC 1.1% 566,600 +9.2% 0.01% $4,011,528
SILVERCREST ASSET MANAGEMENT GROUP LLC 0.95% 476,976 0% 0.02% $3,376,990
MORGAN STANLEY 0.93% 465,222 -43% 0% $3,293,773
Birchview Capital, LP 0.93% 462,700 +200% 1.9% $3,275,916
BlackRock, Inc. 0.67% 332,889 +18% 0% $2,356,854
MILLENNIUM MANAGEMENT LLC 0.65% 326,626 -69% 0% $2,312,512
Jefferies Financial Group Inc. 0.59% 297,247 -26% 0.02% $2,104,509
MOORE CAPITAL MANAGEMENT, LP 0.55% 275,000 +120% 0.04% $1,947,000
CITADEL ADVISORS LLC 0.54% 271,383 +44% 0% $1,921,391
Palo Alto Investors LP 0.44% 221,071 0% 0.22% $1,565,183
PINNACLE ASSOCIATES LTD 0.38% 190,480 -3.1% 0.02% $1,348,598
PLATINUM INVESTMENT MANAGEMENT LTD 0.37% 184,603 0% 0.3% $1,306,989

Institutional Holders of BICYCLE THERAPEUTICS PLC - Common Stock (BCYC) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 39,173,179 $277,661,671 +$3,442,632 $7.08 108
2025 Q3 36,906,185 $285,619,779 -$29,768,237 $7.74 99
2025 Q2 41,200,406 $286,338,478 -$7,404,258 $6.95 110
2025 Q1 41,735,285 $354,350,748 -$8,366,393 $8.49 95
2024 Q4 41,890,221 $586,472,317 -$21,543,705 $14.00 96
2024 Q3 40,439,351 $915,266,321 +$21,080,974 $22.63 104
2024 Q2 39,722,044 $803,959,492 +$167,237,644 $20.24 105
2024 Q1 30,475,266 $758,677,656 +$6,974,793 $24.90 93
2023 Q4 31,374,408 $567,252,558 -$28,664,876 $18.08 98
2023 Q3 32,418,922 $651,281,538 +$165,201,151 $20.09 101
2023 Q2 24,236,173 $618,449,426 +$18,484,148 $25.52 84
2023 Q1 23,558,818 $498,895,905 -$47,151,037 $21.27 89
2022 Q4 23,577,228 $697,847,861 +$39,624,167 $29.60 87
2022 Q3 23,196,999 $539,598,338 +$13,911,506 $23.26 77
2022 Q2 22,709,672 $381,075,755 -$69,885,312 $16.78 78
2022 Q1 20,168,148 $884,247,452 -$137,175,184 $43.88 100
2021 Q4 21,550,279 $1,311,636,981 +$387,558,387 $60.87 98
2021 Q3 14,210,499 $591,072,741 +$80,484,868 $41.59 67
2021 Q2 12,412,613 $376,901,461 +$30,169,498 $30.36 53
2021 Q1 11,420,830 $341,203,000 +$123,064,104 $29.87 39
2020 Q4 7,328,435 $131,544,000 -$3,975,466 $17.95 27
2020 Q3 7,550,163 $143,830,000 +$24,085,212 $19.05 18
2020 Q2 6,287,737 $98,861,000 +$4,298,929 $15.74 15
2020 Q1 5,977,254 $81,901,000 +$1,078,206 $13.65 12
2019 Q4 5,901,993 $55,657,000 -$6,870,216 $9.43 8
2019 Q3 6,446,149 $73,420,000 -$1,907,302 $11.39 11
2019 Q2 6,635,216 $66,751,000 +$66,751,000 $10.06 14