BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (BCYC)

Q: What does CUSIP 088786108 represent in this 13F holders report?

CUSIP 088786108 is the security identifier for BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share used to aggregate holder disclosures.

Q: How many institutions held BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share in Q2 2022?

78 institutional investors reported BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share for Q2 2022. Use the holders table for investor-level position and value details.

CUSIP: 088786108

Q2 2022 13F Holders as of 30 Jun 2022

Type / Class: Equity / American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share
Shares outstanding: 50,340,741
Total 13F shares: 22,709,672
Share change: +2,541,241
Total reported value: $381,075,755
Put/Call ratio: 10%
Price per share: $16.78
Number of holders: 78
Value change: -$69,885,312
Number of buys: 46
Number of sells: 52

Security key

088786108

Report period

Q2 2022

Institutions

Top holders

BCYC full security history Newer quarter: Q3 2022 Previous quarter: Q1 2022 BICYCLE THERAPEUTICS PLC SEC filings BICYCLE THERAPEUTICS PLC company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 088786108

Newer quarter: Q3 2022 Previous quarter: Q1 2022

Recent filing periods:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
Deep Track Capital, LP	13F	Company	3.7%	1,855,993	$81,441,000	—	31 Mar 2022	13F
JANUS HENDERSON GROUP PLC	13F	Company	3.4%	1,692,774	$74,297,000	—	31 Mar 2022	13F
Point72 Asset Management, L.P.	13F	Company	3.2%	1,619,802	$71,077,000	—	31 Mar 2022	13F
RTW INVESTMENTS, LP	13F	Company	2.5%	1,276,276	$56,003,000	—	31 Mar 2022	13F
EVENTIDE ASSET MANAGEMENT, LLC	13F	Company	2.5%	1,263,471	$55,441,000	—	31 Mar 2022	13F
TYBOURNE CAPITAL MANAGEMENT (HK) LTD	13F	Company	2.3%	1,154,126	$50,643,000	—	31 Mar 2022	13F
Logos Global Management LP	13F	Company	1.9%	950,000	$41,686,000	—	31 Mar 2022	13F
SV Health Investors, LLC	13F	Company	1.8%	917,218	$40,248,000	—	31 Mar 2022	13F
First Light Asset Management, LLC	13F	Company	1.8%	890,174	$39,061,000	—	31 Mar 2022	13F
FMR LLC	13F	Company	1.6%	803,748	$35,268,000	—	31 Mar 2022	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	1.4%	685,876	$30,096,000	—	31 Mar 2022	13F
LOOMIS SAYLES & CO L P	13F	Company	1.3%	643,775	$28,249,000	—	31 Mar 2022	13F
Frazier Life Sciences Management, L.P.	13F	Company	1.2%	603,521	$26,483,000	—	31 Mar 2022	13F
VICTORY CAPITAL MANAGEMENT INC	13F	Company	1.1%	551,415	$23,515,000	—	31 Mar 2022	13F
GREAT POINT PARTNERS LLC	13F	Company	1.1%	550,592	$24,160,000	—	31 Mar 2022	13F
EcoR1 Capital, LLC	13F	Company	1.1%	547,453	$24,022,000	—	31 Mar 2022	13F
Ikarian Capital, LLC	13F	Company	0.95%	478,784	$21,009,000	—	31 Mar 2022	13F
SAMLYN CAPITAL, LLC	13F	Company	0.85%	426,543	$18,717,000	—	31 Mar 2022	13F
DRIEHAUS CAPITAL MANAGEMENT LLC	13F	Company	0.46%	229,290	$10,061,000	—	31 Mar 2022	13F
BlackRock Finance, Inc.	13F	Company	0.38%	190,129	$8,343,000	—	31 Mar 2022	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	0.35%	177,322	$7,781,000	—	31 Mar 2022	13F
Opaleye Management Inc.	13F	Company	0.35%	175,000	$7,679,000	—	31 Mar 2022	13F
Sofinnova Investments, Inc.	13F	Company	0.32%	163,559	$7,177,000	—	31 Mar 2022	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	0.32%	163,367	$7,169,000	—	31 Mar 2022	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.32%	163,265	$7,164,000	—	31 Mar 2022	13F
AXA S.A.	13F	Company	0.29%	145,254	$6,373,746	—	31 Mar 2022	13F
Verition Fund Management LLC	13F	Company	0.27%	134,204	$5,889,000	—	31 Mar 2022	13F
Handelsbanken Fonder AB	13F	Company	0.26%	130,000	$5,704,000	—	31 Mar 2022	13F
TWO SIGMA ADVISERS, LP	13F	Company	0.26%	128,800	$5,652,000	—	31 Mar 2022	13F
Dorsey Wright & Associates	13F	Company	0.25%	126,982	$5,572,000	—	31 Mar 2022	13F
Altium Capital Management LLC	13F	Company	0.24%	120,000	$5,266,000	—	31 Mar 2022	13F
Ghost Tree Capital, LLC	13F	Company	0.2%	100,000	$4,388,000	—	31 Mar 2022	13F
MORGAN STANLEY	13F	Company	0.17%	87,917	$3,857,000	—	31 Mar 2022	13F
RENAISSANCE TECHNOLOGIES LLC	13F	Company	0.13%	64,399	$2,826,000	—	31 Mar 2022	13F
Parkman Healthcare Partners LLC	13F	Company	0.11%	57,295	$2,514,000	—	31 Mar 2022	13F
DAFNA Capital Management LLC	13F	Company	0.11%	53,200	$2,334,000	—	31 Mar 2022	13F
Sio Capital Management, LLC	13F	Company	0.1%	52,788	$2,316,000	—	31 Mar 2022	13F
BOOTHBAY FUND MANAGEMENT, LLC	13F	Company	0.09%	46,770	$2,052,000	—	31 Mar 2022	13F
LMR Partners LLP	13F	Company	0.08%	40,283	$1,768,000	—	31 Mar 2022	13F
FRED ALGER MANAGEMENT, LLC	13F	Company	0.08%	39,246	$1,722,000	—	31 Mar 2022	13F
Caption Management, LLC	13F	Company	0.08%	38,013	$1,667,000	—	31 Mar 2022	13F
Bellevue Group AG	13F	Company	0.07%	36,500	$1,602,000	—	31 Mar 2022	13F
ENVESTNET ASSET MANAGEMENT INC	13F	Company	0.07%	36,164	$1,587,000	—	31 Mar 2022	13F
ACADIAN ASSET MANAGEMENT LLC	13F	Company	0.07%	35,959	$1,576,000	—	31 Mar 2022	13F
STIFEL FINANCIAL CORP	13F	Company	0.06%	31,746	$1,393,000	—	31 Mar 2022	13F
SG Americas Securities, LLC	13F	Company	0.06%	30,379	$1,333,000	—	31 Mar 2022	13F
TD ASSET MANAGEMENT INC	13F	Company	0.06%	29,086	$1,276,000	—	31 Mar 2022	13F
HARBOR CAPITAL ADVISORS, INC.	13F	Company	0.06%	28,942	$1,270,000	—	31 Mar 2022	13F
Jump Financial, LLC	13F	Company	0.06%	28,176	$1,236,000	—	31 Mar 2022	13F
Vident Investment Advisory, LLC	13F	Company	0.04%	21,572	$947,000	—	31 Mar 2022	13F

Institutional Holders of BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (BCYC) as of Q2 2022

As of 30 Jun 2022, BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (BCYC) was held by 78 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 22,709,672 shares. The largest 10 holders included Deep Track Capital, LP, Logos Global Management LP, Point72 Asset Management, L.P., JANUS HENDERSON GROUP PLC, RTW INVESTMENTS, LP, TYBOURNE CAPITAL MANAGEMENT (HK) LTD, Paradigm Biocapital Advisors LP, SAMLYN CAPITAL, LLC, SV Health Investors, LLC, and EVENTIDE ASSET MANAGEMENT, LLC. This page lists 78 institutional shareholders reporting positions in this security for the Q2 2022 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q2 2022 vs Q1 2022 Across Filers

Q1 2022 holders

100

Q2 2022 holders

Holder diff

-22

Investor	Q1 2022 Shares	Q2 2022 Shares	Share Diff	Share Chg %	Q1 2022 Value $	Q2 2022 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.