SEC ownership of BICYCLE THERAPEUTICS PLC

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001761612.

Comparable stake leader

Forbion Growth Opportunities Fund II Cooperatief U.A.

Disclosed value leader

BAKER BROS. ADVISORS LP

Comparable rows

50/50

Latest evidence

30 Jun 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
50 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
Forbion Growth Opportunities Fund II Cooperatief U.A.
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
30 Jun 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001761612
Issuer location
Cambridge, United Kingdom

Ownership snapshot

Top shareholders of BICYCLE THERAPEUTICS PLC (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Forbion Growth Opportunit...
Disclosed value leader
BAKER BROS. ADVISORS LP
Comparable rows
50/50
Latest evidence
30 Jun 2026
13D/G 13F 3/4/5 Lead comparable stake: 7.3% 13D/G row: Forbion Growth Opportunities Fund II Cooperatief U.A. Showing 1-8 of 50 holder rows.

Quick read

Forbion Growth Opportunities Fund II Cooperatief U.A. leads the comparable SEC ownership view at 7.3%.

50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Forbion Growth Opportunities Fund II Cooperatief U.A.'s linked filing trail.
Comparable ownership Top 5
Forbion Growth Opportunities Fund... 7.3%
ARMISTICE CAPITAL, LLC 6.7%
Long Focus Capital Management, LLC 6.6%
Point72 Asset Management, L.P. 3.9%
Invus Global Management, LLC 3.1%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Forbion Growth Opportunities Fund II Cooperatief U.A.
13D/G
7.3%
$28,343,629
3,452,330 shares
$0 21 Nov 2024
ARMISTICE CAPITAL, LLC
13D/G 13F
Company
6.7%
$14,543,440
3,398,000 shares
$0 30 Jun 2026
Long Focus Capital Management, LLC
13D/G 13F
Company
6.6%
$16,487,221
3,310,687 shares
$0 31 Mar 2026
Point72 Asset Management, L.P.
13D/G 13F
Company
3.9%
$14,882,536
1,860,317 shares
-$15,032,008 30 Jun 2025
Invus Global Management, LLC
13D/G
Raymond Debbane
3.1%
$7,773,192
1,560,882 shares
-$7,909,072 31 Mar 2026
Deep Track Capital, LP
13D/G
2.4%
$9,625,952
1,203,244 shares
-$12,943,416 30 Jun 2025
BAKER BROS. ADVISORS LP
3/4/5 13F
Director, 10%+ Owner · Company
22%
from 13F
$153,412,999
10,056,674 shares
mixed-class rows
02 Jan 2026
FCPM III SERVICES B.V.
13F
Company
13F
6.9%
$14,706,143
3,468,430 shares
30 Jun 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$551,656.

Buys
$0
Insiders: 0
Sells
$551,656
Insiders: 8
Net
-$551,656
Shares: -88,883
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 88,883
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 14,129 $0 $60,461 -$60,461
3-6 0 14,168 $0 $69,977 -$69,977
6-9 0 49,534 $0 $328,256 -$328,256
9-12 0 11,052 $0 $92,962 -$92,962

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-20 of 26 reporting-owner rows connected to BICYCLE THERAPEUTICS PLC. Open a relationship link for the CIK-to-CIK filing trail.

Rows
26
Largest Forms 3/4/5 holder
BAKER BROS. ADVISORS LP
Net 12M change
-$551,656
Latest report
15 Jul 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
BAKER BROS. ADVISORS LP Director, 10%+ Owner $153,412,999 Mixed 02 Jan 2026
Kate Bingham Director $32,731,633 Mixed 13 Jul 2021
Kevin Lee CHIEF EXECUTIVE OFFICER, Director $2,601,822 -$258,045 -9% Filing P/S 02 Jul 2026
Gregory Paul Winter Director $1,390,722 Mixed 02 Jan 2026
Nicholas Keen Chief Scientific Officer $1,355,631 Mixed 03 Jul 2024
Santiago Arroyo Chief Development Officer $973,013 Filing P/S 02 Jan 2025
Alistair Milnes Chief Operating Officer $883,191 -$61,986 -6.6% Filing P/S 02 Jan 2026
Nigel Crockett Chief Business Officer $753,032 Filing P/S 02 Jan 2025
Pierre Legault Director $690,000 Mixed 02 Jan 2025
Michael Skynner Chief Scientific Officer $677,407 -$79,059 -10% Filing P/S 15 Jul 2026
Dominic Smethurst Chief Medical Officer $642,233 Mixed 03 Jan 2023
Richard N. Kender Director $570,860 Mixed 02 Jan 2025
Alethia Young Chief Financial Officer $569,509 -$54,592 -8.7% Filing P/S 02 Jan 2026
Lee Kalowski President and CFO $530,408 Mixed 03 Apr 2023
Michael Charles Ferguson Hannay Chief Prod & Supply Chain Off $406,756 -$56,832 -12% Filing P/S 15 Jul 2026
Jennifer Scott Perry Chief Operating Officer $395,165 -$13,016 -3.2% Filing P/S 15 Jul 2026
Veronica Gh Jordan Director $293,125 Mixed 02 Jan 2024
Travis Alvin Thompson Chief Financial Officer $277,740 -$27,254 -8.9% Filing P/S 15 Jul 2026
Janice Bourque Director $230,103 Mixed 02 Jan 2026
Jose-Carlos Gutierrez-Ramos Director $230,103 Mixed 02 Jan 2026

Recent insider transactions for BICYCLE THERAPEUTICS PLC

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Travis Alvin Thompson BCYC Employee Stock Option (right to buy) Award 60,000 60,000 15 Jul 2026 Direct
Michael Charles Ferguson Hannay BCYC Employee Stock Option (right to buy) Award 60,000 60,000 15 Jul 2026 Direct
Michael Skynner BCYC Employee Stock Option (right to buy) Award 60,000 60,000 15 Jul 2026 Direct
Jennifer Scott Perry BCYC Employee Stock Option (right to buy) Award 60,000 60,000 15 Jul 2026 Direct
Jennifer Scott Perry BCYC Ordinary Shares Sale -0.41% $1,631 $4.34 -376 91,052 06 Jul 2026 Direct
Michael Skynner BCYC Ordinary Shares Sale -0.34% $2,293 $4.31 -532 157,171 06 Jul 2026 Direct
Kevin Lee BCYC Ordinary Shares Sale -0.29% $7,486 $4.31 -1,737 603,671 06 Jul 2026 Direct
Michael Charles Ferguson Hannay BCYC Ordinary Shares Sale -0.27% $1,099 $4.31 -255 94,375 06 Jul 2026 Direct
Travis Alvin Thompson BCYC Ordinary Shares Sale -0.16% $448 $4.31 -104 64,441 06 Jul 2026 Direct
Jennifer Scott Perry BCYC Ordinary Shares Sale -1.12% $4,424 $4.27 -1,036 91,428 02 Jul 2026 Direct
Michael Skynner BCYC Ordinary Shares Sale -1.17% $7,938 $4.27 -1,859 157,703 02 Jul 2026 Direct
Kevin Lee BCYC Ordinary Shares Sale -0.97% $25,214 $4.27 -5,905 605,408 02 Jul 2026 Direct
Michael Charles Ferguson Hannay BCYC Ordinary Shares Sale -1.57% $6,431 $4.27 -1,506 94,630 02 Jul 2026 Direct
Travis Alvin Thompson BCYC Ordinary Shares Sale -1.25% $3,497 $4.27 -819 64,545 02 Jul 2026 Direct
Michael Charles Ferguson Hannay BCYC Ordinary Shares Sale -0.26% $1,268 $5.05 -251 96,136 06 Apr 2026 Direct
Travis Alvin Thompson BCYC Ordinary Shares Sale -0.16% $515 $5.05 -102 65,364 06 Apr 2026 Direct
Jennifer Scott Perry BCYC Ordinary Shares Sale -0.4% $1,865 $5.04 -370 92,464 06 Apr 2026 Direct
Kevin Lee BCYC Ordinary Shares Sale -0.28% $8,666 $5.05 -1,716 611,313 06 Apr 2026 Direct
Michael Skynner BCYC Ordinary Shares Sale -0.33% $2,651 $5.05 -525 159,562 06 Apr 2026 Direct
Michael Charles Ferguson Hannay BCYC Ordinary Shares Sale -1.55% $7,468 $4.91 -1,521 96,387 02 Apr 2026 Direct
Travis Alvin Thompson BCYC Ordinary Shares Sale -1.21% $3,923 $4.91 -799 65,466 02 Apr 2026 Direct
Jennifer Scott Perry BCYC Ordinary Shares Sale -1.11% $5,097 $4.91 -1,038 92,834 02 Apr 2026 Direct
Kevin Lee BCYC Ordinary Shares Sale -0.96% $29,298 $4.91 -5,967 613,029 02 Apr 2026 Direct
Michael Skynner BCYC Ordinary Shares Sale -1.16% $9,226 $4.91 -1,879 160,087 02 Apr 2026 Direct
Travis Alvin Thompson BCYC Employee Stock Option (right to buy) Award 58,000 58,000 03 Feb 2026 Direct
Travis Alvin Thompson BCYC Ordinary Shares Sale -1.65% $7,192 $6.45 -1,115 66,265 05 Jan 2026 Direct
Michael Skynner BCYC Ordinary Shares Sale -1.98% $21,098 $6.46 -3,266 161,966 05 Jan 2026 Direct
Michael Charles Ferguson Hannay BCYC Ordinary Shares Sale -2.36% $15,267 $6.45 -2,367 97,908 05 Jan 2026 Direct
Alistair Milnes BCYC Ordinary Shares Sale -2.44% $22,067 $6.46 -3,416 136,717 05 Jan 2026 Direct
Alethia Young BCYC Ordinary Shares Sale -4.74% $28,123 $6.49 -4,334 87,081 05 Jan 2026 Direct
Kevin Lee BCYC Ordinary Shares Sale -1.74% $70,989 $6.46 -10,989 618,996 05 Jan 2026 Direct
Travis Alvin Thompson BCYC Ordinary Shares Sale -1.92% $8,956 $6.80 -1,317 67,380 02 Jan 2026 Direct
Travis Alvin Thompson BCYC Ordinary Shares Award 120.2% 37,500 68,697 02 Jan 2026 Direct
Travis Alvin Thompson BCYC Employee Stock Option (right to buy) Award 75,000 75,000 02 Jan 2026 Direct
Michael Skynner BCYC Ordinary Shares Sale -1.81% $20,706 $6.80 -3,045 165,232 02 Jan 2026 Direct
Michael Skynner BCYC Ordinary Shares Award 42.3% 50,000 168,277 02 Jan 2026 Direct
Michael Skynner BCYC Employee Stock Option (right to buy) Award 100,000 100,000 02 Jan 2026 Direct
Michael Charles Ferguson Hannay BCYC Ordinary Shares Sale -2.74% $19,224 $6.80 -2,827 100,275 02 Jan 2026 Direct
Michael Charles Ferguson Hannay BCYC Ordinary Shares Award 94.2% 50,000 103,102 02 Jan 2026 Direct
Michael Charles Ferguson Hannay BCYC Employee Stock Option (right to buy) Award 100,000 100,000 02 Jan 2026 Direct
Alistair Milnes BCYC Ordinary Shares Sale -2.26% $22,059 $6.80 -3,244 140,133 02 Jan 2026 Direct
Alistair Milnes BCYC Ordinary Shares Award 53.6% 50,000 143,377 02 Jan 2026 Direct
Alistair Milnes BCYC Employee Stock Option (right to buy) Award 100,000 100,000 02 Jan 2026 Direct
Alethia Young BCYC Ordinary Shares Sale -3.47% $22,365 $6.80 -3,289 91,415 02 Jan 2026 Direct
Alethia Young BCYC Ordinary Shares Award 111.8% 50,000 94,704 02 Jan 2026 Direct
Alethia Young BCYC Employee Stock Option (right to buy) Award 100,000 100,000 02 Jan 2026 Direct
Kevin Lee BCYC Ordinary Shares Sale -1.61% $70,210 $6.80 -10,325 629,985 02 Jan 2026 Direct
Kevin Lee BCYC Ordinary Shares Award 34.7% 165,000 640,310 02 Jan 2026 Direct
Kevin Lee BCYC Employee Stock Option (right to buy) Award 330,000 330,000 02 Jan 2026 Direct
Stephen H. Sands BCYC Ordinary Shares Award 54.6% 9,500 26,893 02 Jan 2026 Direct
* marks a reported price that did not pass the local price check.
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