BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (BCYC)

Q: What does CUSIP 088786108 represent in this 13F holders report?

CUSIP 088786108 is the security identifier for BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share used to aggregate holder disclosures.

Q: How many institutions held BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share in Q3 2021?

67 institutional investors reported BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share for Q3 2021. Use the holders table for investor-level position and value details.

CUSIP: 088786108

Q3 2021 13F Holders as of 30 Sep 2021

Security type / class: Equity / American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share
Total 13F shares: 14,210,499
Total 13F value: $591,072,741
Share change: +1,783,553
Put/Call ratio: 7.2%
SEC-reported price per share: $41.59
Number of holders: 67
Value change: +$80,484,868
Number of buys: 35
Number of sells: 30
Shares outstanding: 50,565,476

Security key

088786108

Report period

Q3 2021

Institutions

Top holders

BCYC full security history Ownership snapshot Full 13F holder table Newer quarter: Q3 2026 BICYCLE THERAPEUTICS PLC SEC filings BICYCLE THERAPEUTICS PLC company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 088786108

Newer quarter: Q3 2026

Recent filing periods:

Q3 2026

Ownership snapshot

Top reported holders of BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

TYBOURNE CAPITAL MANAGEME...

Disclosed value leader

TYBOURNE CAPITAL MANAGEME...

Comparable rows

0/15

Latest evidence

13 Jul 2021

13F 3/4/5 Highest disclosed value: $59,444,000 15 rows are not safely comparable across share classes. Showing 1-6 of 15 holder rows.

Quick read

TYBOURNE CAPITAL MANAGEMENT (HK) LTD has the largest disclosed position value at $59.44M.

0 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens TYBOURNE CAPITAL MANAGEMENT (HK) LTD's linked filing trail.

Disclosed position value Top 5

TYBOURNE CAPITAL MANAGEMENT (HK) LTD $59.44M

SV Health Investors, LLC $58.15M

Janus Henderson Group Ltd. $56.2M

Point72 Asset Management, L.P. $54.83M

EVENTIDE ASSET MANAGEMENT, LLC $35.32M

Value bars compare disclosed positions; verify each figure against the linked filing evidence.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
TYBOURNE CAPITAL MANAGEMENT (HK) LTD	13F Company 13F	— denominator unverified	$59,444,000 1,957,961 shares	—	30 Jun 2021
SV Health Investors, LLC	13F Company 13F	— denominator unverified	$58,147,000 1,915,274 shares	—	30 Jun 2021
Janus Henderson Group Ltd.	13F Company 13F	— denominator unverified	$56,202,000 1,849,720 shares	—	30 Jun 2021
Point72 Asset Management, L.P.	13F Company 13F	— denominator unverified	$54,828,000 1,805,935 shares	—	30 Jun 2021
EVENTIDE ASSET MANAGEMENT, LLC	13F Company 13F	— denominator unverified	$35,323,000 1,163,471 shares	—	30 Jun 2021
Kate Bingham	3/4/5 Director 3/4/5	— denominator unverified	$32,731,633 1,870,379 shares	—	13 Jul 2021

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q3 2021

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

14,210,499

Rows available

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q3 2021 vs Q2 2021 Across Filers

Q2 2021 holders

Q3 2021 holders

Holder diff

Investor	Q2 2021 Shares	Q3 2021 Shares	Share Diff	Share Chg %	Q2 2021 value	Q3 2021 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend