Security key
088786108
BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (BCYC)
CUSIP: 088786108
Q4 2025 13F Holders as of 31 Dec 2025
- Type / Class
- Equity / American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share
- Shares outstanding
- 50,340,741
- Total 13F shares
- 39,173,179
- Share change
- +532,216
- Total reported value
- $277,661,671
- Put/Call ratio
- 37%
- Price per share
- $7.08
- Number of holders
- 108
- Value change
- +$3,442,632
- Number of buys
- 52
- Number of sells
- 40
Report period
Q4 2025
Institutions
108
Top holders
10
BCYC full security history
Newer quarter: Q1 2026
Previous quarter: Q3 2025
BICYCLE THERAPEUTICS PLC SEC filings
BICYCLE THERAPEUTICS PLC company facts
Broader feeds
Reporting periods
Holder history for CUSIP 088786108
Recent filing periods:
Top shareholders of BCYC - BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Forbion Growth Opportunities Fund II Cooperatief U.A. |
13D/G
|
— |
7.3%
|
3,452,330
|
$28,343,629 | $0 | 21 Nov 2024 | |
| Point72 Asset Management, L.P. |
13D/G
13F
|
Company |
3.9%
|
1,860,317
|
$14,882,536 | -$15,032,008 | 30 Jun 2025 | |
| Deep Track Capital, LP |
13D/G
|
— |
2.4%
|
1,203,244
|
$9,625,952 | -$12,943,416 | 30 Jun 2025 | |
| BAKER BROS. ADVISORS LP |
13F
|
Company |
22%
|
10,885,357
|
$84,252,663 | — | 30 Sep 2025 | |
| FCPM III SERVICES B.V. |
13F
|
Company |
6.9%
|
3,452,330
|
$26,721,034 | — | 30 Sep 2025 | |
| ARMISTICE CAPITAL, LLC |
13F
|
Company |
5.9%
|
2,978,000
|
$23,049,720 | — | 30 Sep 2025 | |
| WESTFIELD CAPITAL MANAGEMENT CO LP |
13F
|
Company |
5.9%
|
2,952,543
|
$22,852,683 | — | 30 Sep 2025 | |
| Siren, L.L.C. |
13F
|
Individual |
4%
|
2,012,752
|
$15,578,700 | — | 30 Sep 2025 | |
| Long Focus Capital Management, LLC |
13F
|
Company |
2.8%
|
1,418,695
|
$10,980,699 | — | 30 Sep 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
2.8%
|
1,384,794
|
$10,719,000 | — | 30 Sep 2025 | |
| ACADIAN ASSET MANAGEMENT LLC |
13F
|
Company |
2.6%
|
1,314,556
|
$10,155,000 | — | 30 Sep 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
2.3%
|
1,172,387
|
$9,074,275 | — | 30 Sep 2025 | |
| PRINCIPAL FINANCIAL GROUP INC |
13F
|
Company |
2.3%
|
1,148,402
|
$8,888,631 | — | 30 Sep 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
2.1%
|
1,054,746
|
$8,163,734 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
1.6%
|
822,705
|
$6,367,736 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
1.2%
|
591,535
|
$4,578,482 | — | 30 Sep 2025 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
1%
|
518,700
|
$4,014,738 | — | 30 Sep 2025 | |
| SILVERCREST ASSET MANAGEMENT GROUP LLC |
13F
|
Company |
0.95%
|
476,976
|
$3,691,794 | — | 30 Sep 2025 | |
| Jefferies Financial Group Inc. |
13F
|
Company |
0.8%
|
401,926
|
$3,110,907 | — | 30 Sep 2025 | |
| BlackRock, Inc. |
13F
|
Company |
0.56%
|
282,418
|
$2,185,916 | — | 30 Sep 2025 | |
| Palo Alto Investors LP |
13F
|
Company |
0.44%
|
221,071
|
$1,711,090 | — | 30 Sep 2025 | |
| Legal & General Group Plc |
13F
|
Company |
0.39%
|
197,917
|
$1,531,879 | — | 30 Sep 2025 | |
| PINNACLE ASSOCIATES LTD |
13F
|
Company |
0.39%
|
196,618
|
$1,521,823 | — | 30 Sep 2025 | |
| Eversept Partners, LP |
13F
|
Company |
0.39%
|
194,440
|
$1,504,966 | — | 30 Sep 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.38%
|
189,027
|
$1,463,069 | — | 30 Sep 2025 | |
| PLATINUM INVESTMENT MANAGEMENT LTD |
13F
|
Company |
0.37%
|
184,603
|
$1,428,827 | — | 30 Sep 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
0.37%
|
184,537
|
$1,428,316 | — | 30 Sep 2025 | |
| TD ASSET MANAGEMENT INC |
13F
|
Company |
0.35%
|
178,092
|
$1,378,432 | — | 30 Sep 2025 | |
| TWO SIGMA ADVISERS, LP |
13F
|
Company |
0.31%
|
156,700
|
$1,212,858 | — | 30 Sep 2025 | |
| Birchview Capital, LP |
13F
|
Company |
0.31%
|
154,000
|
$1,191,960 | — | 30 Sep 2025 | |
| Handelsbanken Fonder AB |
13F
|
Company |
0.3%
|
150,000
|
$1,161,000 | — | 30 Sep 2025 | |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
13F
|
Company |
0.28%
|
140,492
|
$1,087,408 | — | 30 Sep 2025 | |
| Rangeley Capital, LLC |
13F
|
Company |
0.26%
|
130,000
|
$1,006,200 | — | 30 Sep 2025 | |
| MOORE CAPITAL MANAGEMENT, LP |
13F
|
Company |
0.25%
|
125,000
|
$967,500 | — | 30 Sep 2025 | |
| Cubist Systematic Strategies, LLC |
13F
|
Company |
0.21%
|
103,410
|
$800,393 | — | 30 Sep 2025 | |
| JANE STREET GROUP, LLC |
13F
|
Company |
0.2%
|
102,459
|
$793,032 | — | 30 Sep 2025 | |
| MONIMUS CAPITAL MANAGEMENT, LP |
13F
|
Company |
0.17%
|
85,224
|
$659,634 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
0.15%
|
74,405
|
$575,895 | — | 30 Sep 2025 | |
| Nan Fung Group Holdings Ltd |
13F
|
Company |
0.14%
|
68,943
|
$533,619 | — | 30 Sep 2025 | |
| DAFNA Capital Management LLC |
13F
|
Company |
0.13%
|
64,492
|
$499,168 | — | 30 Sep 2025 | |
| SEI INVESTMENTS CO |
13F
|
Company |
0.1%
|
49,056
|
$379,693 | — | 30 Sep 2025 | |
| State of Tennessee, Department of Treasury |
13F
|
Company |
0.09%
|
44,842
|
$347,078 | — | 30 Sep 2025 | |
| HARBOR CAPITAL ADVISORS, INC. |
13F
|
Company |
0.08%
|
41,368
|
$320,000 | — | 30 Sep 2025 | |
| Man Group plc |
13F
|
Company |
0.08%
|
40,891
|
$316,496 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.08%
|
39,925
|
$309,019 | — | 30 Sep 2025 | |
| Deutsche Girozentrale DekaBank |
13F
|
Individual |
0.06%
|
30,000
|
$220,000 | — | 30 Sep 2025 | |
| Dynamic Technology Lab Private Ltd |
13F
|
Company |
0.06%
|
27,959
|
$216,000 | — | 30 Sep 2025 | |
| Quadrature Capital Ltd |
13F
|
Company |
0.06%
|
27,894
|
$215,621 | — | 30 Sep 2025 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.05%
|
26,629
|
$206,108 | — | 30 Sep 2025 | |
| ALPS ADVISORS INC |
13F
|
Company |
0.05%
|
24,123
|
$186,712 | — | 30 Sep 2025 |
Institutional Holders of BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (BCYC) as of Q4 2025
As of 31 Dec 2025,
BICYCLE THERAPEUTICS PLC - American Depositary Shares, each representing one ordinary share, nominal value 0.01 euro per share (BCYC) was held by
108 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
39,173,179 shares.
The largest 10 holders included
BAKER BROS. ADVISORS LP, FCPM III SERVICES B.V., ARMISTICE CAPITAL, LLC, WESTFIELD CAPITAL MANAGEMENT CO LP, Siren, L.L.C., ACADIAN ASSET MANAGEMENT LLC, Long Focus Capital Management, LLC, GSK plc, Candriam S.C.A., and PRICE T ROWE ASSOCIATES INC /MD/.
This page lists
108
institutional shareholders reporting positions in this security
for the Q4 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
99
Q4 2025 holders
108
Holder diff
9
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.