Travis Alvin Thompson - 03 Feb 2026 Form 4 Insider Report for BICYCLE THERAPEUTICS PLC (BCYC)

Role: Chief Financial Officer
Signature: /s/ Travis Thompson
Issuer symbol: BCYC
Transactions as of: 03 Feb 2026
Net transactions value: $0
Form type: 4
Filing time: 04 Feb 2026, 19:01:39 UTC
Previous filing: 06 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Thompson Travis Alvin	Chief Financial Officer	C/O BICYCLE THERAPEUTICS PLC, BLOCKS A & B, PORTWAY BUILDING, CAMBRIDGE, UNITED KINGDOM	/s/ Travis Thompson	04 Feb 2026	0001983944

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	BCYC	Employee Stock Option (right to buy)	Award	$0	+58,000		$0.000000	58,000	03 Feb 2026	Ordinary Shares	58,000	$6.49	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This option shall vest with respect to one-fourth (1/4) of the total number of shares underlying the option on February 3, 2027 and the remaining shares in 36 equal monthly installments thereafter.