SEC ownership of Monopar Therapeutics

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001645469.

Comparable stake leader

Janus Henderson Group Ltd.

Disclosed value leader

Janus Henderson Group Ltd.

Comparable rows

26/41

Latest evidence

30 Jun 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
26 of 41
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
Janus Henderson Group Ltd.
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
30 Jun 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001645469
Issuer location
Wilmette, IL

Ownership snapshot

Top shareholders of Monopar Therapeutics (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Janus Henderson Group Ltd.
Disclosed value leader
Janus Henderson Group Ltd.
Comparable rows
26/41
Latest evidence
30 Jun 2026
13D/G 3/4/5 13F Lead comparable stake: 20% 15 rows are not safely comparable across share classes. 13D/G row: Janus Henderson Group Ltd. Showing 1-8 of 41 holder rows.

Quick read

Janus Henderson Group Ltd. leads the comparable SEC ownership view at 20%.

26 of 41 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Janus Henderson Group Ltd.'s linked filing trail.
Comparable ownership Top 5
Janus Henderson Group Ltd. 20%
RA CAPITAL MANAGEMENT, L.P. 9.9%
ASTRAZENECA PLC 7.8%
Adage Capital Management, L.P. 6.2%
Saturn V Capital Management LP 5.2%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 41 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Janus Henderson Group Ltd.
13D/G
JANUS HENDERSON GROUP PLC
20%
$105,138,701
1,287,368 shares
+$9,391,992 30 Sep 2025
RA CAPITAL MANAGEMENT, L.P.
13D/G
9.9%
$43,402,756
667,632 shares
-$4,890,637 31 Dec 2025
ASTRAZENECA PLC
13D/G
7.8%
$34,126,392
522,667 shares
$0 31 Dec 2025
Adage Capital Management, L.P.
13D/G
6.2%
$23,788,856
424,195 shares
-$9,814,000 31 Mar 2026
Saturn V Capital Management LP
13D/G
5.2%
$19,382,706
345,626 shares
$0 05 Jan 2026
Hendricks Diane
3/4/5
10%+ Owner
8.5%
$50,213,802
567,580 shares
16 Dec 2025
Tactic Pharma LLC
3/4/5
10%+ Owner
4.1%
$17,303,519
272,026 shares
-$34,999,957 24 Sep 2025
BlackRock, Inc.
13F
Company
13F
5.2%
$32,297,151
348,819 shares
30 Jun 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$35,238,921.

Buys
$104,925
Insiders: 1
Sells
$35,343,846
Insiders: 2
Net
-$35,238,921
Shares: -553,850
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 1,500 Shares: 555,350
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 0 $0 $0 $0
6-9 1,500 5,121 $104,925 $343,889 -$238,964
9-12 0 550,229 $0 $34,999,957 -$34,999,957

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-18 of 18 reporting-owner rows connected to Monopar Therapeutics. Open a relationship link for the CIK-to-CIK filing trail.

Rows
18
Largest Forms 3/4/5 holder
Hendricks Diane
Net 12M change
-$35,238,921
Latest report
30 Jun 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Hendricks Diane 10%+ Owner $50,213,802 Mixed 16 Dec 2025
Tactic Pharma LLC 10%+ Owner $17,303,519 -$34,999,957 -67% Filing P/S 24 Sep 2025
Chandler Robinson Chief Executive Officer, Director $12,327,369 Mixed 30 Jun 2026
Andrew Cittadine Chief Operating Officer $4,183,501 Mixed 30 Jun 2026
Arthur J. Klausner Director $596,604 -$343,889 -37% Filing P/S 18 Dec 2025
Christopher M. Starr Director $538,894 Mixed 02 Dec 2025
Kim R. Tsuchimoto Director $459,453 Filing P/S 02 Dec 2025
Lavina Talukdar Director $308,022 Mixed 02 Dec 2025
Michael J. Brown Director $136,941 Mixed 31 Dec 2023
Quan Anh Vu Chief Financial Officer $121,688 +$104,925 +626% Mixed 30 Jun 2026
Andrew Paul Mazar Chief Scientific Officer, Director $94,434 Mixed 31 Mar 2022
Karthik Radhakrishnan Chief Financial Officer $10,447 Mixed 28 Oct 2024
TacticGem LLC 10%+ Owner $0 Mixed 09 Dec 2024
Raymond Anderson Director Mixed 02 Dec 2025
Jose Octavio Pinto Costa Filho Chief Medical Officer Mixed 12 Jul 2021
Susan Rodriguez Ccso Mixed 02 Mar 2026
Patrice Rioux Acting Chief Medical Officer Mixed 01 Jan 2026
Nicole Sweeny Director Mixed 26 Jun 2026

Recent insider transactions for Monopar Therapeutics

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Quan Anh Vu MNPR Common Stock Tax liability -18.6% -507 2,221 30 Jun 2026 Direct
Quan Anh Vu MNPR Common Stock Options Exercise 81.9% 1,228 2,728 30 Jun 2026 Direct
Quan Anh Vu MNPR Restricted Stock Unit Options Exercise -12.5% -1,228 8,598 30 Jun 2026 Direct
Chandler Robinson MNPR Common Stock Tax liability -3.95% -4,084 99,267 30 Jun 2026 Direct
Chandler Robinson MNPR Common Stock Options Exercise 14.2% 12,873 103,351 30 Jun 2026 Direct
Chandler Robinson MNPR Restricted Stock Unit Options Exercise -12.1% -12,873 93,403 30 Jun 2026 Direct
Andrew Cittadine MNPR Common Stock Tax liability -3.99% -2,309 55,614 30 Jun 2026 Direct
Andrew Cittadine MNPR Common Stock Options Exercise 9.98% 5,254 57,923 30 Jun 2026 Direct
Andrew Cittadine MNPR Restricted Stock Unit Options Exercise -11.7% -5,254 39,499 30 Jun 2026 Direct
Nicole Sweeny MNPR Stock Options Award 1,284 1,284 26 Jun 2026 Direct
Chandler Robinson MNPR Common Stock Tax liability -2.13% -1,972 90,478 31 Mar 2026 Direct
Chandler Robinson MNPR Common Stock Options Exercise 7.85% 6,732 92,450 31 Mar 2026 Direct
Chandler Robinson MNPR Restricted Stock Unit Options Exercise -5.96% -6,732 106,276 31 Mar 2026 Direct
Andrew Cittadine MNPR Common Stock Tax liability -2.9% -1,571 52,669 31 Mar 2026 Direct
Andrew Cittadine MNPR Common Stock Options Exercise 6.93% 3,514 54,240 31 Mar 2026 Direct
Andrew Cittadine MNPR Restricted Stock Unit Options Exercise -7.28% -3,514 44,753 31 Mar 2026 Direct
Susan Rodriguez MNPR Stock Options Award 48,728 48,728 02 Mar 2026 Direct
Patrice Rioux MNPR Stock Option Award 2,000 2,000 01 Jan 2026 Direct
Chandler Robinson MNPR Common Stock Tax liability -2.9% -2,558 85,718 31 Dec 2025 Direct
Chandler Robinson MNPR Common Stock Options Exercise 11% 8,724 88,276 31 Dec 2025 Direct
Chandler Robinson MNPR Restricted Stock Unit Options Exercise -7.17% -8,724 113,008 31 Dec 2025 Direct
Andrew Cittadine MNPR Common Stock Tax liability -3.59% -1,889 50,726 31 Dec 2025 Direct
Andrew Cittadine MNPR Common Stock Options Exercise 8.96% 4,326 52,615 31 Dec 2025 Direct
Andrew Cittadine MNPR Restricted Stock Unit Options Exercise -8.23% -4,326 48,267 31 Dec 2025 Direct
Quan Anh Vu MNPR Common Stock Purchase $104,925 $69.95 1,500 1,500 26 Dec 2025 Direct
Arthur J. Klausner MNPR Common Stock Sale -36.9% $343,889 $67.15 -5,121 8,762 18 Dec 2025 Direct
Diane Hendricks MNPR Common Stock Other -7.12% -43,499 567,580 16 Dec 2025 See footnote
Arthur J. Klausner MNPR Common Stock Other 124.9% 7,710 13,883 16 Dec 2025 Direct
Andrew Cittadine MNPR Restricted Stock Units Award 36% 13,919 52,593 02 Dec 2025 Direct
Andrew Cittadine MNPR Stock Options Award 8,969 8,969 02 Dec 2025 Direct
Christopher M. Starr MNPR Stock Options Award 2,924 2,924 02 Dec 2025 Direct
Arthur J. Klausner MNPR Stock Options Award 2,924 2,924 02 Dec 2025 Direct
Raymond Anderson MNPR Stock Options Award 2,924 2,924 02 Dec 2025 Direct
Lavina Talukdar MNPR Stock Options Award 2,924 2,924 02 Dec 2025 Direct
Kim R. Tsuchimoto MNPR Stock Options Award 2,924 2,924 02 Dec 2025 Direct
Quan Anh Vu MNPR Restricted Stock Units Award 9,826 9,826 02 Dec 2025 Direct
Quan Anh Vu MNPR Stock Options Award 7,135 7,135 02 Dec 2025 Direct
Chandler Robinson MNPR Restricted Stock Units Award 67.7% 49,133 121,732 02 Dec 2025 Direct
Chandler Robinson MNPR Stock Options Award 16,753 16,753 02 Dec 2025 Direct
Andrew Cittadine MNPR Common Stock Tax liability -3.78% -1,896 48,289 30 Sep 2025 Direct
Andrew Cittadine MNPR Common Stock Options Exercise 9.44% 4,327 50,185 30 Sep 2025 Direct
Andrew Cittadine MNPR Restricted Stock Units Options Exercise -10.1% -4,327 38,674 30 Sep 2025 Direct
Chandler Robinson MNPR Common Stock Tax liability -3.22% -2,646 79,552 30 Sep 2025 Direct
Chandler Robinson MNPR Common Stock Options Exercise 11.9% 8,726 82,198 30 Sep 2025 Direct
Chandler Robinson MNPR Restricted Stock Units Options Exercise -10.7% -8,726 72,599 30 Sep 2025 Direct
Tactic Pharma LLC MNPR Common Stock Sale -66.9% $34,999,957 $63.61 -550,229 272,026 24 Sep 2025 Direct
* marks a reported price that did not pass the local price check.
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