ASTRAZENECA PLC - 31 Dec 2025 SCHEDULE 13G/A Report for Monopar Therapeutics Inc. Common Stock, $0.001 par value per share (MNPR)

Filing Manager: ASTRAZENECA PLC
Reporting Manager: AstraZeneca PLC
Security: Monopar Therapeutics Inc. Common Stock, $0.001 par value per share
Symbol: MNPR
Shares outstanding: 6,700,859 shares
Disclosed Ownership: 522,667 shares
Ownership: 7.8%
Form type: SCHEDULE 13G/A
Filing time: 06 Feb 2026, 09:54:43 UTC
Date of event: 31 Dec 2025
SEC: View on sec.gov

Reporting Managers (2)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
AstraZeneca PLC	7.8%	522,667	522,667	0	/s/ Matthew Bowden	Matthew Bowden / Company Secretary
Alexion Pharmaceuticals, Inc.	7.8%	522,667	522,667	0	/s/ Todd Spalding	Todd Spalding / Secretary