T. Rowe Price Investment Management, Inc.

Holdings History for Karyopharm Therapeutics Inc. - COMMON STOCK (KPTI)

Symbol: KPTI on Nasdaq
Investment type: Equity / COMMON STOCK
Latest Disclosed Shares Owned: 2,244,421 shares
Security Ownership %: 12%

Shares, Excluding Options vs Price

Value, Excluding Options

T. Rowe Price Investment Management, Inc. ownership in Karyopharm Therapeutics Inc. COMMON STOCK (KPTI)

17 Feb 2026 - T. Rowe Price Investment Management, Inc. has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 2,244,421 shares of Karyopharm Therapeutics Inc. COMMON STOCK (KPTI). This represents 12% ownership of the company. In their previous filing dated 07 Nov 2025, T. Rowe Price Investment Management, Inc. had reported owning 2,304,242 shares, indicating a decrease of +2.6%. .

Reporting Name	Ownership %	Change	Value $	Shares owned	Change	Activity %	Price	Form	Report date	Filing time
T. Rowe Price Investment Management, Inc.	12%	-14%	$16,137,387	2,244,421	-59,821	-2.6%	$7.19	13G/A	31 Dec 2025	17 Feb 2026, 10:28
T. Rowe Price Investment Management, Inc.	14%	+68%	$15,073,429	2,304,242	+1,575,476	+216%	$6.54	13G/A	31 Oct 2025	07 Nov 2025, 13:02
T. Rowe Price Investment Management, Inc.	8.4%		$3,315,885	728,766			$4.55	13G	30 Jun 2025	14 Aug 2025, 12:12

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025	0.01%	+0.01%	$10,977,000	1,491,409	+790,417	+113%	$7.36	Q4 2025
30 Sep 2025	0%	-0%	$4,585,000	700,992	-27,774	-3.8%	$6.54	Q3 2025
30 Jun 2025	0%	+0%	$3,141,000	728,766	+589,120	+422%	$4.31	Q2 2025
31 Mar 2025	0%	+0%	$523,000	139,646	+139,646	NEW	$3.75	Q1 2025

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.