Karyopharm Therapeutics Inc. - COMMON STOCK (KPTI)

Q4 2025 13F Holders as of 31 Dec 2025

Type / Class
Equity / COMMON STOCK
Shares outstanding
19,020,517
Total 13F shares
9,456,135
Share change
+6,508,186
Total reported value
$69,598,197
Put/Call ratio
102%
Price per share
$7.36
Number of holders
68
Value change
+$47,945,529
Number of buys
45
Number of sells
14

Institutional Holders of Karyopharm Therapeutics Inc. - COMMON STOCK (KPTI) as of Q4 2025

As of 31 Dec 2025, Karyopharm Therapeutics Inc. - COMMON STOCK (KPTI) was held by 68 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 9,456,135 shares. The largest 10 holders included T. Rowe Price Investment Management, Inc., Opaleye Management Inc., Affinity Asset Advisors, LLC, VANGUARD GROUP INC, Ikarian Capital, LLC, Soleus Capital Management, L.P., ADAGE CAPITAL PARTNERS GP, L.L.C., Davidson Kempner Capital Management LP, BRAIDWELL LP, and Exome Asset Management LLC. This page lists 68 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.