T. Rowe Price Investment Management, Inc. - 31 Oct 2025 SCHEDULE 13G/A Report for KARYOPHARM THERAPEUTICS INC COMMON STOCK (KPTI)

Filing Manager: T. Rowe Price Investment Management, Inc.
Reporting Manager: T. Rowe Price Investment Management, Inc.
Security: KARYOPHARM THERAPEUTICS INC COMMON STOCK
Symbol: KPTI
Shares outstanding: 16.7M shares
Disclosed Ownership: 2.3M shares
Ownership: 13.8%
Form type: SCHEDULE 13G/A
Filing time: 07 Nov 2025, 13:02:38 UTC
Date of event: 31 Oct 2025
Previous filing: 14 Aug 2025
SEC: View on sec.gov

Reporting Managers (1)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
T. Rowe Price Investment Management, Inc.	13.8%	2.3M	704K	0	Ellen York	Vice President