What does CUSIP 48576U205 represent in this 13F holders report?

CUSIP 48576U205 is the security identifier for KPTI - Karyopharm Therapeutics Inc. - Common Stock used to aggregate holder disclosures.

How many institutions held KPTI - Karyopharm Therapeutics Inc. - Common Stock in Q2 2025?

49 institutional investors reported KPTI - Karyopharm Therapeutics Inc. - Common Stock for Q2 2025. Use the holders table for investor-level position and value details.

Karyopharm Therapeutics Inc. - Common Stock (KPTI)

CUSIP: 48576U205

Q2 2025 13F Holders as of 30 Jun 2025

Security type / class: Equity / Common Stock
Total 13F shares: 4,384,748
Total 13F value: $18,898,424
Share change: +1,071,973
Put/Call ratio: 9.3%
SEC-reported price per share: $4.31
Number of holders: 49
Value change: +$4,718,131
Number of buys: 23
Number of sells: 16
Shares outstanding: 22,608,643

Security key

48576U205

Report period

Q2 2025

Institutions

Top holders

KPTI full security history Ownership snapshot Full 13F holder table Karyopharm Therapeutics Inc. SEC filings Karyopharm Therapeutics Inc. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Ownership snapshot

Top reported holders of KPTI - Karyopharm Therapeutics Inc. - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

VANGUARD GROUP INC

Disclosed value leader

VANGUARD GROUP INC

Comparable rows

15/15

Latest evidence

31 Mar 2025

13F Lead comparable stake: 2.3% Showing 1-6 of 15 holder rows.

Quick read

VANGUARD GROUP INC leads the comparable SEC ownership view at 2.3%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens VANGUARD GROUP INC's linked filing trail.

Comparable ownership Top 5

VANGUARD GROUP INC 2.3%

ADAGE CAPITAL PARTNERS GP, L.L.C. 1.9%

Palo Alto Investors LP 1.4%

Eversept Partners, LP 1.1%

BlackRock, Inc. 1.1%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
VANGUARD GROUP INC	13F Company 13F	2.3%	$1,908,499 510,294 shares	—	31 Mar 2025
ADAGE CAPITAL PARTNERS GP, L.L.C.	13F Company 13F	1.9%	$1,575,744 421,322 shares	—	31 Mar 2025
Palo Alto Investors LP	13F Company 13F	1.4%	$1,211,880 324,032 shares	—	31 Mar 2025
Eversept Partners, LP	13F Company 13F	1.1%	$961,756 257,154 shares	—	31 Mar 2025
BlackRock, Inc.	13F Company 13F	1.1%	$907,858 242,742 shares	—	31 Mar 2025
CITADEL ADVISORS LLC	13F Company 13F	0.92%	$773,840 206,909 shares	—	31 Mar 2025

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q2 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

4,384,748

Rows available

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q2 2025 vs Q1 2025 Across Filers

Q1 2025 holders

Q2 2025 holders

Holder diff

Investor	Q1 2025 Shares	Q2 2025 Shares	Share Diff	Share Chg %	Q1 2025 value	Q2 2025 value	Value change	Value Chg %