JANUS HENDERSON GROUP PLC

Holdings History for Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share (GPCR)

Symbol: GPCR on Nasdaq
Investment type: Equity / Ordinary Shares, par value $0.0001 per share
Latest Disclosed Shares Owned: 4,448,826 shares
Security Ownership %: 7.7%

Shares, Excluding Options vs Price

Value, Excluding Options

JANUS HENDERSON GROUP PLC ownership in Structure Therapeutics Inc. Ordinary Shares, par value $0.0001 per share (GPCR)

14 Nov 2025 - JANUS HENDERSON GROUP PLC has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 4,448,826 shares of Structure Therapeutics Inc. Ordinary Shares, par value $0.0001 per share (GPCR). This represents 7.7% ownership of the company. In their previous filing dated 14 Aug 2025, JANUS HENDERSON GROUP PLC had reported owning 4,573,006 shares, indicating a decrease of +2.7%. .

Reporting Name	Ownership %	Change	Value $	Shares owned	Change	Activity %	Price	Form	Report date	Filing time
JANUS HENDERSON GROUP PLC	7.7%	-3.8%	$124,567,128	4,448,826	-124,180	-2.7%	$28.00	13G/A	30 Sep 2025	14 Nov 2025, 12:07
JANUS HENDERSON GROUP PLC	8%	+5%	$85,698,132	4,573,006	+217,560	+5%	$18.74	13G/A	30 Jun 2025	14 Aug 2025, 11:26
JANUS HENDERSON GROUP PLC	7.6%	+4.3%	$112,849,606	4,355,446	+195,558	+4.7%	$25.91	13G/A	31 Mar 2025	14 May 2025, 12:32
JANUS HENDERSON GROUP PLC	7.3%		$107,782,698	4,159,888			$25.91	13G/A	31 Dec 2024	14 Feb 2025, 12:22

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025	0.16%	+0.02%	$354,005,522	5,090,148	+641,322	+14%	$69.55	Q4 2025
30 Sep 2025	0.06%	-0%	$124,603,170	4,448,826	-124,180	-2.7%	$28.01	Q3 2025
30 Jun 2025	0.05%	+0%	$94,948,256	4,573,006	+217,812	+5%	$20.76	Q2 2025
31 Mar 2025	0.05%	+0%	$86,126,811	4,355,194	+195,306		$19.78	Q1 2025
31 Dec 2024	0.06%	+0%	$112,816,163	4,159,888	+203,010	+5.1%	$27.12	Q4 2024
30 Sep 2024	0.09%	+0.01%	$173,623,444	3,956,878	+602,609	+18%	$43.88	Q3 2024
30 Jun 2024	0.07%	+0.03%	$131,649,761	3,354,269	+1,277,569	+62%	$39.25	Q2 2024
31 Mar 2024	0.05%	+0.01%	$88,994,120	2,076,700	+532,284	+34%	$42.85	Q1 2024
31 Dec 2023	0.04%	-0.01%	$62,838,123	1,544,416	-546,907	-26%	$40.69	Q4 2023
30 Sep 2023	0.06%	+0.06%	$97,499,156	2,091,323	+2,013,893	+2601%	$46.62	Q3 2023
30 Jun 2023	0%	+0%	$3,218,378	77,430	+70,343	+993%	$41.57	Q2 2023
31 Mar 2023		0%	$3,123,368	339,334	0		$9.20 ^*	Q1 2023
31 Mar 2023	0%	+0%	$166,438	7,087	+7,087	NEW	$23.48	Q1 2023

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.