Security key
86366E106
Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share (GPCR)
CUSIP: 86366E106
Q4 2025 13F Holders as of 31 Dec 2025
- Security type / class
- Equity / Ordinary Shares, par value $0.0001 per share
- Total 13F shares
- 65,776,439
- Total 13F value
- $4,580,197,295
- Share change
- +9,022,085
- Put/Call ratio
- 27%
- SEC-reported price per share
- $69.55
- Number of holders
- 197
- Value change
- +$791,360,837
- Number of buys
- 115
- Number of sells
- 88
- Shares outstanding
- 213,001,347
Holder snapshot
7 signals
Open additional details 1 more signal available
Security identity
Names, identifiers, and filing context for this profile.
1 source field
Report period
Q4 2025
Institutions
197
Top holders
10
GPCR full security history
Ownership snapshot
Full 13F holder table
Newer quarter: Q1 2026
Previous quarter: Q3 2025
Structure Therapeutics Inc. SEC filings
Structure Therapeutics Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 86366E106
Recent filing periods:
Ownership snapshot
Top reported holders of GPCR - Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
FMR LLC
Disclosed value leader
FMR LLC
Comparable rows
15/15
Latest evidence
31 Dec 2025
13D/G
13F
Lead comparable stake: 15%
13D/G row: FMR LLC
Showing 1-6 of 15 holder rows.
Quick read
FMR LLC leads the comparable SEC ownership view at 15%.
15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens FMR LLC's linked filing trail.
Comparable ownership
Top 5
FMR LLC
15%
WELLINGTON MANAGEMENT GROUP LLP
10%
Avoro Capital Advisors LLC
9.4%
JANUS HENDERSON GROUP PLC
7.7%
Deep Track Capital, LP
6%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-6 of 15 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| FMR LLC |
13D/G
13F
Company
|
15%
|
$2,163,883,695
31,112,634 shares
|
+$776,609,280 | 31 Dec 2025 |
| WELLINGTON MANAGEMENT GROUP LLP |
13D/G
13F
Company
|
10%
|
$1,481,942,431
21,365,952 shares
|
+$50,941,729 | 31 Dec 2025 |
| Avoro Capital Advisors LLC |
13D/G
13F
Company
|
9.4%
|
$454,066,620
16,216,665 shares
|
$0 | 30 Sep 2025 |
| JANUS HENDERSON GROUP PLC |
13F
13D/G
Company
|
7.7%
from 13D/G
|
$124,603,170
4,448,826 shares
|
— | 30 Sep 2025 |
| Deep Track Capital, LP |
13D/G
13F
Company
|
6%
|
$855,579,599
12,335,346 shares
|
-$21,646,354 | 31 Dec 2025 |
| BIOTECHNOLOGY VALUE FUND L P |
13D/G
BVF PARTNERS L P/IL
|
4.9%
|
$723,914,898
10,437,066 shares
|
+$57,243,848 | 31 Dec 2025 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
13F holder rows
Institutional holders as of Q4 2025
Investor-level positions for this CUSIP, loaded as an interactive table.
Institutions
197
Shares
65,776,439
Rows available
197
| Investor | Option | Weight % | Change % | SEC-reported value | * Price | Shares | Share Change | Activity | Report Period |
|---|
* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
155
Q4 2025 holders
197
Holder diff
42
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 value | Q4 2025 value | Value change | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend