Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share (GPCR)
CUSIP: 86366E106
Q3 2025 13F Holders as of 30 Sep 2025
- Type / Class
- Equity / Ordinary Shares, par value $0.0001 per share
- Shares outstanding
- 213,001,347
- Total 13F shares
- 56,638,847
- Share change
- +1,976,064
- Total reported value
- $1,582,549,935
- Put/Call ratio
- 68%
- Price per share
- $28.00
- Number of holders
- 155
- Value change
- +$86,587,271
- Number of buys
- 78
- Number of sells
- 85
Quarterly Holders Quick Answers
What is CUSIP 86366E106?
CUSIP 86366E106 identifies GPCR - Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share in SEC institutional holdings data.
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Recent filing periods for CUSIP 86366E106:
Top shareholders of GPCR - Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Avoro Capital Advisors LLC |
13D/G
|
— |
9.4%
|
16,216,665
|
$454,066,620 | $0 | 30 Sep 2025 | |
| Capital Research Global Investors |
13D/G
|
— |
3.8%
|
6,492,435
|
$168,218,991 | $0 | 31 Mar 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
3.2%
|
6,875,769
|
$142,603,450 | — | 30 Jun 2025 | |
| JANUS HENDERSON GROUP PLC |
13D/G
13F
|
Company |
7.7%
|
4,448,826
|
$124,567,128 | -$3,477,040 | 30 Sep 2025 | |
| Deep Track Capital, LP |
13F
|
Company |
2.4%
|
5,133,917
|
$106,477,439 | — | 30 Jun 2025 | |
| FMR LLC |
13F
|
Company |
2.3%
|
4,914,965
|
$101,936,374 | — | 30 Jun 2025 | |
| BAKER BROS. ADVISORS LP |
13F
|
Company |
1.2%
|
2,508,767
|
$52,031,828 | — | 30 Jun 2025 | |
| BVF INC/IL |
13F
|
Company |
0.83%
|
1,771,417
|
$36,739,189 | — | 30 Jun 2025 | |
| Capital International Investors |
13F
|
Company |
0.76%
|
1,618,876
|
$33,575,488 | — | 30 Jun 2025 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.75%
|
1,588,198
|
$32,939,228 | — | 30 Jun 2025 | |
| RA CAPITAL MANAGEMENT, L.P. |
13F
|
Company |
0.71%
|
1,517,418
|
$31,471,249 | — | 30 Jun 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.62%
|
1,328,479
|
$27,552,655 | — | 30 Jun 2025 | |
| Casdin Capital, LLC |
13F
|
Company |
0.58%
|
1,225,000
|
$25,406,500 | — | 30 Jun 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.57%
|
1,220,055
|
$25,303,941 | — | 30 Jun 2025 | |
| Vestal Point Capital, LP |
13F
|
Company |
0.56%
|
1,200,000
|
$24,888,000 | — | 30 Jun 2025 | |
| ORBIMED ADVISORS LLC |
13F
|
Company |
0.56%
|
1,199,300
|
$24,873,482 | — | 30 Jun 2025 | |
| Rock Springs Capital Management LP |
13F
|
Company |
0.53%
|
1,135,879
|
$23,558,130 | — | 30 Jun 2025 | |
| TCG Crossover Management, LLC |
13F
|
Company |
0.5%
|
1,063,000
|
$22,046,620 | — | 30 Jun 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.43%
|
917,346
|
$19,025,767 | — | 30 Jun 2025 | |
| PRINCIPAL FINANCIAL GROUP INC |
13F
|
Company |
0.4%
|
853,202
|
$17,695,410 | — | 30 Jun 2025 | |
| Logos Global Management LP |
13F
|
Company |
0.4%
|
850,000
|
$17,629,000 | — | 30 Jun 2025 | |
| Ramy Farid |
3/4/5
|
Director |
—
mixed-class rows
|
3,535,495
mixed-class rows
|
$17,176,500 | — | 07 Feb 2023 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.35%
|
741,783
|
$15,384,575 | — | 30 Jun 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.32%
|
672,792
|
$13,953,706 | — | 30 Jun 2025 | |
| Catalio Capital Management, LP |
13F
|
Company |
0.31%
|
670,575
|
$13,907,725 | — | 30 Jun 2025 | |
| AMERICAN CENTURY COMPANIES INC |
13F
|
Company |
0.23%
|
491,193
|
$10,187,457 | — | 30 Jun 2025 | |
| FEDERATED HERMES, INC. |
13F
|
Company |
0.22%
|
468,300
|
$9,712,542 | — | 30 Jun 2025 | |
| PACIFIC HEIGHTS ASSET MANAGEMENT LLC |
13F
|
Company |
0.22%
|
460,000
|
$9,540,400 | — | 30 Jun 2025 | |
| Monashee Investment Management LLC |
13F
|
Company |
0.2%
|
430,000
|
$8,918,200 | — | 30 Jun 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.2%
|
424,548
|
$8,805,125 | — | 30 Jun 2025 | |
| Aberdeen Group plc |
13F
|
Company |
0.19%
|
401,624
|
$8,329,682 | — | 30 Jun 2025 | |
| Handelsbanken Fonder AB |
13F
|
Company |
0.18%
|
380,000
|
$7,881,000 | — | 30 Jun 2025 | |
| DEERFIELD MANAGEMENT COMPANY, L.P. |
13F
|
Company |
0.18%
|
373,407
|
$7,744,461 | — | 30 Jun 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
0.17%
|
352,868
|
$7,319,000 | — | 30 Jun 2025 | |
| Bellevue Group AG |
13F
|
Company |
0.16%
|
348,527
|
$7,228,450 | — | 30 Jun 2025 | |
| Point72 Asset Management, L.P. |
13F
|
Company |
0.15%
|
330,000
|
$6,844,200 | — | 30 Jun 2025 | |
| Schonfeld Strategic Advisors LLC |
13F
|
Company |
0.15%
|
321,591
|
$6,669,795 | — | 30 Jun 2025 | |
| ArrowMark Colorado Holdings LLC |
13F
|
Company |
0.14%
|
298,937
|
$6,199,953 | — | 30 Jun 2025 | |
| HSG Holding Ltd |
13F
|
Company |
0.12%
|
266,062
|
$5,518,126 | — | 30 Jun 2025 | |
| BlackRock, Inc. |
13F
|
Company |
0.11%
|
243,334
|
$5,046,747 | — | 30 Jun 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.1%
|
220,174
|
$4,566,409 | — | 30 Jun 2025 | |
| Foresite Capital Management VI LLC |
13F
|
Company |
0.1%
|
210,000
|
$4,355,400 | — | 30 Jun 2025 | |
| Pier Capital, LLC |
13F
|
Company |
0.09%
|
198,478
|
$4,116,434 | — | 30 Jun 2025 | |
| Ikarian Capital, LLC |
13F
|
Company |
0.09%
|
183,085
|
$3,797,183 | — | 30 Jun 2025 | |
| READYSTATE ASSET MANAGEMENT LP |
13F
|
Company |
0.08%
|
178,612
|
$3,704,413 | — | 30 Jun 2025 | |
| Woodline Partners LP |
13F
|
Company |
0.08%
|
176,453
|
$3,659,635 | — | 30 Jun 2025 | |
| MARSHALL WACE, LLP |
13F
|
Company |
0.08%
|
176,060
|
$3,651,486 | — | 30 Jun 2025 | |
| SILVERARC CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.08%
|
175,636
|
$3,642,691 | — | 30 Jun 2025 | |
| Nantahala Capital Management, LLC |
13F
|
Company |
0.08%
|
168,553
|
$3,495,789 | — | 30 Jun 2025 | |
| CANADA PENSION PLAN INVESTMENT BOARD |
13F
|
Company |
0.08%
|
167,800
|
$3,480,172 | — | 30 Jun 2025 |
Institutional Holders of Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share (GPCR) as of Q3 2025
As of 30 Sep 2025,
Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share (GPCR) was held by
155 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
56,638,847 shares.
The largest 10 holders included
WELLINGTON MANAGEMENT GROUP LLP, FMR LLC, Avoro Capital Advisors LLC, JANUS HENDERSON GROUP PLC, Deep Track Capital, LP, BVF INC/IL, BAKER BROS. ADVISORS LP, Casdin Capital, LLC, RA CAPITAL MANAGEMENT, L.P., and MILLENNIUM MANAGEMENT LLC.
This page lists
155
institutional shareholders reporting positions in this security
for the Q3 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q3 2025 vs Q2 2025 Across Filers
Q2 2025 holders
172
Q3 2025 holders
155
Holder diff
-17
| Investor | Q2 2025 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q2 2025 Value $ | Q3 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.