Security Snapshot

Structure Therapeutics Inc. - COMMON STOCK (GPCR) Institutional Ownership

CUSIP: 86366E106

13F Institutional Holders and Ownership History from Q1 2023 to Q2 2026

Latest Period

Q2 2026

Institutions Reporting

192

Shares (Excl. Options)

67,559,599

Price

$53.67

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Latest holder snapshot 5 signals
Portfolio coverage rank
0.01%
Share change
+987,093
Value change
+$65,031,904
Number of holders
192
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
213,616,432
SEC-reported price per share
$46.03
Insider filing price
$46.03
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • GPCR - Structure Therapeutics Inc. - COMMON STOCK is tracked under CUSIP 86366E106.
  • 192 institutions reported positions in Q2 2026.
  • 7 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 195 to 192 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from $3,215,748,317 to $3,622,549,992.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 192 institutions filings for Q2 2026.

Open SEC evidence

Security key

86366E106

Latest holder period

Q2 2026

13F holders

192

13D/G owners

7

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
7
Security
GPCR
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
FMR LLC 13% -12% $1,554,802,927 -$160,747,712 28,197,369 -9.4% FMR LLC 30 Jun 2026
WELLINGTON MANAGEMENT GROUP LLP 10% -15% $1,481,942,431 +$50,941,729 21,365,952 +3.6% Wellington Management Group LLP 31 Dec 2025
Avoro Capital Advisors LLC 9.4% $454,066,620 16,216,665 Avoro Capital Advisors LLC 30 Sep 2025
Deep Track Capital, LP 6% -20% $855,579,599 -$21,646,354 12,335,346 -2.5% Deep Track Capital, LP 31 Dec 2025
BIOTECHNOLOGY VALUE FUND L P 4.9% -12% $723,914,898 +$57,243,848 10,437,066 +8.6% BVF PARTNERS L P/IL 31 Dec 2025
Capital Research Global Investors 3.8% $168,218,991 6,492,435 Capital Research Global Investors 31 Mar 2025
JANUS HENDERSON GROUP PLC 7.7% -3.8% $124,567,128 -$3,477,040 4,448,826 -2.7% JANUS HENDERSON GROUP PLC 30 Sep 2025

As of 30 Jun 2026, 192 institutional investors reported holding 67,559,599 shares of Structure Therapeutics Inc. - COMMON STOCK (GPCR). This represents 32% of the company’s total 213,616,432 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
27%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
FMR LLC 3.7% 7,810,306 -7.1% 0.02% $419,179,123
WELLINGTON MANAGEMENT GROUP LLP 3.5% 7,379,433 +1.6% 0.07% $396,054,169
Avoro Capital Advisors LLC 3.1% 6,555,555 0% 3.2% $351,836,637
Jupiter Topco LLC 2.4% 5,204,212 0% 0.11% $279,339,383
Deep Track Capital, LP 2.2% 4,740,072 +11% 3.7% $254,399,664
BVF INC/IL 1.6% 3,366,823 -2.7% 4.6% $180,697,390
MORGAN STANLEY 1.3% 2,806,640 +22% 0.01% $150,632,372
ORBIMED ADVISORS LLC 1% 2,209,400 +50% 2.2% $118,578,498
PRINCIPAL FINANCIAL GROUP INC 0.82% 1,752,753 -0.06% 0.05% $94,070,254
AMERICAN CENTURY COMPANIES INC 0.79% 1,682,179 +17% 0.04% $90,282,956
RTW INVESTMENTS, LP 0.75% 1,607,507 0.74% $86,274,901
Driehaus Capital Management LLC 0.73% 1,553,219 -1.5% 0.48% $83,361,264
BAKER BROS. ADVISORS LP 0.67% 1,432,529 0% 0.39% $76,883,831
Casdin Capital, LLC 0.55% 1,175,000 0% 3.2% $63,062,250
DEERFIELD MANAGEMENT COMPANY, L.P. 0.51% 1,086,000 +41% 0.61% $58,285,620
CAPITOLIS LIQUID GLOBAL MARKETS LLC 0.49% 1,041,100 -9.6% 0.24% $55,875,837
Siren, L.L.C. 0.41% 872,967 -34% 0.95% $46,852,139
PRICE T ROWE ASSOCIATES INC /MD/ 0.4% 845,532 -58% 0% $45,380,000
Pacific Heights Asset Management LLC 0.37% 800,000 +6.7% 1.4% $42,936,000
Rock Springs Capital Management LP 0.3% 640,317 +0.02% 1.7% $34,365,813
Aberdeen Group plc 0.3% 639,915 +63% 0.05% $34,344,238
ALLIANCEBERNSTEIN L.P. 0.29% 611,708 -4.2% 0.01% $29,484,326
FRANKLIN RESOURCES INC 0.27% 578,839 +8.9% 0.01% $31,066,308
BANK OF AMERICA CORP /DE/ 0.26% 563,422 +148% 0% $30,238,858
BlackRock, Inc. 0.24% 511,149 +16% 0% $27,433,368

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
14
Latest
Q2 2026
Rows shown
1-14 of 14
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 67,559,599 $3,622,549,992 +$65,031,904 $53.67 192
2026 Q1 66,450,436 $3,215,748,317 -$49,596,066 $48.20 195
2025 Q4 65,776,439 $4,580,197,295 +$791,360,837 $69.55 197
2025 Q3 56,638,847 $1,582,549,935 +$86,587,271 $28.00 155
2025 Q2 54,653,188 $1,133,630,623 -$12,998,783 $20.74 172
2025 Q1 55,933,663 $980,564,651 -$97,541,400 $17.31 150
2024 Q4 60,660,143 $1,645,431,741 -$123,990,833 $27.12 162
2024 Q3 61,353,442 $2,685,754,151 +$108,882,886 $43.89 160
2024 Q2 59,255,636 $2,326,748,242 +$609,713,327 $39.27 164
2024 Q1 43,607,566 $1,861,796,908 +$49,174,094 $42.86 119
2023 Q4 42,586,066 $1,736,374,072 +$365,354,803 $40.76 121
2023 Q3 32,752,287 $1,641,782,565 +$750,250,715 $50.42 83
2023 Q2 17,647,287 $699,362,453 +$105,685,176 $41.57 48
2023 Q1 14,419,544 $343,038,725 +$343,038,726 $23.79 38
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