Latest Period
Q1 2026
Security Snapshot
Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share (GPCR) Institutional Ownership
CUSIP: 86366E106
13F Institutional Holders and Ownership History from Q1 2023 to Q1 2026
Institutions Reporting
194
Shares (Excl. Options)
66,450,352
Price
$48.20
Save this security page for your next review
Keep this CUSIP in your watchlists so you can revisit quarter changes from one place. If you create an account from here, we will bring you back after verification.
- Security type / class
- Equity / Ordinary Shares, par value $0.0001 per share
- Symbol
- GPCR on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 66,450,352
- Total 13F value
- $3,215,744,268
- Portfolio coverage rank
- 0.01%
- Share change
- +327,719
- Value change
- -$49,600,115
- Number of holders
- 194
- Shares outstanding
- 213,001,347
- SEC-reported price per share
- $39.19
- Insider filing price
- $39.19
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- GPCR - Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share is tracked under CUSIP 86366E106.
- 194 institutions reported positions in Q1 2026.
- 7 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 197 to 194 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $4,580,197,295 to $3,215,744,268.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 194 institutions filings for Q1 2026.
Security key
86366E106
Latest holder period
Q1 2026
13F holders
194
13D/G owners
7
CIK / CUSIP context first
Open Q1 2026 holders
GPCR full holder history
Structure Therapeutics Inc. SEC filings
Structure Therapeutics Inc. company facts
Structure Therapeutics Inc. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 86366E106:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
7
Security
GPCR
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| FMR LLC | 15% | +28% | $2,163,883,695 | +$776,609,280 | 31,112,634 | +56% | FMR LLC | 31 Dec 2025 |
| WELLINGTON MANAGEMENT GROUP LLP | 10% | -15% | $1,481,942,431 | +$50,941,729 | 21,365,952 | +3.6% | Wellington Management Group LLP | 31 Dec 2025 |
| Avoro Capital Advisors LLC | 9.4% | $454,066,620 | 16,216,665 | Avoro Capital Advisors LLC | 30 Sep 2025 | |||
| Deep Track Capital, LP | 6% | -20% | $855,579,599 | -$21,646,354 | 12,335,346 | -2.5% | Deep Track Capital, LP | 31 Dec 2025 |
| BIOTECHNOLOGY VALUE FUND L P | 4.9% | -12% | $723,914,898 | +$57,243,848 | 10,437,066 | +8.6% | BVF PARTNERS L P/IL | 31 Dec 2025 |
| Capital Research Global Investors | 3.8% | $168,218,991 | 6,492,435 | Capital Research Global Investors | 31 Mar 2025 | |||
| JANUS HENDERSON GROUP PLC | 7.7% | -3.8% | $124,567,128 | -$3,477,040 | 4,448,826 | -2.7% | JANUS HENDERSON GROUP PLC | 30 Sep 2025 |
As of 31 Mar 2026, 194 institutional investors reported holding 66,450,352 shares of Structure Therapeutics Inc. - Ordinary Shares, par value $0.0001 per share (GPCR). This represents 31% of the company’s total 213,001,347 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
26%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 3.9% | 8,403,449 | -3.5% | 0.02% | $405,046,242 |
| WELLINGTON MANAGEMENT GROUP LLP | 3.4% | 7,260,287 | +1.9% | 0.07% | $349,945,833 |
| Avoro Capital Advisors LLC | 3.1% | 6,555,555 | 0% | 3.1% | $315,977,751 |
| JANUS HENDERSON GROUP PLC | 2.5% | 5,354,981 | +5.2% | 0.12% | $258,260,143 |
| Deep Track Capital, LP | 2% | 4,279,848 | +4.1% | 4.3% | $206,288,674 |
| BVF INC/IL | 1.6% | 3,459,358 | -0.57% | 5.3% | $166,741,056 |
| MORGAN STANLEY | 1.1% | 2,305,457 | +10% | 0.01% | $111,123,045 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 0.94% | 2,000,696 | +20% | 0.01% | $96,434,000 |
| PRINCIPAL FINANCIAL GROUP INC | 0.82% | 1,753,764 | +37% | 0.05% | $84,531,425 |
| Driehaus Capital Management LLC | 0.74% | 1,577,356 | -4% | 0.56% | $76,028,559 |
| ORBIMED ADVISORS LLC | 0.69% | 1,475,403 | +27% | 1.6% | $71,114,425 |
| AMERICAN CENTURY COMPANIES INC | 0.68% | 1,438,031 | +184% | 0.04% | $69,313,416 |
| BAKER BROS. ADVISORS LP | 0.67% | 1,432,529 | 0% | 0.4% | $69,047,898 |
| Siren, L.L.C. | 0.62% | 1,328,698 | +23% | 1.8% | $64,043,244 |
| Casdin Capital, LLC | 0.55% | 1,175,000 | 0% | 4.3% | $56,635,000 |
| CAPITOLIS LIQUID GLOBAL MARKETS LLC | 0.54% | 1,151,300 | 0% | 0.35% | $55,492,660 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 0.36% | 767,993 | 0% | 0.44% | $37,017,263 |
| Pacific Heights Asset Management LLC | 0.35% | 750,000 | +7.1% | 1.2% | $36,150,000 |
| Rock Springs Capital Management LP | 0.3% | 640,217 | -14% | 1.8% | $30,858,459 |
| ALLIANCEBERNSTEIN L.P. | 0.3% | 638,813 | -25% | 0.01% | $44,429,444 |
| Paradigm Biocapital Advisors LP | 0.26% | 545,287 | 0.54% | $26,282,833 | |
| FRANKLIN RESOURCES INC | 0.25% | 531,595 | -39% | 0.01% | $25,622,876 |
| Logos Global Management LP | 0.23% | 500,000 | -17% | 1.2% | $24,100,000 |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 0.22% | 467,800 | 0% | 0.04% | $22,547,960 |
| BlackRock, Inc. | 0.21% | 441,975 | +2.8% | 0% | $21,303,196 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
13
Latest
Q1 2026
Rows shown
1-13 of 13
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 66,450,352 | $3,215,744,268 | -$49,600,115 | $48.20 | 194 |
| 2025 Q4 | 65,776,439 | $4,580,197,295 | +$791,360,837 | $69.55 | 197 |
| 2025 Q3 | 56,638,847 | $1,582,549,935 | +$86,587,271 | $28.00 | 155 |
| 2025 Q2 | 54,653,188 | $1,133,630,623 | -$12,998,783 | $20.74 | 172 |
| 2025 Q1 | 55,933,663 | $980,564,651 | -$97,541,400 | $17.31 | 150 |
| 2024 Q4 | 60,660,143 | $1,645,431,741 | -$123,990,833 | $27.12 | 162 |
| 2024 Q3 | 61,353,442 | $2,685,754,151 | +$108,882,886 | $43.89 | 160 |
| 2024 Q2 | 59,255,636 | $2,326,748,242 | +$609,713,327 | $39.27 | 164 |
| 2024 Q1 | 43,607,566 | $1,861,796,908 | +$49,174,094 | $42.86 | 119 |
| 2023 Q4 | 42,586,066 | $1,736,374,072 | +$365,354,803 | $40.76 | 121 |
| 2023 Q3 | 32,752,287 | $1,641,782,565 | +$750,250,715 | $50.42 | 83 |
| 2023 Q2 | 17,647,287 | $699,362,453 | +$105,685,176 | $41.57 | 48 |
| 2023 Q1 | 14,419,544 | $343,038,725 | +$343,038,726 | $23.79 | 38 |