BAKER BROS. ADVISORS LP

Holdings History for MADRIGAL PHARMACEUTICALS, INC. - COM (MDGL)

Symbol: MDGL on Nasdaq
Investment type: Equity - Shares of Stock
Class: COM

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
9/30/2024	4.34%		$419M	1.97M			$212.22	Q3 2024
6/30/2024	7.07%	+0.02%	$553M	1.97M	+4,792	+0.24%	$280.16	Q2 2024
3/31/2024	6.6%		$526M	1.97M			$267.04	Q1 2024
12/31/2023	5.19%	+1.12%	$456M	1.97M	+424,685	+27.5%	$231.38	Q4 2023
9/30/2023	1.3%		$226M	1.55M			$146.04	Q3 2023
6/30/2023	2.07%		$357M	1.55M			$231.00	Q2 2023
3/31/2023	2.04%		$374M	1.55M			$242.26	Q1 2023
12/31/2022	2.69%	+0.08%	$448M	1.55M	+45,900	+3.06%	$290.25	Q4 2022
9/30/2022	0.64%		$97.4M	1.5M			$64.99	Q3 2022
6/30/2022	0.61%		$107M	1.5M			$71.58	Q2 2022
3/31/2022	0.85%		$147M	1.5M			$98.12	Q1 2022
12/31/2021	0.62%		$127M	1.5M			$84.74	Q4 2021
9/30/2021	0.53%		$120M	1.5M			$79.79	Q3 2021
6/30/2021	0.64%		$146M	1.5M			$97.41	Q2 2021
3/31/2021	0.76%		$175M	1.5M			$116.97	Q1 2021
12/31/2020	0.63%		$167M	1.5M			$111.17	Q4 2020
9/30/2020	0.71%		$178M	1.5M	+1	+0%	$118.73	Q3 2020
6/30/2020	0.75%		$170M	1.5M			$113.25	Q2 2020
3/31/2020	0.62%	+0.14%	$100M	1.5M	+329,934	+28.2%	$66.76	Q1 2020
12/31/2019	0.57%		$107M	1.17M			$91.11	Q4 2019
9/30/2019	0.69%		$101M	1.17M			$86.22	Q3 2019
6/30/2019	0.83%		$123M	1.17M			$104.81	Q2 2019
3/31/2019	0.94%		$146M	1.17M			$125.26	Q1 2019
12/31/2018	1.08%		$132M	1.17M			$112.72	Q4 2018
9/30/2018	1.65%		$250M	1.17M			$214.13	Q3 2018
6/30/2018	2.46%	+1.16%	$327M	1.17M	+553,594	+89.9%	$279.69	Q2 2018
3/31/2018	0.61%		$71.9M	616K			$116.79	Q1 2018
12/31/2017	0.49%	+0.44%	$56.5M	616K	+557,922	+966%	$91.79	Q4 2017
9/30/2017	0.02%		$2.6M	57.8K			$44.98	Q3 2017
6/30/2017	0.01%		$939K	57.8K			$16.26	Q2 2017
3/31/2017	0.01%		$890K	57.8K			$15.41	Q1 2017
12/31/2016	0.01%		$861K	57.8K			$14.91	Q4 2016
9/30/2016	0.01%	+0.01%	$732K	57.8K	+57,762	NEW	$12.67	Q3 2016

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.