Latest Period
Q1 2026
Security Snapshot
MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share (MDGL) Institutional Ownership
CUSIP: 558868105
13F Institutional Holders and Ownership History from Q2 2016 to Q1 2026
Institutions Reporting
373
Shares (Excl. Options)
23,773,052
Price
$523.47
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- Security type / class
- Equity / Common Stock, $0.0001 par value per share
- Symbol
- MDGL on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 23,773,052
- Total 13F value
- $12,441,414,030
- Portfolio coverage rank
- 0.01%
- Share change
- +207,571
- Value change
- +$74,301,029
- Number of holders
- 373
- Shares outstanding
- 22,822,754
- SEC-reported price per share
- $517.26
- Insider filing price
- $517.26
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- MDGL - MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share is tracked under CUSIP 558868105.
- 373 institutions reported positions in Q1 2026.
- 4 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 384 to 373 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $13,715,171,776 to $12,441,414,030.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 373 institutions filings for Q1 2026.
Security key
558868105
Latest holder period
Q1 2026
13F holders
373
13D/G owners
4
CIK / CUSIP context first
Open Q1 2026 holders
MDGL full holder history
MADRIGAL PHARMACEUTICALS, INC. SEC filings
MADRIGAL PHARMACEUTICALS, INC. company facts
MADRIGAL PHARMACEUTICALS, INC. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 558868105:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
4
Security
MDGL
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 8.8% | +26% | $1,077,715,260 | +$231,599,280 | 2,018,647 | +27% | JANUS HENDERSON GROUP PLC | 31 Mar 2026 |
| FRIEDMAN PAUL A | 7.8% | $982,730,986 | 1,814,831 | Paul A Friedman, M.D. | 10 Dec 2025 | |||
| Taub Rebecca | 7.8% | $982,730,986 | 1,814,831 | Rebecca Taub, M.D. | 10 Dec 2025 | |||
| PAULSON & CO. INC. | 6.1% | -18% | $743,261,329 | -$168,350,516 | 1,392,188 | -18% | PAULSON & CO. INC. | 31 Mar 2026 |
As of 31 Mar 2026, 373 institutional investors reported holding 23,773,052 shares of MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share (MDGL). This represents 104% of the company’s total 22,822,754 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
81%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 9.4% | 2,141,701 | 0% | 6.4% | $1,121,116,222 |
| JANUS HENDERSON GROUP PLC | 8.8% | 2,018,647 | +27% | 0.5% | $1,051,727,476 |
| RTW INVESTMENTS, LP | 8.7% | 1,993,687 | 0% | 10% | $1,043,635,334 |
| Avoro Capital Advisors LLC | 8% | 1,818,181 | +0.59% | 9.4% | $951,763,208 |
| BlackRock, Inc. | 6.8% | 1,559,965 | -5.2% | 0.01% | $816,594,622 |
| PAULSON & CO. INC. | 6.1% | 1,392,188 | -18% | 23% | $728,768,652 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 3.7% | 841,145 | 0% | 0.02% | $440,314,173 |
| VANGUARD CAPITAL MANAGEMENT LLC | 3.6% | 827,144 | 0% | 0.01% | $432,985,070 |
| WELLINGTON MANAGEMENT GROUP LLP | 3% | 694,958 | +51% | 0.07% | $363,789,664 |
| STATE STREET CORP | 2.7% | 609,525 | +4.5% | 0.01% | $319,068,052 |
| FMR LLC | 2.2% | 511,728 | +16% | 0.01% | $267,873,994 |
| GEODE CAPITAL MANAGEMENT, LLC | 2% | 455,870 | +0.91% | 0.01% | $238,681,931 |
| CITADEL ADVISORS LLC | 2% | 453,843 | +1156% | 0.17% | $237,573,195 |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1.5% | 340,519 | -3.9% | 0.59% | $178,251,481 |
| Invesco Ltd. | 1.4% | 329,519 | -9.8% | 0.03% | $172,493,311 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.4% | 328,110 | +4.6% | 0.02% | $171,757,000 |
| Polar Capital Holdings Plc | 1.3% | 289,310 | +7.1% | 0.66% | $151,445,106 |
| GOLDMAN SACHS GROUP INC | 1.2% | 277,371 | -9.3% | 0.02% | $145,195,396 |
| ARMISTICE CAPITAL, LLC | 1.2% | 264,583 | -0.42% | 4.6% | $138,501,263 |
| Hood River Capital Management LLC | 1.1% | 249,511 | +0.79% | 1.3% | $130,611,523 |
| LORD, ABBETT & CO. LLC | 1.1% | 242,726 | -0.85% | 0.42% | $127,060,000 |
| Point72 Asset Management, L.P. | 0.99% | 225,510 | +78% | 0.21% | $118,047,720 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.95% | 216,720 | -1.1% | 0.02% | $113,446,418 |
| MORGAN STANLEY | 0.84% | 191,294 | +27% | 0.01% | $100,137,080 |
| BANK OF AMERICA CORP /DE/ | 0.83% | 189,527 | -54% | 0.01% | $99,211,699 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
40
Latest
Q1 2026
Rows shown
1-25 of 40
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 23,773,052 | $12,441,414,030 | +$74,301,029 | $523.47 | 373 |
| 2025 Q4 | 23,560,988 | $13,715,171,776 | +$154,180,477 | $582.34 | 384 |
| 2025 Q3 | 23,389,191 | $10,723,496,299 | -$21,867,277 | $458.66 | 352 |
| 2025 Q2 | 23,552,943 | $7,127,866,991 | -$58,976,553 | $302.64 | 303 |
| 2025 Q1 | 23,618,790 | $7,815,274,189 | +$242,480,129 | $331.23 | 317 |
| 2024 Q4 | 22,954,039 | $7,083,805,672 | +$127,209,746 | $308.57 | 282 |
| 2024 Q3 | 22,638,348 | $4,763,047,302 | -$106,585,037 | $212.22 | 252 |
| 2024 Q2 | 22,870,011 | $6,408,116,328 | +$504,945,812 | $280.16 | 255 |
| 2024 Q1 | 21,107,869 | $5,634,735,243 | +$377,318,349 | $267.04 | 263 |
| 2023 Q4 | 19,769,303 | $4,574,587,850 | +$602,581,939 | $231.38 | 225 |
| 2023 Q3 | 17,386,191 | $2,539,343,386 | +$349,378,221 | $146.04 | 206 |
| 2023 Q2 | 14,848,153 | $3,429,412,203 | +$220,213,706 | $231.00 | 208 |
| 2023 Q1 | 13,867,567 | $3,359,361,973 | +$106,522,160 | $242.26 | 221 |
| 2022 Q4 | 13,305,897 | $3,862,135,682 | +$567,009,121 | $290.25 | 186 |
| 2022 Q3 | 11,751,595 | $763,791,382 | -$25,263,206 | $64.99 | 133 |
| 2022 Q2 | 12,001,137 | $857,568,681 | -$17,315,431 | $71.58 | 130 |
| 2022 Q1 | 12,025,725 | $1,179,864,073 | +$26,264,521 | $98.12 | 132 |
| 2021 Q4 | 11,953,948 | $1,012,214,597 | +$40,893,478 | $84.74 | 139 |
| 2021 Q3 | 10,962,747 | $874,847,601 | -$34,316,604 | $79.79 | 126 |
| 2021 Q2 | 11,229,236 | $1,093,866,439 | -$99,083,348 | $97.41 | 147 |
| 2021 Q1 | 12,210,439 | $1,427,893,568 | -$10,189,929 | $116.97 | 135 |
| 2020 Q4 | 12,273,522 | $1,364,432,852 | +$68,881,092 | $111.17 | 132 |
| 2020 Q3 | 11,637,870 | $1,381,764,563 | +$46,463,709 | $118.73 | 125 |
| 2020 Q2 | 11,257,505 | $1,274,820,026 | +$4,793,161 | $113.25 | 124 |
| 2020 Q1 | 11,048,035 | $737,557,931 | +$26,608,051 | $66.76 | 106 |