Security Snapshot

MADRIGAL PHARMACEUTICALS, INC. - Common Stock (MDGL) Institutional Ownership

CUSIP: 558868105

13F Institutional Holders and Ownership History from Q2 2016 to Q2 2026

Latest Period

Q2 2026

Institutions Reporting

410

Shares (Excl. Options)

23,569,318

Price

$536.95

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Latest holder snapshot 5 signals
Portfolio coverage rank
0.01%
Share change
-92,189
Value change
-$46,702,193
Number of holders
410
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
23,203,174
SEC-reported price per share
$544.51
Insider filing price
$544.51
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • MDGL - MADRIGAL PHARMACEUTICALS, INC. - Common Stock is tracked under CUSIP 558868105.
  • 410 institutions reported positions in Q2 2026.
  • 5 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 375 to 410 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from $12,441,824,469 to $12,649,496,579.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 410 institutions filings for Q2 2026.

Open SEC evidence

Security key

558868105

Latest holder period

Q2 2026

13F holders

410

13D/G owners

5

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
5
Security
MDGL
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
JANUS HENDERSON GROUP PLC 8.8% +26% $1,077,715,260 +$231,599,280 2,018,647 +27% JANUS HENDERSON GROUP PLC 31 Mar 2026
FRIEDMAN PAUL A 7.8% $982,730,986 1,814,831 Paul A Friedman, M.D. 10 Dec 2025
Taub Rebecca 7.8% $982,730,986 1,814,831 Rebecca Taub, M.D. 10 Dec 2025
PAULSON & CO. INC. 6.1% -18% $743,261,329 -$168,350,516 1,392,188 -18% PAULSON & CO. INC. 31 Mar 2026
BlackRock, Inc. 4.6% $573,111,435 1,067,346 BlackRock, Inc. 30 Jun 2026

As of 30 Jun 2026, 410 institutional investors reported holding 23,569,318 shares of MADRIGAL PHARMACEUTICALS, INC. - Common Stock (MDGL). This represents 102% of the company’s total 23,203,174 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
77%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BAKER BROS. ADVISORS LP 9.2% 2,143,131 +0.07% 5.8% $1,150,754,190
RTW INVESTMENTS, LP 8.6% 1,993,687 0% 9.1% $1,070,510,235
Jupiter Topco LLC 8.3% 1,936,099 0% 0.42% $1,039,649,606
Avoro Capital Advisors LLC 7.9% 1,833,333 +0.83% 8.8% $984,408,154
PAULSON & CO. INC. 5.8% 1,340,020 -3.7% 28% $719,523,739
BlackRock, Inc. 5.2% 1,200,770 -23% 0.01% $644,753,455
VANGUARD CAPITAL MANAGEMENT LLC 3.6% 835,668 +1% 0.01% $448,711,933
WELLINGTON MANAGEMENT GROUP LLP 3.6% 825,714 +19% 0.08% $443,367,132
VANGUARD PORTFOLIO MANAGEMENT LLC 3.4% 781,731 -7.1% 0.02% $419,750,461
STATE STREET CORP 2.3% 527,057 -14% 0.01% $282,995,975
CITADEL ADVISORS LLC 2.2% 507,233 +12% 0.16% $272,358,759
UBS Group AG 1.7% 401,708 +241% 0.03% $215,697,110
GEODE CAPITAL MANAGEMENT, LLC 1.6% 374,880 -18% 0.01% $201,342,418
FMR LLC 1.5% 356,201 -30% 0.01% $191,262,164
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 1.4% 324,123 -4.8% 0.52% $174,037,845
Invesco Ltd. 1.3% 301,435 -8.5% 0.01% $161,855,524
ARMISTICE CAPITAL, LLC 1.2% 288,000 +8.9% 4.3% $154,641,600
LORD, ABBETT & CO. LLC 1.2% 281,500 +16% 0.43% $151,151,000
GOLDMAN SACHS GROUP INC 1.1% 246,280 -11% 0.01% $132,240,046
Polar Capital Holdings Plc 1.1% 244,274 -16% 0.37% $131,162,924
AMERIPRISE FINANCIAL INC 1% 231,205 +135% 0.03% $124,147,079
NORGES BANK 0.92% 213,886 0.01% $114,846,088
Artisan Partners Limited Partnership 0.91% 210,205 +15% 0.18% $112,869,575
Pictet Asset Management Holding SA 0.83% 192,896 +3% 0.1% $103,486,147
JANE STREET GROUP, LLC 0.83% 191,541 +434% 0.07% $102,847,940

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
41
Latest
Q2 2026
Rows shown
1-25 of 41
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 23,569,318 $12,649,496,579 -$46,702,193 $536.95 410
2026 Q1 23,773,837 $12,441,824,469 +$74,624,268 $523.47 375
2025 Q4 23,561,031 $13,715,196,817 +$154,180,477 $582.34 385
2025 Q3 23,389,191 $10,723,496,299 -$21,867,277 $458.66 352
2025 Q2 23,552,943 $7,127,866,991 -$58,976,553 $302.64 303
2025 Q1 23,618,790 $7,815,274,189 +$242,480,129 $331.23 317
2024 Q4 22,954,039 $7,083,805,672 +$127,209,746 $308.57 282
2024 Q3 22,638,348 $4,763,047,302 -$106,585,037 $212.22 252
2024 Q2 22,870,011 $6,408,116,328 +$504,945,812 $280.16 255
2024 Q1 21,107,869 $5,634,735,243 +$377,318,349 $267.04 263
2023 Q4 19,769,303 $4,574,587,850 +$602,581,939 $231.38 225
2023 Q3 17,386,191 $2,539,343,386 +$349,378,221 $146.04 206
2023 Q2 14,848,153 $3,429,412,203 +$220,213,706 $231.00 208
2023 Q1 13,867,567 $3,359,361,973 +$106,522,160 $242.26 221
2022 Q4 13,305,897 $3,862,135,682 +$567,009,121 $290.25 186
2022 Q3 11,751,595 $763,791,382 -$25,263,206 $64.99 133
2022 Q2 12,001,137 $857,568,681 -$17,315,431 $71.58 130
2022 Q1 12,025,725 $1,179,864,073 +$26,264,521 $98.12 132
2021 Q4 11,953,948 $1,012,214,597 +$40,893,478 $84.74 139
2021 Q3 10,962,747 $874,847,601 -$34,316,604 $79.79 126
2021 Q2 11,229,236 $1,093,866,439 -$99,083,348 $97.41 147
2021 Q1 12,210,439 $1,427,893,568 -$10,189,929 $116.97 135
2020 Q4 12,273,522 $1,364,432,852 +$68,881,092 $111.17 132
2020 Q3 11,637,870 $1,381,764,563 +$46,463,709 $118.73 125
2020 Q2 11,257,505 $1,274,820,026 +$4,793,161 $113.25 124
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