Security key
558868105
MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share (MDGL)
CUSIP: 558868105
Q4 2025 13F Holders as of 31 Dec 2025
- Type / Class
- Equity / Common Stock, $0.0001 par value per share
- Shares outstanding
- 22,822,754
- Total 13F shares
- 23,560,988
- Share change
- +198,837
- Total reported value
- $13,715,171,776
- Put/Call ratio
- 84%
- Price per share
- $582.34
- Number of holders
- 384
- Value change
- +$154,180,477
- Number of buys
- 207
- Number of sells
- 155
Report period
Q4 2025
Institutions
384
Top holders
10
MDGL full security history
Newer quarter: Q1 2026
Previous quarter: Q3 2025
MADRIGAL PHARMACEUTICALS, INC. SEC filings
MADRIGAL PHARMACEUTICALS, INC. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 558868105
Recent filing periods:
Top shareholders of MDGL - MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Paul A. Friedman |
13D/G
|
Paul A Friedman, M.D. |
7.8%
|
1,814,831
|
$982,730,986 | $0 | 10 Dec 2025 | |
| Rebecca Taub |
13D/G
|
Rebecca Taub, M.D. |
7.8%
|
1,814,831
|
$982,730,986 | $0 | 10 Dec 2025 | |
| Kenneth Bate |
3/4/5
|
Director |
0.01%
|
2,627
|
$1,289,808 | -$11,679,363 | 05 Nov 2025 | |
| BAKER BROS. ADVISORS LP |
13F
3/4/5
|
Company · Director |
9.4%
|
2,141,701
|
$982,312,581 | — | 30 Sep 2025 | |
| RTW INVESTMENTS, LP |
13F
|
Company |
8.7%
|
1,993,687
|
$914,424,479 | — | 30 Sep 2025 | |
| PAULSON & CO. INC. |
13F
|
Company |
8.4%
|
1,907,523
|
$874,904,499 | — | 30 Sep 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
8.1%
|
1,842,690
|
$845,277,273 | — | 30 Sep 2025 | |
| Avoro Capital Advisors LLC |
13F
|
Company |
8%
|
1,833,000
|
$840,723,780 | — | 30 Sep 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
7.9%
|
1,812,054
|
$831,116,688 | — | 30 Sep 2025 | |
| BlackRock, Inc. |
13F
|
Company |
6.8%
|
1,559,712
|
$715,377,705 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
2.9%
|
658,097
|
$301,842,770 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
2%
|
446,233
|
$204,700,716 | — | 30 Sep 2025 | |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
1.8%
|
411,802
|
$188,877,105 | — | 30 Sep 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
1.8%
|
404,455
|
$185,507,331 | — | 30 Sep 2025 | |
| FMR LLC |
13F
|
Company |
1.8%
|
401,136
|
$183,985,076 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
1.7%
|
386,100
|
$177,088,626 | — | 30 Sep 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
1.5%
|
352,520
|
$161,688,000 | — | 30 Sep 2025 | |
| Invesco Ltd. |
13F
|
Company |
1.3%
|
299,565
|
$137,398,483 | — | 30 Sep 2025 | |
| Polar Capital Holdings Plc |
13F
|
Company |
1.2%
|
265,154
|
$121,615,534 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
1.1%
|
249,647
|
$114,503,407 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
1.1%
|
244,292
|
$112,046,969 | — | 30 Sep 2025 | |
| Hood River Capital Management LLC |
13F
|
Company |
1.1%
|
242,808
|
$111,366,317 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
0.95%
|
217,343
|
$99,686,540 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.94%
|
213,652
|
$97,993,626 | — | 30 Sep 2025 | |
| Artisan Partners Limited Partnership |
13F
|
Company |
0.9%
|
206,254
|
$94,600,460 | — | 30 Sep 2025 | |
| Erste Asset Management GmbH |
13F
|
Company |
0.88%
|
201,100
|
$89,107,410 | — | 30 Sep 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.84%
|
191,796
|
$87,710,002 | — | 30 Sep 2025 | |
| AMERICAN CENTURY COMPANIES INC |
13F
|
Company |
0.73%
|
165,615
|
$75,961,972 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.7%
|
159,988
|
$73,380,097 | — | 30 Sep 2025 | |
| Rock Springs Capital Management LP |
13F
|
Company |
0.6%
|
137,746
|
$63,178,580 | — | 30 Sep 2025 | |
| Fiera Capital Corp |
13F
|
Company |
0.56%
|
127,800
|
$58,616,748 | — | 30 Sep 2025 | |
| ArrowMark Colorado Holdings LLC |
13F
|
Company |
0.54%
|
123,259
|
$56,533,973 | — | 30 Sep 2025 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
0.53%
|
120,682
|
$55,352,006 | — | 30 Sep 2025 | |
| ALKEON CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.53%
|
120,000
|
$55,039,200 | — | 30 Sep 2025 | |
| ARMISTICE CAPITAL, LLC |
13F
|
Company |
0.53%
|
119,982
|
$55,030,944 | — | 30 Sep 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.51%
|
115,974
|
$53,192,635 | — | 30 Sep 2025 | |
| Affinity Asset Advisors, LLC |
13F
|
Company |
0.5%
|
115,000
|
$52,745,900 | — | 30 Sep 2025 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.46%
|
104,818
|
$48,075,824 | — | 30 Sep 2025 | |
| Woodline Partners LP |
13F
|
Company |
0.46%
|
103,847
|
$47,630,465 | — | 30 Sep 2025 | |
| LORD, ABBETT & CO. LLC |
13F
|
Company |
0.45%
|
102,143
|
$46,849,000 | — | 30 Sep 2025 | |
| MPM BioImpact LLC |
13F
|
Company |
0.44%
|
100,415
|
$46,056,344 | — | 30 Sep 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.43%
|
97,779
|
$44,847,395 | — | 30 Sep 2025 | |
| D. E. Shaw & Co., Inc. |
13F
|
Company |
0.42%
|
96,182
|
$44,114,836 | — | 30 Sep 2025 | |
| JANE STREET GROUP, LLC |
13F
|
Company |
0.42%
|
95,734
|
$43,909,357 | — | 30 Sep 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
0.39%
|
88,500
|
$40,591,410 | — | 30 Sep 2025 | |
| Connor, Clark & Lunn Investment Management Ltd. |
13F
|
Company |
0.38%
|
85,773
|
$39,340,644 | — | 30 Sep 2025 | |
| BALYASNY ASSET MANAGEMENT L.P. |
13F
|
Company |
0.36%
|
82,401
|
$37,794,043 | — | 30 Sep 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.33%
|
75,570
|
$34,660,936 | — | 30 Sep 2025 | |
| EcoR1 Capital, LLC |
13F
|
Company |
0.33%
|
75,000
|
$34,399,500 | — | 30 Sep 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.32%
|
73,715
|
$33,810,122 | — | 30 Sep 2025 |
Institutional Holders of MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share (MDGL) as of Q4 2025
As of 31 Dec 2025,
MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share (MDGL) was held by
384 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
23,560,988 shares.
The largest 10 holders included
BAKER BROS. ADVISORS LP, RTW INVESTMENTS, LP, VANGUARD GROUP INC, Avoro Capital Advisors LLC, PAULSON & CO. INC., BlackRock, Inc., JANUS HENDERSON GROUP PLC, STATE STREET CORP, WELLINGTON MANAGEMENT GROUP LLP, and GEODE CAPITAL MANAGEMENT, LLC.
This page lists
384
institutional shareholders reporting positions in this security
for the Q4 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
352
Q4 2025 holders
384
Holder diff
32
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.