MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share (MDGL)

Q: What does CUSIP 558868105 represent in this 13F holders report?

CUSIP 558868105 is the security identifier for MDGL - MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share used to aggregate holder disclosures.

Q: How many institutions held MDGL - MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share in Q4 2021?

139 institutional investors reported MDGL - MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share for Q4 2021. Use the holders table for investor-level position and value details.

CUSIP: 558868105

Q4 2021 13F Holders as of 31 Dec 2021

Security type / class: Equity / Common Stock, $0.0001 par value per share
Total 13F shares: 11,953,948
Total 13F value: $1,012,214,597
Share change: +473,210
Put/Call ratio: 99%
SEC-reported price per share: $84.74
Number of holders: 139
Value change: +$40,893,478
Number of buys: 61
Number of sells: 51
Shares outstanding: 22,822,754

Security key

558868105

Report period

Q4 2021

Institutions

139

Top holders

MDGL full security history Ownership snapshot Full 13F holder table Newer quarter: Q1 2022 Previous quarter: Q3 2021 MADRIGAL PHARMACEUTICALS, INC. SEC filings MADRIGAL PHARMACEUTICALS, INC. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 558868105

Newer quarter: Q1 2022 Previous quarter: Q3 2021

Recent filing periods:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Ownership snapshot

Top reported holders of MDGL - MADRIGAL PHARMACEUTICALS, INC. - Common Stock, $0.0001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

BAKER BROS. ADVISORS LP

Disclosed value leader

BAKER BROS. ADVISORS LP

Comparable rows

15/15

Latest evidence

30 Sep 2021

13F Lead comparable stake: 6.6% Showing 1-6 of 15 holder rows.

Quick read

BAKER BROS. ADVISORS LP leads the comparable SEC ownership view at 6.6%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens BAKER BROS. ADVISORS LP's linked filing trail.

Comparable ownership Top 5

BAKER BROS. ADVISORS LP 6.6%

Avoro Capital Advisors LLC 6.2%

VANGUARD GROUP INC 4.7%

ARMISTICE CAPITAL, LLC 4.5%

WELLINGTON MANAGEMENT GROUP LLP 4.5%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
BAKER BROS. ADVISORS LP	13F Company 13F	6.6%	$119,622,000 1,499,213 shares	—	30 Sep 2021
Avoro Capital Advisors LLC	13F Company 13F	6.2%	$113,701,000 1,425,000 shares	—	30 Sep 2021
VANGUARD GROUP INC	13F Company 13F	4.7%	$85,497,000 1,071,530 shares	—	30 Sep 2021
ARMISTICE CAPITAL, LLC	13F Company 13F	4.5%	$82,662,000 1,036,000 shares	—	30 Sep 2021
WELLINGTON MANAGEMENT GROUP LLP	13F Company 13F	4.5%	$81,228,000 1,018,018 shares	—	30 Sep 2021
BlackRock Finance, Inc.	13F Company 13F	4%	$73,070,000 915,789 shares	—	30 Sep 2021

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2021

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

139

11,953,948

Rows available

139

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2021 vs Q3 2021 Across Filers

Q3 2021 holders

126

Q4 2021 holders

139

Holder diff

Investor	Q3 2021 Shares	Q4 2021 Shares	Share Diff	Share Chg %	Q3 2021 value	Q4 2021 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend