Security Snapshot

Wave Life Sciences Ltd. - Ordinary Shares, no par value (WVE) Institutional Ownership

CUSIP: Y95308105

13F Institutional Holders and Ownership History from Q4 2015 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

226

Shares (Excl. Options)

172,478,533

Price

$7.25

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Latest holder snapshot 5 signals
Portfolio coverage rank
0.01%
Share change
-10,620,214
Value change
-$203,869,620
Number of holders
226
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
188,679,245
SEC-reported price per share
$6.42
Insider filing price
$6.42
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • WVE - Wave Life Sciences Ltd. - Ordinary Shares, no par value is tracked under CUSIP Y95308105.
  • 226 institutions reported positions in Q1 2026.
  • 5 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 218 to 226 between Q4 2025 and Q1 2026.
  • SEC-reported value moved from $3,108,291,748 to $1,247,355,027.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 226 institutions filings for Q1 2026.

Open SEC evidence

Security key

Y95308105

Latest holder period

Q1 2026

13F holders

226

13D/G owners

5

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
5
Security
WVE
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
RA CAPITAL MANAGEMENT, L.P. 17% -2.2% $248,138,341 34,225,506 0% RA Capital Management, L.P. 15 Apr 2026
BlackRock, Inc. 6.1% $63,555,507 9,360,163 BlackRock, Inc. 31 Dec 2024
MAVERICK CAPITAL LTD 5.4% $56,093,833 8,261,242 Maverick Capital, Ltd. 31 Dec 2024
FMR LLC 2.8% -63% $37,284,027 -$70,566,627 5,192,761 -65% FMR LLC 31 Mar 2026
Adage Capital Management, L.P. 0.53% -96% $7,180,000 -$63,083,918 1,000,000 -90% Adage Capital Management, L.P. 31 Mar 2026

As of 31 Mar 2026, 226 institutional investors reported holding 172,478,533 shares of Wave Life Sciences Ltd. - Ordinary Shares, no par value (WVE). This represents 91% of the company’s total 188,679,245 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
72%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
RA CAPITAL MANAGEMENT, L.P. 14% 26,975,505 +48% 2.1% $195,572,411
GSK plc 9.7% 18,245,691 0% 22% $132,281,260
BlackRock, Inc. 7.5% 14,117,412 +12% 0% $102,351,241
MAVERICK CAPITAL LTD 5.4% 10,161,399 +9.5% 0.86% $73,670,143
PRICE T ROWE ASSOCIATES INC /MD/ 4.6% 8,704,550 +18% 0.01% $63,109,000
Driehaus Capital Management LLC 2.9% 5,431,021 -17% 0.29% $39,374,902
FEDERATED HERMES, INC. 2.8% 5,317,457 +12% 0.06% $38,551,563
FMR LLC 2.8% 5,192,761 -66% 0% $37,647,520
683 Capital Management, LLC 2.6% 4,900,000 +22% 3.3% $35,525,000
PRIMECAP MANAGEMENT CO/CA/ 2.6% 4,832,952 +18% 0.03% $35,038,906
M28 Capital Management LP 2.4% 4,588,284 -19% 62% $33,265,059
STATE STREET CORP 1.9% 3,674,033 +23% 0% $26,636,739
GEODE CAPITAL MANAGEMENT, LLC 1.9% 3,579,099 +13% 0% $25,953,676
Siren, L.L.C. 1.3% 2,450,000 0% 0.49% $17,762,500
CITADEL ADVISORS LLC 1.2% 2,202,856 +179% 0.01% $15,970,706
TWO SIGMA INVESTMENTS, LP 1% 1,878,115 +151% 0.01% $13,616,334
Pfizer Inc 0.99% 1,875,000 0% 5% $11,934,375
First Light Asset Management, LLC 0.98% 1,843,968 -0.53% 1.2% $13,368,768
MARSHALL WACE, LLP 0.95% 1,789,882 0.01% $12,976,646
VANGUARD CAPITAL MANAGEMENT LLC 0.85% 1,611,853 0% 0% $11,685,934
Squarepoint Ops LLC 0.78% 1,462,390 +66% 0.02% $10,602,328
SCHRODER INVESTMENT MANAGEMENT GROUP 0.76% 1,441,059 +43% 0.01% $9,539,811
Affinity Asset Advisors, LLC 0.74% 1,401,727 -48% 0.6% $10,162,521
GOLDMAN SACHS GROUP INC 0.73% 1,383,590 -52% 0% $10,031,028
MORGAN STANLEY 0.72% 1,361,001 +232% 0% $9,867,260

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
42
Latest
Q1 2026
Rows shown
1-25 of 42
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 172,478,533 $1,247,355,027 -$203,869,620 $7.25 226
2025 Q4 182,758,755 $3,108,291,748 +$421,681,651 $17.00 218
2025 Q3 143,680,189 $1,051,640,675 +$37,184,597 $7.32 187
2025 Q2 138,939,054 $903,136,388 +$46,387,682 $6.50 174
2025 Q1 131,293,097 $1,061,209,645 +$20,316,471 $8.08 192
2024 Q4 128,616,529 $1,591,015,441 +$86,595,360 $12.37 181
2024 Q3 120,246,621 $986,101,781 +$176,011,863 $8.20 160
2024 Q2 95,071,148 $474,405,111 +$9,854,270 $4.99 143
2024 Q1 92,759,614 $572,308,103 +$4,033,614 $6.17 131
2023 Q4 92,528,153 $468,029,084 +$93,144,169 $5.05 115
2023 Q3 72,598,087 $417,436,128 +$3,006,886 $5.75 85
2023 Q2 72,147,137 $262,614,478 +$6,429,830 $3.64 80
2023 Q1 70,086,593 $303,466,627 +$3,780,454 $4.33 72
2022 Q4 68,108,089 $476,736,473 +$7,420,705 $7.00 74
2022 Q3 67,256,615 $242,816,542 -$1,613,831 $3.61 58
2022 Q2 67,784,074 $220,297,785 +$69,127,143 $3.25 56
2022 Q1 47,551,964 $95,097,268 -$1,035,989 $2.00 77
2021 Q4 47,284,486 $148,479,513 +$13,347,500 $3.14 87
2021 Q3 37,428,616 $183,549,240 +$443,975 $4.90 84
2021 Q2 37,041,603 $246,689,021 -$5,849,970 $6.66 82
2021 Q1 38,281,847 $214,782,368 +$1,495,724 $5.61 97
2020 Q4 36,092,793 $284,070,815 -$9,567,182 $7.87 102
2020 Q3 37,117,728 $315,928,313 +$59,335,508 $8.49 106
2020 Q2 29,422,263 $306,287,769 -$6,711,423 $10.41 89
2020 Q1 30,100,828 $282,072,986 +$9,439,494 $9.37 76
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