RA CAPITAL MANAGEMENT, L.P.

Holdings History for Wave Life Sciences Ltd. - Ordinary Shares, no par value (WVE)

Symbol: WVE on Nasdaq
Investment type: Equity / Ordinary Shares, no par value
Latest Disclosed Shares Owned: 25,453,010 shares
Security Ownership %: 13%

Shares, Excluding Options vs Price

Value, Excluding Options

RA Capital Management, L.P. ownership in Wave Life Sciences Ltd. Ordinary Shares, no par value (WVE)

15 Dec 2025 - RA Capital Management, L.P. has filed an SCHEDULE 13D/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 25,453,010 shares of Wave Life Sciences Ltd. Ordinary Shares, no par value (WVE). This represents 13% ownership of the company. In their previous filing dated 13 Nov 2025, RA CAPITAL MANAGEMENT, L.P. had reported owning 25,453,010 shares, indicating a new holding.

Reporting Name	Ownership %	Change	Value $	Shares owned	Change	Activity %	Price	Form	Report date	Filing time
RA Capital Management, L.P.	13%	-8%	$169,771,577	25,453,010	0		$6.67	13D/A	11 Dec 2025	15 Dec 2025, 17:04
RA Capital Management, L.P.	15%		$186,316,033	25,453,010			$7.32	13D/A	11 Nov 2025	13 Nov 2025, 20:47

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025	3.2%	+0%	$309,451,153	18,203,009	+1,000	+0.01%	$17.00	Q4 2025
30 Sep 2025	1.6%	0%	$133,238,706	18,202,009	0		$7.32	Q3 2025
30 Jun 2025	2%	0%	$118,313,059	18,202,009	0		$6.50	Q2 2025
31 Mar 2025	2.5%	0%	$147,072,233	18,202,009	0		$8.08	Q1 2025
31 Dec 2024	3%	0%	$225,158,851	18,202,009	0		$12.37	Q4 2024
30 Sep 2024	1.7%	0%	$149,256,474	18,202,009	0		$8.20	Q3 2024
30 Jun 2024	1.2%	0%	$90,828,025	18,202,009	0		$4.99	Q2 2024
31 Mar 2024	1.4%	0%	$112,306,396	18,202,009	0		$6.17	Q1 2024
31 Dec 2023	1.4%	+0.08%	$91,920,145	18,202,009	+1,000,000	+5.8%	$5.05	Q4 2023
30 Sep 2023	1.9%	0%	$98,911,552	17,202,009	0		$5.75	Q3 2023
30 Jun 2023	1.2%	0%	$62,615,313	17,202,009	0		$3.64	Q2 2023
31 Mar 2023	1.7%	0%	$74,484,699	17,202,009	0		$4.33	Q1 2023
31 Dec 2022	2.4%	0%	$120,414,063	17,202,009	0		$7.00	Q4 2022
30 Sep 2022	1.3%	0%	$62,099,000	17,202,009	0		$3.61	Q3 2022
30 Jun 2022	1.5%	+0.82%	$55,907,000	17,202,009	+9,426,802	+121%	$3.25	Q2 2022
31 Mar 2022	0.34%	0%	$15,550,000	7,775,207	0		$2.00	Q1 2022
31 Dec 2021	0.43%	0%	$24,414,000	7,775,207	0		$3.14	Q4 2021
30 Sep 2021	0.53%	0%	$38,099,000	7,775,207	0		$4.90	Q3 2021
30 Jun 2021	0.84%	0%	$51,783,000	7,775,207	0		$6.66	Q2 2021
31 Mar 2021	0.66%	0%	$43,619,000	7,775,207	0		$5.61	Q1 2021
31 Dec 2020	0.86%	0%	$61,191,000	7,775,207	0		$7.87	Q4 2020
30 Sep 2020	1.2%	0%	$66,012,000	7,775,207	0		$8.49	Q3 2020
30 Jun 2020	1.6%	0%	$80,940,000	7,775,207	0		$10.41	Q2 2020
31 Mar 2020	2.3%	0%	$72,854,000	7,775,207	0		$9.37	Q1 2020
31 Dec 2019	1.9%	0%	$62,318,000	7,775,207	0		$8.01	Q4 2019
30 Sep 2019	9.5%	0%	$159,625,000	7,775,207	0		$20.53	Q3 2019
30 Jun 2019	12%	0%	$202,855,000	7,775,207	0		$26.09	Q2 2019
31 Mar 2019	14%	+0.46%	$302,067,000	7,775,207	+263,158	+3.5%	$38.85	Q1 2019
31 Dec 2018	19%	0%	$315,807,000	7,512,049	0		$42.04	Q4 2018
30 Sep 2018	20%	0%	$375,602,000	7,512,049	0		$50.00	Q3 2018
30 Jun 2018	19%	0%	$287,336,000	7,512,049	0		$38.25	Q2 2018
31 Mar 2018	23%	0%	$301,233,000	7,512,049	0		$40.10	Q1 2018
31 Dec 2017	22%	+1.2%	$263,673,000	7,512,049	+423,398	+6%	$35.10	Q4 2017
30 Sep 2017	15%	0%	$154,178,000	7,088,651	0		$21.75	Q3 2017
30 Jun 2017	15%	0%	$131,849,000	7,088,651	0		$18.60	Q2 2017
31 Mar 2017	24%	0%	$194,938,000	7,088,651	0		$27.50	Q1 2017
31 Dec 2016	26%	0%	$185,368,000	7,088,651	0		$26.15	Q4 2016
30 Sep 2016	24%	0%	$230,168,000	7,088,651	0		$32.47	Q3 2016
30 Jun 2016	20%	0%	$146,664,000	7,088,651	0		$20.69	Q2 2016
31 Mar 2016	13%	0%	$98,390,000	7,088,651	0		$13.88	Q1 2016
31 Dec 2015	11%	+11%	$113,064,000	7,088,651	+7,088,651	NEW	$15.95	Q4 2015

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.