Quick Takeaways
- WVE - Wave Life Sciences Ltd. has 19 insiders with reported activity on this page.
- Net insider value flow over the last year: +$227,552,420.
- Recent transaction rows are available for direct filing-level review.
Issuer insider activity is sourced from SEC Forms 3, 4, and 5.
Net insider flow leans to buying over the last 12 months. Net value: +$227,552,420.
$246,434,199
Shares: 36,560,984
Insiders: 5
$18,881,780
Shares: 1,392,728
Insiders: 11
+$227,552,420
Shares: +35,168,256
Insiders: -6
| Window (months) | Buy shares | Sell shares | Buy $ | Sell $ | Net $ |
|---|---|---|---|---|---|
| 0-3 | 35,089,984 | 33,194 | $218,497,512 | $499,593 | +$217,997,919 |
| 3-6 | 1,471,000 | 1,065,514 | $27,936,688 | $15,546,943 | +$12,389,745 |
| 6-9 | 0 | 258,021 | $0 | $2,574,253 | -$2,574,253 |
| 9-12 | 0 | 35,999 | $0 | $260,991 | -$260,991 |
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| GSK plc | 10%+ Owner | $346,668,129 | +$27,930,000 | +8.8% | Filing P/S | 11 Dec 2025 |
| RA Capital Healthcare Fund LP | Director, 10%+ Owner | $175,340,782 | +$54,624,378 | +45% | Filing P/S | 26 Mar 2026 |
| Peter Kolchinsky | Director, 10%+ Owner | $175,340,782 | +$54,624,378 | +45% | Filing P/S | 26 Mar 2026 |
| RA CAPITAL MANAGEMENT, L.P. | Director, 10%+ Owner | $175,340,782 | +$54,631,065 | +45% | Filing P/S | 26 Mar 2026 |
| Rajeev M. Shah | Director, 10%+ Owner | $175,340,782 | +$54,624,378 | +45% | Filing P/S | 26 Mar 2026 |
| Ken Takanashi | Director | $163,715,967 | -$42,630 | -0.03% | Mixed | 23 Mar 2026 |
| Chandra Vargeese | Chief Technology Officer, Head of Platform Discovery Sciences | $5,490,908 | -$43,417 | -0.78% | Filing P/S | 05 Feb 2026 |
| Gregory L. Verdine | Director | $3,866,798 | -$577,961 | -13% | Filing P/S | 08 Dec 2025 |
| Paul Bolno | President and CEO, Director | $3,705,744 | -$2,335,766 | -39% | Filing P/S | 05 Feb 2026 |
| Kyle Moran | Chief Financial Officer | $1,807,478 | -$4,152,238 | -70% | Filing P/S | 05 Feb 2026 |
| Chris Francis | SVP, Corporate Development, Head of Emerging Areas | $928,005 | -$7,102,264 | -88% | Filing P/S | 26 Feb 2026 |
| Erik Ingelsson | Chief Scientific Officer | $637,022 | Median | 09 Apr 2026 | ||
| Heidi L. Wagner | Director | $629,020 | -$189,000 | -23% | Filing P/S | 08 Dec 2025 |
| Mark Corrigan | Director | $405,282 | -$217,297 | -35% | Filing P/S | 08 Dec 2025 |
| Christopher I. Wright | Chief Medical Officer | $330,785 | Median | 09 Apr 2026 | ||
| Aik Na Tan | Director | $323,850 | -$2,027,270 | -86% | Filing P/S | 08 Dec 2025 |
| Henry Christian O | Director | $228,854 | -$1,454,516 | -86% | Filing P/S | 08 Dec 2025 |
| Adrian Rawcliffe | Director | $190,500 | -$739,421 | -80% | Filing P/S | 08 Dec 2025 |
| Michael A. Panzara | Chief Medical Officer, Head of Therapeutics Discovery and Development | Mixed | 25 Jul 2022 |
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| GSK plc |
3/4/5
13F
|
10%+ Owner · Company |
9.8%
|
18,245,691
|
$346,668,129 | +$27,930,000 | 11 Dec 2025 | |
| RA CAPITAL MANAGEMENT, L.P. |
13F
13D/G
3/4/5
|
Company · Director, 10%+ Owner |
17%
from 13D/G
|
18,203,009
|
$309,451,153 | — | 31 Dec 2025 | |
| FMR LLC |
13F
13D/G
|
Company |
2.8%
from 13D/G
|
15,135,983
|
$257,311,705 | — | 31 Dec 2025 | |
| BlackRock, Inc. |
13F
13D/G
|
Company |
6.1%
from 13D/G
|
12,648,907
|
$215,031,419 | — | 31 Dec 2025 | |
| Peter Kolchinsky |
3/4/5
|
Director, 10%+ Owner |
15%
|
26,975,505
|
$175,340,782 | +$54,624,378 | 26 Mar 2026 | |
| RA Capital Healthcare Fund LP |
3/4/5
|
Director, 10%+ Owner |
15%
|
26,975,505
|
$175,340,782 | +$54,624,378 | 26 Mar 2026 | |
| Rajeev M. Shah |
3/4/5
|
Director, 10%+ Owner |
15%
|
26,975,505
|
$175,340,782 | +$54,624,378 | 26 Mar 2026 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
5.3%
|
9,786,061
|
$166,363,037 | — | 31 Dec 2025 | |
| Ken Takanashi |
3/4/5
|
Director |
—
mixed-class rows
|
9,706,551
mixed-class rows
|
$163,715,967 | -$42,630 | 23 Mar 2026 | |
| MAVERICK CAPITAL LTD |
13F
13D/G
|
Company |
5.4%
from 13D/G
|
9,280,237
|
$157,764,029 | — | 31 Dec 2025 | |
| Adage Capital Management, L.P. |
13D/G
|
— |
5.4%
|
9,786,061
|
$139,157,787 | -$74,376,843 | 31 Dec 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
4%
|
7,407,372
|
$125,927,000 | — | 31 Dec 2025 | |
| Darwin Global Management, Ltd. |
13F
|
Company |
3.9%
|
7,298,421
|
$125,167,920 | — | 31 Dec 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
3.5%
|
6,581,067
|
$111,878,139 | — | 31 Dec 2025 | |
| M28 Capital Management LP |
13F
|
Company |
3.1%
|
5,664,548
|
$96,297,316 | — | 31 Dec 2025 | |
| FEDERATED HERMES, INC. |
13F
|
Company |
2.6%
|
4,744,520
|
$80,656,840 | — | 31 Dec 2025 | |
| PRIMECAP MANAGEMENT CO/CA/ |
13F
|
Company |
2.2%
|
4,095,282
|
$69,619,794 | — | 31 Dec 2025 | |
| 683 Capital Management, LLC |
13F
|
Company |
2.2%
|
4,015,000
|
$68,255,000 | — | 31 Dec 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
1.9%
|
3,573,746
|
$60,753,682 | — | 31 Dec 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.7%
|
3,170,110
|
$53,902,133 | — | 31 Dec 2025 | |
| STATE STREET CORP |
13F
|
Company |
1.6%
|
2,996,084
|
$50,933,428 | — | 31 Dec 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
1.5%
|
2,854,082
|
$48,519,394 | — | 31 Dec 2025 | |
| Affinity Asset Advisors, LLC |
13F
|
Company |
1.5%
|
2,700,000
|
$45,900,000 | — | 31 Dec 2025 | |
| EMERALD ADVISERS, LLC |
13F
|
Company |
1.3%
|
2,455,089
|
$41,736,513 | — | 31 Dec 2025 | |
| Siren, L.L.C. |
13F
|
Individual |
1.3%
|
2,450,000
|
$41,650,000 | — | 31 Dec 2025 | |
| Kynam Capital Management, LP |
13F
|
Company |
1.2%
|
2,169,105
|
$36,874,785 | — | 31 Dec 2025 | |
| LOOMIS SAYLES & CO L P |
13F
|
Company |
1.1%
|
2,040,223
|
$34,683,791 | — | 31 Dec 2025 | |
| PFIZER INC |
13F
|
Company |
1%
|
1,875,000
|
$31,875,000 | — | 31 Dec 2025 | |
| First Light Asset Management, LLC |
13F
|
Company |
1%
|
1,853,851
|
$31,515,467 | — | 31 Dec 2025 | |
| Bellevue Group AG |
13F
|
Company |
0.8%
|
1,490,518
|
$25,338,806 | — | 31 Dec 2025 | |
| EMERALD MUTUAL FUND ADVISERS TRUST |
13F
|
Company |
0.76%
|
1,414,665
|
$24,049,305 | — | 31 Dec 2025 | |
| RTW INVESTMENTS, LP |
13F
|
Company |
0.73%
|
1,350,000
|
$22,950,000 | — | 31 Dec 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.64%
|
1,191,361
|
$20,253,137 | — | 31 Dec 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.56%
|
1,033,068
|
$17,562,156 | — | 31 Dec 2025 | |
| SCHRODER INVESTMENT MANAGEMENT GROUP |
13F
|
Company |
0.54%
|
1,005,984
|
$17,252,626 | — | 31 Dec 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.48%
|
892,886
|
$15,179,062 | — | 31 Dec 2025 | |
| Squarepoint Ops LLC |
13F
|
Company |
0.48%
|
883,586
|
$15,020,962 | — | 31 Dec 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.43%
|
805,901
|
$13,829,854 | — | 31 Dec 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.43%
|
789,964
|
$13,429,388 | — | 31 Dec 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
0.4%
|
749,448
|
$12,740,616 | — | 31 Dec 2025 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.39%
|
722,237
|
$12,278,029 | — | 31 Dec 2025 | |
| TANG CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.32%
|
600,000
|
$10,200,000 | — | 31 Dec 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.32%
|
584,633
|
$9,938,761 | — | 31 Dec 2025 | |
| EVENTIDE ASSET MANAGEMENT, LLC |
13F
|
Company |
0.27%
|
500,000
|
$8,500,000 | — | 31 Dec 2025 | |
| KENNEDY CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.27%
|
492,437
|
$8,371,429 | — | 31 Dec 2025 | |
| Elmind Capital, LP |
13F
|
Company |
0.24%
|
447,846
|
$7,613,382 | — | 31 Dec 2025 | |
| Exome Asset Management LLC |
13F
|
Company |
0.23%
|
421,488
|
$7,165,296 | — | 31 Dec 2025 | |
| Universal- Beteiligungs- und Servicegesellschaft mbH |
13F
|
Individual |
0.22%
|
411,494
|
$6,995,398 | — | 31 Dec 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.22%
|
409,663
|
$6,964,277 | — | 31 Dec 2025 | |
| SPHERA FUNDS MANAGEMENT LTD. |
13F
|
Company |
0.22%
|
408,166
|
$6,938,822 | — | 31 Dec 2025 |
Showing up to 300 most recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | Value $ | * Price $ | Shares | Shares Owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 3.73% | $6,312,092 | $6.50 | 971,091 | 26,975,505 | 30 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 3.73% | $6,312,092 | $6.50 | 971,091 | 26,975,505 | 30 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 3.73% | $6,312,092 | $6.50 | 971,091 | 26,975,505 | 30 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 3.73% | $6,312,092 | $6.50 | 971,091 | 26,975,505 | 30 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 10.6% | $16,046,856 | $6.43 | 2,495,623 | 26,004,414 | 27 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 10.6% | $16,046,856 | $6.43 | 2,495,623 | 26,004,414 | 27 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 10.6% | $16,046,856 | $6.43 | 2,495,623 | 26,004,414 | 27 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 10.6% | $16,046,856 | $6.43 | 2,495,623 | 26,004,414 | 27 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 29.2% | $32,265,431 | $6.08 | 5,305,782 | 23,508,791 | 26 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 29.2% | $32,265,431 | $6.08 | 5,305,782 | 23,508,791 | 26 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 29.2% | $32,265,431 | $6.08 | 5,305,782 | 23,508,791 | 26 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 29.2% | $32,265,431 | $6.08 | 5,305,782 | 23,508,791 | 26 Mar 2026 | See footnotes |
| Ken Takanashi | WVE | Ordinary Shares | Conversion of derivative security | 68.4% | 3,901,348 | 9,606,408 | 23 Mar 2026 | See Footnote | ||
| Ken Takanashi | WVE | Series A Preferred Shares | Conversion of derivative security | -100% | -3,901,348 | 0 | 23 Mar 2026 | See Footnote | ||
| Chris Francis | WVE | Ordinary Shares | Sale | -34.9% | $499,593 | $15.05 | -33,194 | 61,867 | 26 Feb 2026 | Direct |
| Chris Francis | WVE | Ordinary Shares | Options Exercise | 71.3% | 33,194 | 79,767 | 26 Feb 2026 | Direct | ||
| Chris Francis | WVE | Share Option (right to buy) | Options Exercise | -35.2% | -33,194 | 61,175 | 26 Feb 2026 | Direct | ||
| Kyle Moran | WVE | Ordinary Shares | Sale | -2.6% | $48,259 | $13.45 | -3,588 | 134,385 | 09 Feb 2026 | Direct |
| Paul Bolno | WVE | Ordinary Shares | Sale | -3.66% | $140,956 | $13.45 | -10,480 | 275,520 | 09 Feb 2026 | Direct |
| Chris Francis | WVE | Ordinary Shares | Sale | -2.95% | $25,326 | $13.45 | -1,883 | 61,867 | 09 Feb 2026 | Direct |
| Chandra Vargeese | WVE | Ordinary Shares | Sale | -0.78% | $43,417 | $13.45 | -3,228 | 408,246 | 09 Feb 2026 | Direct |
| Kyle Moran | WVE | Ordinary Shares | Award | 49.4% | 45,625 | 137,973 | 05 Feb 2026 | Direct | ||
| Kyle Moran | WVE | Share Option (right to buy) | Award | 273,750 | 273,750 | 05 Feb 2026 | Direct | |||
| Paul Bolno | WVE | Ordinary Shares | Award | 136.4% | 165,000 | 286,000 | 05 Feb 2026 | Direct | ||
| Paul Bolno | WVE | Share Option (right to buy) | Award | 1,000,000 | 1,000,000 | 05 Feb 2026 | Direct | |||
| Chris Francis | WVE | Ordinary Shares | Award | 155% | 38,750 | 63,750 | 05 Feb 2026 | Direct | ||
| Chris Francis | WVE | Share Option (right to buy) | Award | 232,500 | 232,500 | 05 Feb 2026 | Direct | |||
| Chandra Vargeese | WVE | Ordinary Shares | Award | 12.5% | 45,625 | 411,474 | 05 Feb 2026 | Direct | ||
| Chandra Vargeese | WVE | Share Option (right to buy) | Award | 273,750 | 273,750 | 05 Feb 2026 | Direct | |||
| Chris Francis | WVE | Ordinary Shares | Sale | -27.3% | $150,260 | $16.03 | -9,375 | 25,000 | 02 Jan 2026 | Direct |
| Chris Francis | WVE | Ordinary Shares | Options Exercise | 37.5% | 9,375 | 34,375 | 02 Jan 2026 | Direct | ||
| Chris Francis | WVE | Share Option (right to buy) | Options Exercise | -100% | -9,375 | 0 | 02 Jan 2026 | Direct | ||
| GSK plc | WVE | Ordinary Shares | Purchase | 8.76% | $27,930,000 | $19.00 | 1,470,000 | 18,245,691 | 11 Dec 2025 | By Corporation |
| Kyle Moran | WVE | Ordinary Shares | Sale | -35.9% | $1,001,979 | $20.03 | -50,036 | 89,218 | 09 Dec 2025 | Direct |
| Kyle Moran | WVE | Ordinary Shares | Options Exercise | 161.6% | 86,000 | 139,218 | 09 Dec 2025 | Direct | ||
| Kyle Moran | WVE | Share Option (right to buy) | Award | -100% | -86,000 | 0 | 09 Dec 2025 | Direct | ||
| Heidi L. Wagner | WVE | Ordinary Shares | Sale | -23.8% | $189,000 | $13.50 | -14,000 | 44,930 | 08 Dec 2025 | Direct |
| Heidi L. Wagner | WVE | Ordinary Shares | Options Exercise | 36.9% | 14,000 | 51,930 | 08 Dec 2025 | Direct | ||
| Heidi L. Wagner | WVE | Share Option (right to buy) | Options Exercise | -66.7% | -14,000 | 7,000 | 08 Dec 2025 | Direct | ||
| Aik Na Tan | WVE | Ordinary Shares | Options Exercise | 119,230 | 70,400 | 08 Dec 2025 | Direct | |||
| Aik Na Tan | WVE | Ordinary Shares | Sale | -84.1% | $1,823,158 | $13.58 | -134,218 | 25,400 | 08 Dec 2025 | Direct |
| Aik Na Tan | WVE | Share Option (right to buy) | Options Exercise | -100% | -119,230 | 0 | 08 Dec 2025 | Direct | ||
| Chris Francis | WVE | Ordinary Shares | Sale | -94.6% | $6,427,085 | $14.57 | -441,031 | 25,000 | 08 Dec 2025 | Direct |
| Chris Francis | WVE | Ordinary Shares | Options Exercise | 441,031 | 147,349 | 08 Dec 2025 | Direct | |||
| Chris Francis | WVE | Share Option (right to buy) | Options Exercise | -100% | -441,031 | 0 | 08 Dec 2025 | Direct | ||
| Kyle Moran | WVE | Ordinary Shares | Sale | -70.2% | $3,102,000 | $14.77 | -210,000 | 89,218 | 08 Dec 2025 | Direct |
| Kyle Moran | WVE | Ordinary Shares | Options Exercise | 210,000 | 189,218 | 08 Dec 2025 | Direct | |||
| Kyle Moran | WVE | Share Option (right to buy) | Award | -100% | -210,000 | 0 | 08 Dec 2025 | Direct | ||
| Gregory L. Verdine | WVE | Ordinary Shares | Sale | -6.77% | $269,461 | $13.47 | -20,000 | 275,217 | 08 Dec 2025 | Direct |
| Adrian Rawcliffe | WVE | Ordinary Shares | Sale | -76.8% | $630,000 | $15.00 | -42,000 | 12,700 | 08 Dec 2025 | Direct |