Comparable stake leader
RA CAPITAL MANAGEMENT, L.P.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001631574.
Comparable stake leader
RA CAPITAL MANAGEMENT, L.P.
Disclosed value leader
GSK plc
Comparable rows
50/50
Latest evidence
15 Apr 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. |
13D/G
3/4/5
13F
Director, 10%+ Owner · Company
|
17%
|
$248,138,341
34,225,506 shares
|
$0 | 15 Apr 2026 |
| BlackRock, Inc. |
13F
13D/G
Company
|
6.1%
from 13D/G
|
$102,351,241
14,117,412 shares
|
— | 31 Mar 2026 |
| MAVERICK CAPITAL LTD |
13F
13D/G
Company
|
5.4%
from 13D/G
|
$73,670,143
10,161,399 shares
|
— | 31 Mar 2026 |
| FMR LLC |
13F
13D/G
Company
|
2.8%
from 13D/G
|
$37,647,520
5,192,761 shares
|
— | 31 Mar 2026 |
| Adage Capital Management, L.P. |
13D/G
|
0.53%
|
$7,180,000
1,000,000 shares
|
-$63,083,918 | 31 Mar 2026 |
| Peter Kolchinsky |
3/4/5
Director, 10%+ Owner
|
14%
|
$175,340,782
26,975,505 shares
|
+$54,624,378 | 26 Mar 2026 |
| RA Capital Healthcare Fund LP |
3/4/5
Director, 10%+ Owner
|
14%
|
$175,340,782
26,975,505 shares
|
+$54,624,378 | 26 Mar 2026 |
| Rajeev M. Shah |
3/4/5
Director, 10%+ Owner
|
14%
|
$175,340,782
26,975,505 shares
|
+$54,624,378 | 26 Mar 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to buying over the last 12 months. Net value: +$227,760,920.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 35,089,984 | 0 | $218,497,512 | $0 | +$218,497,512 |
| 3-6 | 0 | 61,748 | $0 | $907,810 | -$907,810 |
| 6-9 | 1,471,000 | 1,036,960 | $27,936,688 | $15,138,725 | +$12,797,962 |
| 9-12 | 0 | 264,020 | $0 | $2,626,744 | -$2,626,744 |
Reporting owners
Showing 1-19 of 19 reporting-owner rows connected to Wave Life Sciences Ltd.. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| GSK plc | 10%+ Owner | $346,668,129 | +$27,930,000 | +8.8% | Filing P/S | 11 Dec 2025 |
| RA Capital Healthcare Fund LP | Director, 10%+ Owner | $175,340,782 | +$54,624,378 | +45% | Filing P/S | 26 Mar 2026 |
| Peter Kolchinsky | Director, 10%+ Owner | $175,340,782 | +$54,624,378 | +45% | Filing P/S | 26 Mar 2026 |
| RA CAPITAL MANAGEMENT, L.P. | Director, 10%+ Owner | $175,340,782 | +$54,631,065 | +45% | Filing P/S | 26 Mar 2026 |
| Rajeev M. Shah | Director, 10%+ Owner | $175,340,782 | +$54,624,378 | +45% | Filing P/S | 26 Mar 2026 |
| Ken Takanashi | Director | $163,715,967 | -$42,630 | -0.03% | Mixed | 23 Mar 2026 |
| Chandra Vargeese | Chief Technology Officer, Head of Platform Discovery Sciences | $5,490,908 | -$43,417 | -0.78% | Filing P/S | 05 Feb 2026 |
| Gregory L. Verdine | Director | $3,866,798 | -$369,461 | -8.7% | Filing P/S | 08 Dec 2025 |
| Paul Bolno | President and CEO, Director | $3,705,744 | -$2,335,766 | -39% | Filing P/S | 05 Feb 2026 |
| Kyle Moran | Chief Financial Officer | $1,807,478 | -$4,152,238 | -70% | Filing P/S | 05 Feb 2026 |
| Chris Francis | SVP, Corporate Development, Head of Emerging Areas | $928,005 | -$7,102,264 | -88% | Filing P/S | 26 Feb 2026 |
| Erik Ingelsson | Chief Scientific Officer | $637,022 | Median | 09 Apr 2026 | ||
| Heidi L. Wagner | Director | $629,020 | -$189,000 | -23% | Filing P/S | 08 Dec 2025 |
| Mark Corrigan | Director | $405,282 | -$217,297 | -35% | Filing P/S | 08 Dec 2025 |
| Christopher I. Wright | Chief Medical Officer | $330,785 | Median | 09 Apr 2026 | ||
| Aik Na Tan | Director | $323,850 | -$2,027,270 | -86% | Filing P/S | 08 Dec 2025 |
| Henry Christian O | Director | $228,854 | -$1,454,516 | -86% | Filing P/S | 08 Dec 2025 |
| Adrian Rawcliffe | Director | $190,500 | -$739,421 | -80% | Filing P/S | 08 Dec 2025 |
| Michael A. Panzara | Chief Medical Officer, Head of Therapeutics Discovery and Development | Mixed | 25 Jul 2022 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 3.73% | $6,312,092 | $6.50 | 971,091 | 26,975,505 | 30 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 3.73% | $6,312,092 | $6.50 | 971,091 | 26,975,505 | 30 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 3.73% | $6,312,092 | $6.50 | 971,091 | 26,975,505 | 30 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 3.73% | $6,312,092 | $6.50 | 971,091 | 26,975,505 | 30 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 10.6% | $16,046,856 | $6.43 | 2,495,623 | 26,004,414 | 27 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 10.6% | $16,046,856 | $6.43 | 2,495,623 | 26,004,414 | 27 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 10.6% | $16,046,856 | $6.43 | 2,495,623 | 26,004,414 | 27 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 10.6% | $16,046,856 | $6.43 | 2,495,623 | 26,004,414 | 27 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 29.2% | $32,265,431 | $6.08 | 5,305,782 | 23,508,791 | 26 Mar 2026 | See footnotes |
| RA CAPITAL MANAGEMENT, L.P. | WVE | Ordinary Shares | Purchase | 29.2% | $32,265,431 | $6.08 | 5,305,782 | 23,508,791 | 26 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 29.2% | $32,265,431 | $6.08 | 5,305,782 | 23,508,791 | 26 Mar 2026 | See footnotes |
| Ra Capital Management, L.P. | WVE | Ordinary Shares | Purchase | 29.2% | $32,265,431 | $6.08 | 5,305,782 | 23,508,791 | 26 Mar 2026 | See footnotes |
| Ken Takanashi | WVE | Ordinary Shares | Conversion of derivative security | 68.4% | 3,901,348 | 9,606,408 | 23 Mar 2026 | See Footnote | ||
| Ken Takanashi | WVE | Series A Preferred Shares | Conversion of derivative security | -100% | -3,901,348 | 0 | 23 Mar 2026 | See Footnote | ||
| Chris Francis | WVE | Ordinary Shares | Sale | -34.9% | $499,593 | $15.05 | -33,194 | 61,867 | 26 Feb 2026 | Direct |
| Chris Francis | WVE | Ordinary Shares | Options Exercise | 71.3% | 33,194 | 79,767 | 26 Feb 2026 | Direct | ||
| Chris Francis | WVE | Share Option (right to buy) | Options Exercise | -35.2% | -33,194 | 61,175 | 26 Feb 2026 | Direct | ||
| Kyle Moran | WVE | Ordinary Shares | Sale | -2.6% | $48,259 | $13.45 | -3,588 | 134,385 | 09 Feb 2026 | Direct |
| Paul Bolno | WVE | Ordinary Shares | Sale | -3.66% | $140,956 | $13.45 | -10,480 | 275,520 | 09 Feb 2026 | Direct |
| Chris Francis | WVE | Ordinary Shares | Sale | -2.95% | $25,326 | $13.45 | -1,883 | 61,867 | 09 Feb 2026 | Direct |
| Chandra Vargeese | WVE | Ordinary Shares | Sale | -0.78% | $43,417 | $13.45 | -3,228 | 408,246 | 09 Feb 2026 | Direct |
| Kyle Moran | WVE | Ordinary Shares | Award | 49.4% | 45,625 | 137,973 | 05 Feb 2026 | Direct | ||
| Kyle Moran | WVE | Share Option (right to buy) | Award | 273,750 | 273,750 | 05 Feb 2026 | Direct | |||
| Paul Bolno | WVE | Ordinary Shares | Award | 136.4% | 165,000 | 286,000 | 05 Feb 2026 | Direct | ||
| Paul Bolno | WVE | Share Option (right to buy) | Award | 1,000,000 | 1,000,000 | 05 Feb 2026 | Direct | |||
| Chris Francis | WVE | Ordinary Shares | Award | 155% | 38,750 | 63,750 | 05 Feb 2026 | Direct | ||
| Chris Francis | WVE | Share Option (right to buy) | Award | 232,500 | 232,500 | 05 Feb 2026 | Direct | |||
| Chandra Vargeese | WVE | Ordinary Shares | Award | 12.5% | 45,625 | 411,474 | 05 Feb 2026 | Direct | ||
| Chandra Vargeese | WVE | Share Option (right to buy) | Award | 273,750 | 273,750 | 05 Feb 2026 | Direct | |||
| Chris Francis | WVE | Ordinary Shares | Sale | -27.3% | $150,260 | $16.03 | -9,375 | 25,000 | 02 Jan 2026 | Direct |
| Chris Francis | WVE | Ordinary Shares | Options Exercise | 37.5% | 9,375 | 34,375 | 02 Jan 2026 | Direct | ||
| Chris Francis | WVE | Share Option (right to buy) | Options Exercise | -100% | -9,375 | 0 | 02 Jan 2026 | Direct | ||
| GSK plc | WVE | Ordinary Shares | Purchase | 8.76% | $27,930,000 | $19.00 | 1,470,000 | 18,245,691 | 11 Dec 2025 | By Corporation |
| Kyle Moran | WVE | Ordinary Shares | Sale | -35.9% | $1,001,979 | $20.03 | -50,036 | 89,218 | 09 Dec 2025 | Direct |
| Kyle Moran | WVE | Ordinary Shares | Options Exercise | 161.6% | 86,000 | 139,218 | 09 Dec 2025 | Direct | ||
| Kyle Moran | WVE | Share Option (right to buy) | Award | -100% | -86,000 | 0 | 09 Dec 2025 | Direct | ||
| Heidi L. Wagner | WVE | Ordinary Shares | Sale | -23.8% | $189,000 | $13.50 | -14,000 | 44,930 | 08 Dec 2025 | Direct |
| Heidi L. Wagner | WVE | Ordinary Shares | Options Exercise | 36.9% | 14,000 | 51,930 | 08 Dec 2025 | Direct | ||
| Heidi L. Wagner | WVE | Share Option (right to buy) | Options Exercise | -66.7% | -14,000 | 7,000 | 08 Dec 2025 | Direct | ||
| Aik Na Tan | WVE | Ordinary Shares | Options Exercise | 119,230 | 70,400 | 08 Dec 2025 | Direct | |||
| Aik Na Tan | WVE | Ordinary Shares | Sale | -84.1% | $1,823,158 | $13.58 | -134,218 | 25,400 | 08 Dec 2025 | Direct |
| Aik Na Tan | WVE | Share Option (right to buy) | Options Exercise | -100% | -119,230 | 0 | 08 Dec 2025 | Direct | ||
| Chris Francis | WVE | Ordinary Shares | Sale | -94.6% | $6,427,085 | $14.57 | -441,031 | 25,000 | 08 Dec 2025 | Direct |
| Chris Francis | WVE | Ordinary Shares | Options Exercise | 441,031 | 147,349 | 08 Dec 2025 | Direct | |||
| Chris Francis | WVE | Share Option (right to buy) | Options Exercise | -100% | -441,031 | 0 | 08 Dec 2025 | Direct | ||
| Kyle Moran | WVE | Ordinary Shares | Sale | -70.2% | $3,102,000 | $14.77 | -210,000 | 89,218 | 08 Dec 2025 | Direct |
| Kyle Moran | WVE | Ordinary Shares | Options Exercise | 210,000 | 189,218 | 08 Dec 2025 | Direct | |||
| Kyle Moran | WVE | Share Option (right to buy) | Award | -100% | -210,000 | 0 | 08 Dec 2025 | Direct | ||
| Gregory L. Verdine | WVE | Ordinary Shares | Sale | -6.77% | $269,461 | $13.47 | -20,000 | 275,217 | 08 Dec 2025 | Direct |
| Adrian Rawcliffe | WVE | Ordinary Shares | Sale | -76.8% | $630,000 | $15.00 | -42,000 | 12,700 | 08 Dec 2025 | Direct |