CASI Pharmaceuticals, Inc. - Ordinary Shares, par value US$0.0001 per share (CASI) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2022 to Q3 2025

Type / Class
Equity / Ordinary Shares, par value US$0.0001 per share
Symbol
CASI on Nasdaq
Shares outstanding
20,679,958
Price per share
$0.76
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
2,606,843
Total reported value
$4,327,257
% of total 13F portfolios
0%
Share change
+361,675
Value change
+$649,422
Number of holders
21
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of CASI Pharmaceuticals, Inc. - Ordinary Shares, par value US$0.0001 per share (CASI) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Panacea Innovation Ltd 22% +13% $4,698,042 +$999,856 4,651,527 +27% James Huang 16 Dec 2025
He Wei-Wu 19% 0% $3,687,948 3,965,535 0% WEI-WU HE, Ph.D. 09 Jan 2026
Chen Zhenfeng M 11% $4,150,370 2,255,636 Chen Zhenfeng 30 Sep 2025
Huang James 14% $3,177,509 2,161,571 James Huang 30 Jun 2025
SPARKLE BYTE LTD 5% $775,088 1,019,852 SPARKLE BYTE LTD 30 Sep 2025
Ho Chi Sing 4.8% -27% $754,405 992,638 0% Zhou Quan 30 Sep 2025
Foresite Capital Fund VI LP 6.3% +24% $1,626,727 +$320,106 979,956 +24% Foresite Capital Fund VI LP 30 Sep 2025

As of 30 Sep 2025, 21 institutional investors reported holding 2,606,843 shares of CASI Pharmaceuticals, Inc. - Ordinary Shares, par value US$0.0001 per share (CASI). This represents 13% of the company’s total 20,679,958 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of CASI Pharmaceuticals, Inc. - Ordinary Shares, par value US$0.0001 per share (CASI) together control 13% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
VR ADVISER, LLC 4.8% 987,259 0% 0.09% $1,638,850
Foresite Capital Management VI LLC 4.7% 979,956 +24% 0.63% $1,626,727
BANK OF AMERICA CORP /DE/ 1.2% 254,884 +2013% 0% $423,108
Woodline Partners LP 0.8% 165,640 0% 0% $274,962
Wellington Shields Capital Management, LLC 0.34% 69,535 -23% 0.02% $115,428
RENAISSANCE TECHNOLOGIES LLC 0.21% 43,900 +12% 0% $72,874
TWO SIGMA INVESTMENTS, LP 0.16% 33,267 0% $55,223
Wellington Shields & Co., LLC 0.15% 30,091 0% 0.01% $49,951
GEODE CAPITAL MANAGEMENT, LLC 0.09% 18,808 0% 0% $31,221
Ground Swell Capital, LLC 0.05% 10,135 0.04% $16,824
ROYAL BANK OF CANADA 0.05% 9,700 0% 0% $16,000
GROUP ONE TRADING LLC 0.01% 2,300 0% $3,818
WELLS FARGO & COMPANY/MN 0% 505 0% 0% $838
MORGAN STANLEY 0% 365 0% 0% $606
BlackRock, Inc. 0% 296 0% 0% $491
BNP PARIBAS FINANCIAL MARKETS 0% 134 0% 0% $222
JPMORGAN CHASE & CO 0% 25 0% 0% $42
UBS Group AG 0% 14 -99% 0% $23
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 0% 13 0% 0% $22
Colonial Trust Co / SC 0% 11 0% 0% $18
MAI Capital Management 0% 5 0% 0% $9
TWO SIGMA SECURITIES, LLC 0% 0 -100% $0
CITIGROUP INC 0% 0 -100% $0
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0% 0 -100% $0
ADAR1 Capital Management, LLC 0% 0 -100% $0

Institutional Holders of CASI Pharmaceuticals, Inc. - Ordinary Shares, par value US$0.0001 per share (CASI) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q3 2,606,843 $4,327,257 +$649,422 $1.66 21
2025 Q2 2,245,168 $2,648,852 -$589,075 $1.18 23
2025 Q1 2,744,278 $5,927,688 +$186,001 $2.16 22
2024 Q4 2,658,168 $7,523,090 -$53,802 $2.83 22
2024 Q3 1,322,529 $8,138,853 +$5,984,886 $6.16 20
2024 Q2 352,170 $1,936,256 +$552,357 $5.50 23
2024 Q1 252,002 $909,576 -$261,433 $3.61 20
2023 Q4 275,894 $1,981,066 -$338,820 $7.16 17
2023 Q3 344,608 $882,628 -$268,771 $2.56 18
2023 Q2 449,838 $1,124,376 -$1,180,810 $2.50 18
2023 Q1 929,752 $2,152,582 +$2,152,350 $2.32 19
2022 Q4 100 $179 +$179 $1.79 1