| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BIOTECHNOLOGY VALUE FUND L P | 21.6% | -14.8% | $63,747,357 | -$9,664,913 | 2,590,303 | -13.2% | BVF GP HOLDINGS LLC | 16 May 2025 |
| MORGAN STANLEY | 12.7% | +37.8% | $37,100,087 | +$10,076,968 | 1,525,497 | +37.3% | Morgan Stanley | 30 May 2025 |
| FMR LLC | 9% | $30,120,509 | 1,079,588 | FMR LLC | 30 Jun 2025 | |||
| VANGUARD GROUP INC | 5.33% | $16,095,596 | 638,813 | The Vanguard Group | 30 Jun 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 8,331,130 | $320,376,948 | +$7,190,706 | $38.54 | 73 |
| 2025 Q2 | 8,155,440 | $205,520,031 | +$8,183,948 | $25.2 | 64 |
| 2025 Q1 | 7,851,211 | $156,475,264 | +$931,012 | $19.93 | 63 |
| 2024 Q4 | 7,796,108 | $204,882,543 | +$3,239,811 | $26.28 | 62 |
| 2024 Q3 | 7,671,971 | $203,155,769 | -$135,294 | $26.48 | 66 |
| 2024 Q2 | 7,654,079 | $181,324,839 | +$887,764 | $23.69 | 59 |
| 2024 Q1 | 7,611,625 | $183,060,298 | +$2,664,935 | $24.05 | 56 |
| 2023 Q4 | 7,512,134 | $138,976,045 | -$2,077,799 | $18.5 | 59 |
| 2023 Q3 | 7,640,034 | $107,648,654 | +$264,111 | $14.09 | 52 |
| 2023 Q2 | 7,341,837 | $138,686,545 | +$9,651,005 | $18.89 | 57 |
| 2023 Q1 | 7,053,678 | $148,922,289 | +$10,003,639 | $21.11 | 50 |
| 2022 Q4 | 6,606,407 | $121,556,292 | +$3,654,880 | $18.4 | 46 |
| 2022 Q3 | 6,284,288 | $112,547,939 | +$688,596 | $17.9 | 40 |
| 2022 Q2 | 6,225,270 | $138,694,585 | -$3,097,140 | $22.28 | 39 |
| 2022 Q1 | 6,374,155 | $178,322,717 | -$314,218 | $27.98 | 50 |
| 2021 Q4 | 6,390,954 | $133,233,609 | +$487,105 | $20.84 | 47 |
| 2021 Q3 | 6,330,858 | $156,707,541 | +$961,568 | $24.75 | 44 |
| 2021 Q2 | 6,289,386 | $213,835,368 | -$3,381,231 | $34 | 48 |
| 2021 Q1 | 6,372,543 | $260,057,582 | -$2,572,754 | $40.81 | 58 |
| 2020 Q4 | 6,428,754 | $283,695,723 | +$7,194,225 | $44.13 | 54 |
| 2020 Q3 | 6,317,714 | $119,023,029 | +$237,284 | $18.84 | 51 |
| 2020 Q2 | 6,297,866 | $124,438,168 | +$29,194,757 | $19.76 | 53 |
| 2020 Q1 | 4,812,486 | $97,931,815 | +$4,542,885 | $20.35 | 43 |
| 2019 Q4 | 4,553,112 | $124,240,483 | +$35,543,092 | $27.3 | 47 |
| 2019 Q3 | 3,254,450 | $63,707,425 | -$10,840,262 | $19.68 | 39 |
| 2019 Q2 | 3,900,601 | $57,935,153 | -$3,592,926 | $14.86 | 41 |
| 2019 Q1 | 4,172,450 | $51,659,725 | -$219,272 | $12.38 | 42 |
| 2018 Q4 | 4,184,198 | $52,766,037 | +$6,556,194 | $12.65 | 42 |
| 2018 Q3 | 3,596,507 | $63,197,286 | -$1,404,158 | $17.58 | 55 |
| 2018 Q2 | 3,651,061 | $76,214,925 | +$5,786,427 | $20.88 | 59 |
| 2018 Q1 | 3,386,684 | $68,511,040 | -$9,958 | $20.23 | 53 |
| 2017 Q4 | 3,238,235 | $115,281,071 | +$18,204,997 | $35.6 | 56 |
| 2017 Q3 | 2,727,480 | $53,609,039 | +$4,526,937 | $19.65 | 31 |
| 2017 Q2 | 2,497,780 | $17,457,014 | +$987,616 | $6.99 | 22 |
| 2017 Q1 | 2,354,815 | $16,740,014 | +$10,294,074 | $7.1 | 23 |
| 2016 Q4 | 1,096,967 | $4,626,000 | +$4,609,000 | $4.22 | 28 |
| 2016 Q3 | 30,725 | $14,000 | +$14,000 | $0.4557 | 1 |