LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (LXRX)
CUSIP: 528872302
Q3 2025 13F Holders as of 30 Sep 2025
- Type / Class
- Equity / Common Stock, par value $0.001 per share
- Shares outstanding
- 444,558,533
- Total 13F shares
- 255,139,258
- Share change
- -1,127,208
- Total reported value
- $344,428,817
- Put/Call ratio
- 11%
- Price per share
- $1.35
- Number of holders
- 121
- Value change
- -$1,045,992
- Number of buys
- 44
- Number of sells
- 57
Quarterly Holders Quick Answers
What is CUSIP 528872302?
CUSIP 528872302 identifies LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share in SEC institutional holdings data.
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Recent filing periods for CUSIP 528872302:
Top shareholders of LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Artal Group S.A. |
13F
|
Company |
31%
|
136,180,481
|
$129,371,457 | — | 30 Jun 2025 | |
| Siren, L.L.C. |
3/4/5
13F
|
Director, 10%+ Owner · Individual |
8.8%
from 13F
|
35,402,689
|
$92,755,045 | — | 25 Jul 2024 | |
| FMR LLC |
13F
13D/G
|
Company |
10%
from 13D/G
|
38,137,535
|
$36,066,667 | — | 30 Jun 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
2%
|
8,851,036
|
$8,373,080 | — | 30 Jun 2025 | |
| Invus US Partners LLC |
3/4/5
|
Director, 10%+ Owner |
—
class O/S missing
|
5,782,749
|
$6,090,969 | — | 05 Aug 2022 | |
| Schonfeld Strategic Advisors LLC |
13F
|
Company |
1%
|
4,576,152
|
$4,327,663 | — | 30 Jun 2025 | |
| Lonnel Coats |
3/4/5
|
Chief Executive Officer, Director |
—
mixed-class rows
|
2,109,255
mixed-class rows
|
$3,507,748 | — | 28 Feb 2024 | |
| BlackRock, Inc. |
13F
|
Company |
0.75%
|
3,354,669
|
$3,172,510 | — | 30 Jun 2025 | |
| Sessa Capital IM, L.P. |
13F
|
Company |
0.67%
|
3,000,000
|
$2,837,100 | — | 30 Jun 2025 | |
| GSA CAPITAL PARTNERS LLP |
13F
|
Company |
0.64%
|
2,830,659
|
$2,677,000 | — | 30 Jun 2025 | |
| CIBC Private Wealth Group LLC |
13F
|
Company |
0.55%
|
2,450,400
|
$2,317,343 | — | 30 Jun 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.53%
|
2,377,694
|
$2,249,260 | — | 30 Jun 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.37%
|
1,643,264
|
$1,554,035 | — | 30 Jun 2025 | |
| AQR CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.32%
|
1,402,210
|
$1,326,069 | — | 30 Jun 2025 | |
| Jeffrey L. Wade |
3/4/5
|
President and COO |
—
mixed-class rows
|
729,441
mixed-class rows
|
$1,106,796 | — | 08 Jul 2024 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.2%
|
883,227
|
$835,268 | — | 30 Jun 2025 | |
| STATE STREET CORP |
13F
|
Company |
0.18%
|
818,621
|
$774,170 | — | 30 Jun 2025 | |
| JANE STREET GROUP, LLC |
13F
|
Company |
0.18%
|
804,667
|
$760,973 | — | 30 Jun 2025 | |
| Hennion & Walsh Asset Management, Inc. |
13F
|
Company |
0.18%
|
793,400
|
$750,318 | — | 30 Jun 2025 | |
| ROYAL BANK OF CANADA |
13F
|
Company |
0.17%
|
774,044
|
$732,000 | — | 30 Jun 2025 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.17%
|
755,652
|
$714,620 | — | 30 Jun 2025 | |
| B. Kassler Taub |
3/4/5
|
SVP, Regulatory & QA |
—
mixed-class rows
|
431,995
mixed-class rows
|
$597,845 | — | 28 Feb 2024 | |
| Monaco Asset Management SAM |
13F
|
Company |
0.12%
|
531,600
|
$502,734 | — | 30 Jun 2025 | |
| HRT FINANCIAL LP |
13F
|
Company |
0.11%
|
488,468
|
$461,000 | — | 30 Jun 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
0.11%
|
486,674
|
$460,248 | — | 30 Jun 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.09%
|
420,700
|
$397,856 | — | 30 Jun 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.09%
|
416,372
|
$393,763 | — | 30 Jun 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
0.09%
|
403,922
|
$381,989 | — | 30 Jun 2025 | |
| UBS Group AG |
13F
|
Company |
0.09%
|
400,732
|
$379,092 | — | 30 Jun 2025 | |
| GROUP ONE TRADING LLC |
13F
|
Company |
0.08%
|
346,752
|
$327,923 | — | 30 Jun 2025 | |
| Ph.D. Alan J. Main |
3/4/5
|
EVP, Innov & Chem Sciences |
—
mixed-class rows
|
1,228,681
mixed-class rows
|
$318,646 | — | 28 Feb 2025 | |
| Lombard Odier SCmA Compagnie |
13F
|
Individual |
0.07%
|
330,000
|
$312,081 | — | 30 Jun 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.07%
|
325,746
|
$308,058 | — | 30 Jun 2025 | |
| Brian T. Corrigan |
3/4/5
|
SVP, Regulatory & QA |
—
mixed-class rows
|
1,121,660
mixed-class rows
|
$300,602 | — | 13 Feb 2025 | |
| Thomas Garner |
3/4/5
|
SVP, Chief Commercial Officer |
—
mixed-class rows
|
454,260
mixed-class rows
|
$239,236 | — | 08 Feb 2024 | |
| Robert J. Lefkowitz MD |
3/4/5
|
Director |
—
mixed-class rows
|
130,080
mixed-class rows
|
$223,156 | — | 13 May 2024 | |
| Cerity Partners LLC |
13F
|
Company |
0.05%
|
206,279
|
$195,078 | — | 30 Jun 2025 | |
| IEQ CAPITAL, LLC |
13F
|
Company |
0.04%
|
192,101
|
$181,670 | — | 30 Jun 2025 | |
| Ikarian Capital, LLC |
13F
|
Company |
0.04%
|
176,479
|
$166,897 | — | 30 Jun 2025 | |
| Cubist Systematic Strategies, LLC |
13F
|
Company |
0.04%
|
158,204
|
$149,614 | — | 30 Jun 2025 | |
| Jain Global LLC |
13F
|
Company |
0.03%
|
151,813
|
$143,570 | — | 30 Jun 2025 | |
| Virtu Financial LLC |
13F
|
Company |
0.03%
|
146,805
|
$139,000 | — | 30 Jun 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.03%
|
131,393
|
$124,258 | — | 30 Jun 2025 | |
| Aster Capital Management (DIFC) Ltd |
13F
|
Company |
0.03%
|
130,452
|
$123,368 | — | 30 Jun 2025 | |
| Ph.D. Kiernan Seth |
3/4/5
|
VP, Chief Commercial Officer |
—
mixed-class rows
|
379,163
mixed-class rows
|
$104,343 | — | 28 Feb 2023 | |
| CWM, LLC |
13F
|
Company |
0.02%
|
109,330
|
$103,000 | — | 30 Jun 2025 | |
| LPL Financial LLC |
13F
|
Company |
0.02%
|
104,433
|
$98,762 | — | 30 Jun 2025 | |
| BANK OF MONTREAL /CAN/ |
13F
|
Company |
0.02%
|
100,000
|
$94,570 | — | 30 Jun 2025 | |
| Squarepoint Ops LLC |
13F
|
Company |
0.02%
|
95,617
|
$90,425 | — | 30 Jun 2025 | |
| COMMONWEALTH EQUITY SERVICES, LLC |
13F
|
Company |
0.02%
|
90,864
|
$86,000 | — | 30 Jun 2025 |
Institutional Holders of LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (LXRX) as of Q3 2025
As of 30 Sep 2025,
LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (LXRX) was held by
121 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
255,139,258 shares.
The largest 10 holders included
Artal Group S.A., Siren, L.L.C., FMR LLC, VANGUARD GROUP INC, MILLENNIUM MANAGEMENT LLC, BlackRock, Inc., Sessa Capital IM, L.P., CITADEL ADVISORS LLC, CIBC Private Wealth Group LLC, and GEODE CAPITAL MANAGEMENT, LLC.
This page lists
121
institutional shareholders reporting positions in this security
for the Q3 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q3 2025 vs Q2 2025 Across Filers
Q2 2025 holders
121
Q3 2025 holders
121
Holder diff
0
| Investor | Q2 2025 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q2 2025 Value $ | Q3 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.