Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)

Q: What does CUSIP 48576U106 represent in this 13F holders report?

CUSIP 48576U106 is the security identifier for KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in Q4 2014?

81 institutional investors reported KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share for Q4 2014. Use the holders table for investor-level position and value details.

CUSIP: 48576U106

Q4 2014 13F Holders as of 31 Dec 2014

Type / Class: Equity / Common Stock, par value $0.0001 per share
Shares outstanding: 22,242,217
Total 13F shares: 18,742,387
Share change: +1,329,403
Total reported value: $701,526,058
Put/Call ratio: 133%
Price per share: $37.43
Number of holders: 81
Value change: +$50,285,065
Number of buys: 45
Number of sells: 26

Quarterly Holders Quick Answers

What is CUSIP 48576U106?
CUSIP 48576U106 identifies KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in SEC institutional holdings data.

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Newer quarter: Q1 2015
Previous quarter: Q3 2014

Recent filing periods for CUSIP 48576U106:

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Top shareholders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FRANKLIN RESOURCES INC	13F	Company	20%	4,420,010	$154,433,000	—	30 Sep 2014	13F
FMR LLC	13F	Company	18%	4,059,045	$141,823,000	—	30 Sep 2014	13F
PFM Health Sciences, LP	13F	Company	5.1%	1,125,854	$39,337,000	—	30 Sep 2014	13F
Foresite Capital Management I, LLC	13F	Company	4.8%	1,077,124	$37,635,000	—	30 Sep 2014	13F
BLACKROCK ADVISORS LLC	13F	Company	3.3%	724,165	$25,303,000	—	30 Sep 2014	13F
STATE STREET CORP	13F	Company	2.5%	566,202	$19,775,000	—	30 Sep 2014	13F
SECTORAL ASSET MANAGEMENT INC	13F	Company	2.2%	488,342	$17,063,000	—	30 Sep 2014	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	2.1%	472,146	$16,497,000	—	30 Sep 2014	13F
Cormorant Asset Management, LP	13F	Company	1.7%	385,000	$13,452,000	—	30 Sep 2014	13F
VANGUARD GROUP INC	13F	Company	1.7%	381,197	$13,319,000	—	30 Sep 2014	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	1.5%	328,026	$11,462,000	—	30 Sep 2014	13F
BlackRock Fund Advisors	13F	Company	1.4%	322,396	$11,265,000	—	30 Sep 2014	13F
BlackRock Group LTD	13F	Company	1%	230,817	$8,065,000	—	30 Sep 2014	13F
LORD, ABBETT & CO. LLC	13F	Company	0.75%	166,870	$5,830,000	—	30 Sep 2014	13F
NORTHERN TRUST CORP	13F	Company	0.68%	151,240	$5,284,000	—	30 Sep 2014	13F
BlackRock Institutional Trust Company, N.A.	13F	Company	0.63%	141,013	$4,927,000	—	30 Sep 2014	13F
TCW GROUP INC	13F	Company	0.62%	137,103	$4,790,000	—	30 Sep 2014	13F
BlackRock Finance, Inc.	13F	Company	0.46%	102,655	$3,587,000	—	30 Sep 2014	13F
Tekla Capital Management LLC	13F	Company	0.46%	101,966	$3,563,000	—	30 Sep 2014	13F
PointState Capital LP	13F	Company	0.45%	100,000	$3,494,000	—	30 Sep 2014	13F
BALYASNY ASSET MANAGEMENT L.P.	13F	Company	0.45%	99,631	$3,481,000	—	30 Sep 2014	13F
BAKER BROS. ADVISORS LP	13F	Company	0.42%	94,095	$3,288,000	—	30 Sep 2014	13F
GUGGENHEIM CAPITAL LLC	13F	Company	0.38%	85,143	$2,975,000	—	30 Sep 2014	13F
DEUTSCHE BANK AG\	13F	Company	0.36%	80,047	$2,795,000	—	30 Sep 2014	13F
DRIEHAUS CAPITAL MANAGEMENT LLC	13F	Company	0.35%	78,851	$2,755,000	—	30 Sep 2014	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.35%	77,658	$2,713,000	—	30 Sep 2014	13F
TEACHERS ADVISORS, LLC	13F	Company	0.32%	70,224	$2,454,000	—	30 Sep 2014	13F
BlackRock Investment Management, LLC	13F	Company	0.31%	69,783	$2,438,000	—	30 Sep 2014	13F
EverPoint Asset Management, LLC	13F	Company	0.29%	64,852	$2,266,000	—	30 Sep 2014	13F
Bank of New York Mellon Corp	13F	Company	0.28%	62,885	$2,197,000	—	30 Sep 2014	13F
JPMORGAN CHASE & CO	13F	Company	0.25%	54,550	$1,906,000	—	30 Sep 2014	13F
MORGAN STANLEY	13F	Company	0.22%	48,537	$1,696,000	—	30 Sep 2014	13F
TIAA CREF INVESTMENT MANAGEMENT LLC	13F	Company	0.21%	46,649	$1,630,000	—	30 Sep 2014	13F
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	13F	Company	0.18%	39,980	$1,397,000	—	30 Sep 2014	13F
Point72 Asset Management, L.P.	13F	Company	0.18%	39,400	$1,377,000	—	30 Sep 2014	13F
PICTET ASSET MANAGEMENT LTD	13F	Company	0.16%	35,200	$1,230,000	—	30 Sep 2014	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.14%	30,657	$1,072,000	—	30 Sep 2014	13F
EVENTIDE ASSET MANAGEMENT, LLC	13F	Company	0.13%	30,000	$1,048,000	—	30 Sep 2014	13F
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	13F	Company	0.11%	25,030	$875,000	—	30 Sep 2014	13F
Partner Investment Management, L.P.	13F	Company	0.1%	21,560	$753,000	—	30 Sep 2014	13F
Aperio Group, LLC	13F	Company	0.09%	20,421	$714,000	—	30 Sep 2014	13F
Swiss National Bank	13F	Company	0.09%	19,600	$685,000	—	30 Sep 2014	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.08%	16,718	$584,000	—	30 Sep 2014	13F
UBS AG	13F	Company	0.07%	15,962	$558,000	—	30 Sep 2014	13F
Nationwide Fund Advisors	13F	Company	0.05%	10,345	$361,000	—	30 Sep 2014	13F
RHUMBLINE ADVISERS	13F	Company	0.05%	10,240	$358,000	—	30 Sep 2014	13F
METROPOLITAN LIFE INSURANCE CO/NY	13F	Company	0.04%	9,793	$342,000	—	30 Sep 2014	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.04%	9,555	$334,000	—	30 Sep 2014	13F
MANUFACTURERS LIFE INSURANCE COMPANY, THE	13F	Company	0.04%	8,472	$296,000	—	30 Sep 2014	13F
AMERICAN INTERNATIONAL GROUP, INC.	13F	Company	0.04%	8,111	$283,398	—	30 Sep 2014	13F

Institutional Holders of Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) as of Q4 2014

As of 31 Dec 2014, Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) was held by 81 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 18,742,387 shares. The largest 10 holders included FMR LLC, FRANKLIN RESOURCES INC, Foresite Capital Management I, LLC, Partner Fund Management, L.P., BlackRock Fund Advisors, State Street Corp, BlackRock Advisors LLC, Sectoral Asset Management Inc, ALLIANCEBERNSTEIN L.P., and VANGUARD GROUP INC. This page lists 81 institutional shareholders reporting positions in this security for the Q4 2014 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2014 vs Q3 2014 Across Filers

Q3 2014 holders

Q4 2014 holders

Holder diff

Investor	Q3 2014 Shares	Q4 2014 Shares	Share Diff	Share Chg %	Q3 2014 Value $	Q4 2014 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.