89bio, Inc. - Common stock, par value $0.001 per share (ETNB)

CUSIP: 282559103

Q4 2025 13F Holders as of 31 Dec 2025

Holder snapshot 5 signals
Share change
-154,510,200
SEC-reported price per share
$13.56
Number of holders
2
Value change
-$2,271,221,420
Number of sells
193
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
148,275,293

Security key

282559103

Report period

Q4 2025

Institutions

2

Top holders

2

Ownership snapshot

Top reported holders of ETNB - 89bio, Inc. - Common stock, par value $0.001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
VANGUARD GROUP INC
Disclosed value leader
RA CAPITAL MANAGEMENT, L.P.
Comparable rows
15/15
Latest evidence
30 Sep 2025
13F 13D/G 3/4/5 Lead comparable stake: 5.6% 13D/G row: VANGUARD GROUP INC Showing 1-6 of 15 holder rows.

Quick read

VANGUARD GROUP INC leads the comparable SEC ownership view at 5.6%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens VANGUARD GROUP INC's linked filing trail.
Comparable ownership Top 5
VANGUARD GROUP INC 5.6%
SUVRETTA CAPITAL MANAGEMENT, LLC 5.6%
Janus Henderson Group Ltd. 3.6%
BIOTECHNOLOGY VALUE FUND L P 3.6%
RTW INVESTMENTS, LP 1.3%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
VANGUARD GROUP INC
13F 13D/G
Company · The Vanguard Group
5.6%
from 13D/G
$118,385,847
8,053,459 shares
30 Sep 2025
SUVRETTA CAPITAL MANAGEMENT, LLC
13D/G 13F
Company
5.6%
$121,716,000
8,280,000 shares
-$93,071,712 30 Sep 2025
Janus Henderson Group Ltd.
13D/G 13F
JANUS HENDERSON GROUP PLC · Company
3.6%
$79,060,933
5,378,185 shares
-$226,534,240 30 Sep 2025
BIOTECHNOLOGY VALUE FUND L P
13D/G
BVF PARTNERS L P/IL
3.6%
$29,903,806
4,333,885 shares
$0 31 Dec 2024
RTW INVESTMENTS, LP
13D/G
1.3%
$13,575,936
1,967,527 shares
$0 31 Mar 2025
RA CAPITAL MANAGEMENT, L.P.
13F 3/4/5
Company · Director, 10%+ Owner
13%
$292,378,340
19,889,683 shares
30 Sep 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
2
Shares
90,017
Rows available
2
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
197
Q4 2025 holders
2
Holder diff
-195
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 value Q4 2025 value Value change Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
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