Disc Medicine, Inc. - Common Stock, $0.0001 par value per share (IRON)

CUSIP: 254604101

Q4 2025 13F Holders as of 31 Dec 2025

Type / Class
Equity / Common Stock, $0.0001 par value per share
Shares outstanding
37,778,373
Total 13F shares
38,292,771
Share change
+3,887,626
Total reported value
$3,040,405,091
Put/Call ratio
321%
Price per share
$79.41
Number of holders
195
Value change
+$327,723,771
Number of buys
120
Number of sells
59

Security key

254604101

Report period

Q4 2025

Institutions

195

Top holders

10

Top shareholders of IRON - Disc Medicine, Inc. - Common Stock, $0.0001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
FMR LLC
13F 13D/G
Company
14%
from 13D/G
4,935,159
$326,115,306 30 Sep 2025
AI DMI LLC
3/4/5 13D/G
10%+ Owner
8%
from 13D/G
2,814,379
$226,473,078 -$59,873,462 22 Oct 2025
RA CAPITAL MANAGEMENT, L.P.
13D/G 13F
Company
5.9%
2,228,924
$177,001,530 $0 30 Dec 2025
ORBIMED ADVISORS LLC
13F 13D/G 3/4/5
Company · Director
4.5%
from 13D/G
1,415,020
$93,504,522 30 Sep 2025
WELLINGTON MANAGEMENT GROUP LLP
13F 13D/G
Company
4.1%
from 13D/G
1,410,077
$93,177,887 30 Sep 2025
Paradigm Biocapital Advisors LP
13D/G 13F
Company
3.5%
1,210,971
$57,097,283 $0 31 Mar 2025
Bain Capital Life Sciences Opportunities III, LP
13D/G
3.3%
983,500
$46,372,025 $0 31 Dec 2024
Frazier Life Sciences Public Fund, L.P.
13D/G
3%
1,026,489
$57,339,676 $0 30 Jun 2025
Atlas Venture Fund X, L.P.
3/4/5 13D/G
10%+ Owner
2.2%
from 13D/G
1,600,512
$108,274,637 23 Jan 2024
Kevin Bitterman
3/4/5
Director
0.04%
14,013
$1,281,769 -$36,590,630 17 Dec 2025
Atlas Venture Life Science Advisors, LLC
13F
Company
5.7%
2,142,617
$141,584,131 30 Sep 2025
13F
BlackRock, Inc.
13F
Company
5.3%
2,019,283
$133,434,221 30 Sep 2025
13F
VANGUARD GROUP INC
13F
Company
3.8%
1,448,059
$95,687,738 30 Sep 2025
13F
Frazier Life Sciences Management, L.P.
13F
Company
3.8%
1,438,534
$95,058,327 30 Sep 2025
13F
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
3.5%
1,326,429
$87,651,000 30 Sep 2025
13F
STATE STREET CORP
13F
Company
2.8%
1,045,597
$69,093,050 30 Sep 2025
13F
DEERFIELD MANAGEMENT COMPANY, L.P.
13F
Company
2.4%
919,403
$60,754,150 30 Sep 2025
13F
Siren, L.L.C.
13F
Individual
2.4%
913,401
$60,357,538 30 Sep 2025
13F
Woodline Partners LP
13F
Company
2.3%
866,955
$57,288,386 30 Sep 2025
13F
JPMORGAN CHASE & CO
13F
Company
2%
752,879
$49,750,244 30 Sep 2025
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
1.7%
628,151
$41,515,834 30 Sep 2025
13F
GOLDMAN SACHS GROUP INC
13F
Company
1.4%
529,081
$34,961,672 30 Sep 2025
13F
Vestal Point Capital, LP
13F
Company
1.3%
500,000
$33,040,000 30 Sep 2025
13F
TCG Crossover Management, LLC
13F
Company
1.2%
465,257
$30,744,183 30 Sep 2025
13F
ADAGE CAPITAL PARTNERS GP, L.L.C.
13F
Company
1.2%
450,000
$29,736,000 30 Sep 2025
13F
Logos Global Management LP
13F
Company
1.2%
450,000
$29,736,000 30 Sep 2025
13F
ARMISTICE CAPITAL, LLC
13F
Company
1.2%
436,000
$28,810,880 30 Sep 2025
13F
Checkpoint Capital L.P.
13F
Company
1.1%
430,000
$28,414,400 30 Sep 2025
13F
First Turn Management, LLC
13F
Company
1.1%
397,693
$26,279,553 30 Sep 2025
13F
JANUS HENDERSON GROUP PLC
13F
Company
0.96%
361,704
$23,901,085 30 Sep 2025
13F
Saturn V Capital Management LP
13F
Company
0.9%
340,897
$22,526,474 30 Sep 2025
13F
BALYASNY ASSET MANAGEMENT L.P.
13F
Company
0.89%
338,101
$22,341,714 30 Sep 2025
13F
BAKER BROS. ADVISORS LP
13F
Company
0.89%
337,050
$22,272,264 30 Sep 2025
13F
EVENTIDE ASSET MANAGEMENT, LLC
13F
Company
0.82%
308,043
$20,355,468 30 Sep 2025
13F
Foresite Capital Management V, LLC
13F
Company
0.79%
299,069
$19,762,480 30 Sep 2025
13F
Nantahala Capital Management, LLC
13F
Company
0.76%
287,800
$19,017,824 30 Sep 2025
13F
Sio Capital Management, LLC
13F
Company
0.75%
284,787
$18,818,725 30 Sep 2025
13F
First Light Asset Management, LLC
13F
Company
0.61%
231,186
$15,276,771 30 Sep 2025
13F
DIMENSIONAL FUND ADVISORS LP
13F
Company
0.61%
230,423
$15,223,560 30 Sep 2025
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.6%
226,655
$14,977,362 30 Sep 2025
13F
Palo Alto Investors LP
13F
Company
0.59%
224,300
$14,821,744 30 Sep 2025
13F
NORTHERN TRUST CORP
13F
Company
0.58%
219,489
$14,503,833 30 Sep 2025
13F
Catalio Capital Management, LP
13F
Company
0.57%
216,527
$14,308,104 30 Sep 2025
13F
Opaleye Management Inc.
13F
Company
0.51%
193,773
$12,804,520 30 Sep 2025
13F
TimesSquare Capital Management, LLC
13F
Company
0.48%
182,170
$12,037,794 30 Sep 2025
13F
Ensign Peak Advisors, Inc
13F
Company
0.47%
177,050
$11,699,464 30 Sep 2025
13F
UBS Group AG
13F
Company
0.45%
171,623
$11,340,848 30 Sep 2025
13F
BANK OF AMERICA CORP /DE/
13F
Company
0.43%
161,184
$10,651,038 30 Sep 2025
13F
MILLENNIUM MANAGEMENT LLC
13F
Company
0.43%
161,000
$10,638,880 30 Sep 2025
13F
VICTORY CAPITAL MANAGEMENT INC
13F
Company
0.4%
149,864
$9,903,013 30 Sep 2025
13F

Institutional Holders of Disc Medicine, Inc. - Common Stock, $0.0001 par value per share (IRON) as of Q4 2025

As of 31 Dec 2025, Disc Medicine, Inc. - Common Stock, $0.0001 par value per share (IRON) was held by 195 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 38,292,771 shares. The largest 10 holders included FMR LLC, BlackRock, Inc., RA CAPITAL MANAGEMENT, L.P., VANGUARD GROUP INC, PRICE T ROWE ASSOCIATES INC /MD/, JPMORGAN CHASE & CO, WELLINGTON MANAGEMENT GROUP LLP, Atlas Venture Life Science Advisors, LLC, Frazier Life Sciences Management, L.P., and STATE STREET CORP. This page lists 195 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
164
Q4 2025 holders
195
Holder diff
31
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 Value $ Q4 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
We use cookies and similar technologies to provide certain features, enhance the user experience and, if you allow them, measure engagement and deliver advertising. Analytics and marketing storage stay off until you grant consent. By clicking on "Agree and continue", you declare your consent to the use of the selected optional cookies. Here you can make detailed settings or revoke your consent (in part if necessary) with effect for the future. For further information, please refer to our Privacy Policy .