Security key
254604101
CUSIP: 254604101
Security key
254604101
Report period
Q4 2025
Institutions
195
Top holders
10
Broader feeds
Reporting periods
Recent filing periods:
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| FMR LLC |
13F
13D/G
|
Company |
14%
from 13D/G
|
4,935,159
|
$326,115,306 | — | 30 Sep 2025 | |
| AI DMI LLC |
3/4/5
13D/G
|
10%+ Owner |
8%
from 13D/G
|
2,814,379
|
$226,473,078 | -$59,873,462 | 22 Oct 2025 | |
| RA CAPITAL MANAGEMENT, L.P. |
13D/G
13F
|
Company |
5.9%
|
2,228,924
|
$177,001,530 | $0 | 30 Dec 2025 | |
| ORBIMED ADVISORS LLC |
13F
13D/G
3/4/5
|
Company · Director |
4.5%
from 13D/G
|
1,415,020
|
$93,504,522 | — | 30 Sep 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
13D/G
|
Company |
4.1%
from 13D/G
|
1,410,077
|
$93,177,887 | — | 30 Sep 2025 | |
| Paradigm Biocapital Advisors LP |
13D/G
13F
|
Company |
3.5%
|
1,210,971
|
$57,097,283 | $0 | 31 Mar 2025 | |
| Bain Capital Life Sciences Opportunities III, LP |
13D/G
|
— |
3.3%
|
983,500
|
$46,372,025 | $0 | 31 Dec 2024 | |
| Frazier Life Sciences Public Fund, L.P. |
13D/G
|
— |
3%
|
1,026,489
|
$57,339,676 | $0 | 30 Jun 2025 | |
| Atlas Venture Fund X, L.P. |
3/4/5
13D/G
|
10%+ Owner |
2.2%
from 13D/G
|
1,600,512
|
$108,274,637 | — | 23 Jan 2024 | |
| Kevin Bitterman |
3/4/5
|
Director |
0.04%
|
14,013
|
$1,281,769 | -$36,590,630 | 17 Dec 2025 | |
| Atlas Venture Life Science Advisors, LLC |
13F
|
Company |
5.7%
|
2,142,617
|
$141,584,131 | — | 30 Sep 2025 | |
| BlackRock, Inc. |
13F
|
Company |
5.3%
|
2,019,283
|
$133,434,221 | — | 30 Sep 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
3.8%
|
1,448,059
|
$95,687,738 | — | 30 Sep 2025 | |
| Frazier Life Sciences Management, L.P. |
13F
|
Company |
3.8%
|
1,438,534
|
$95,058,327 | — | 30 Sep 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
3.5%
|
1,326,429
|
$87,651,000 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
2.8%
|
1,045,597
|
$69,093,050 | — | 30 Sep 2025 | |
| DEERFIELD MANAGEMENT COMPANY, L.P. |
13F
|
Company |
2.4%
|
919,403
|
$60,754,150 | — | 30 Sep 2025 | |
| Siren, L.L.C. |
13F
|
Individual |
2.4%
|
913,401
|
$60,357,538 | — | 30 Sep 2025 | |
| Woodline Partners LP |
13F
|
Company |
2.3%
|
866,955
|
$57,288,386 | — | 30 Sep 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
2%
|
752,879
|
$49,750,244 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.7%
|
628,151
|
$41,515,834 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
1.4%
|
529,081
|
$34,961,672 | — | 30 Sep 2025 | |
| Vestal Point Capital, LP |
13F
|
Company |
1.3%
|
500,000
|
$33,040,000 | — | 30 Sep 2025 | |
| TCG Crossover Management, LLC |
13F
|
Company |
1.2%
|
465,257
|
$30,744,183 | — | 30 Sep 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
1.2%
|
450,000
|
$29,736,000 | — | 30 Sep 2025 | |
| Logos Global Management LP |
13F
|
Company |
1.2%
|
450,000
|
$29,736,000 | — | 30 Sep 2025 | |
| ARMISTICE CAPITAL, LLC |
13F
|
Company |
1.2%
|
436,000
|
$28,810,880 | — | 30 Sep 2025 | |
| Checkpoint Capital L.P. |
13F
|
Company |
1.1%
|
430,000
|
$28,414,400 | — | 30 Sep 2025 | |
| First Turn Management, LLC |
13F
|
Company |
1.1%
|
397,693
|
$26,279,553 | — | 30 Sep 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
0.96%
|
361,704
|
$23,901,085 | — | 30 Sep 2025 | |
| Saturn V Capital Management LP |
13F
|
Company |
0.9%
|
340,897
|
$22,526,474 | — | 30 Sep 2025 | |
| BALYASNY ASSET MANAGEMENT L.P. |
13F
|
Company |
0.89%
|
338,101
|
$22,341,714 | — | 30 Sep 2025 | |
| BAKER BROS. ADVISORS LP |
13F
|
Company |
0.89%
|
337,050
|
$22,272,264 | — | 30 Sep 2025 | |
| EVENTIDE ASSET MANAGEMENT, LLC |
13F
|
Company |
0.82%
|
308,043
|
$20,355,468 | — | 30 Sep 2025 | |
| Foresite Capital Management V, LLC |
13F
|
Company |
0.79%
|
299,069
|
$19,762,480 | — | 30 Sep 2025 | |
| Nantahala Capital Management, LLC |
13F
|
Company |
0.76%
|
287,800
|
$19,017,824 | — | 30 Sep 2025 | |
| Sio Capital Management, LLC |
13F
|
Company |
0.75%
|
284,787
|
$18,818,725 | — | 30 Sep 2025 | |
| First Light Asset Management, LLC |
13F
|
Company |
0.61%
|
231,186
|
$15,276,771 | — | 30 Sep 2025 | |
| DIMENSIONAL FUND ADVISORS LP |
13F
|
Company |
0.61%
|
230,423
|
$15,223,560 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.6%
|
226,655
|
$14,977,362 | — | 30 Sep 2025 | |
| Palo Alto Investors LP |
13F
|
Company |
0.59%
|
224,300
|
$14,821,744 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.58%
|
219,489
|
$14,503,833 | — | 30 Sep 2025 | |
| Catalio Capital Management, LP |
13F
|
Company |
0.57%
|
216,527
|
$14,308,104 | — | 30 Sep 2025 | |
| Opaleye Management Inc. |
13F
|
Company |
0.51%
|
193,773
|
$12,804,520 | — | 30 Sep 2025 | |
| TimesSquare Capital Management, LLC |
13F
|
Company |
0.48%
|
182,170
|
$12,037,794 | — | 30 Sep 2025 | |
| Ensign Peak Advisors, Inc |
13F
|
Company |
0.47%
|
177,050
|
$11,699,464 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
0.45%
|
171,623
|
$11,340,848 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.43%
|
161,184
|
$10,651,038 | — | 30 Sep 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.43%
|
161,000
|
$10,638,880 | — | 30 Sep 2025 | |
| VICTORY CAPITAL MANAGEMENT INC |
13F
|
Company |
0.4%
|
149,864
|
$9,903,013 | — | 30 Sep 2025 |
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).