Security Snapshot

Disc Medicine, Inc. - Common Stock, $0.0001 par value per share (IRON) Institutional Ownership

CUSIP: 254604101

13F Institutional Holders and Ownership History from Q4 2022 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

201

Shares (Excl. Options)

41,790,891

Price

$63.94

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Latest holder snapshot 5 signals
Portfolio coverage rank
0.01%
Share change
+3,426,875
Value change
+$184,842,449
Number of holders
201
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
37,778,373
SEC-reported price per share
$70.03
Insider filing price
$70.03
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • IRON - Disc Medicine, Inc. - Common Stock, $0.0001 par value per share is tracked under CUSIP 254604101.
  • 201 institutions reported positions in Q1 2026.
  • 9 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 195 to 201 between Q4 2025 and Q1 2026.
  • SEC-reported value moved from $3,040,405,091 to $2,667,822,262.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 201 institutions filings for Q1 2026.

Open SEC evidence

Security key

254604101

Latest holder period

Q1 2026

13F holders

201

13D/G owners

9

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
9
Security
IRON
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
FMR LLC 14% +16% $324,265,066 +$45,337,554 4,907,159 +16% FMR LLC 30 Sep 2025
AI DMI LLC 8% -25% $199,459,837 -$49,166,626 3,018,460 -20% AI DMI LLC 20 Oct 2025
RA CAPITAL MANAGEMENT, L.P. 5.9% $177,001,530 2,228,924 RA Capital Management, L.P. 30 Dec 2025
ORBIMED ADVISORS LLC 4.5% $73,382,798 1,556,369 ORBIMED ADVISORS LLC 10 Mar 2025
WELLINGTON MANAGEMENT GROUP LLP 4.1% -39% $79,996,547 -$50,911,307 1,432,090 -39% Wellington Management Group LLP 30 Jun 2025
Paradigm Biocapital Advisors LP 3.5% $57,097,283 1,210,971 Paradigm BioCapital Advisors LP 31 Mar 2025
Frazier Life Sciences Public Fund, L.P. 3% $57,339,676 1,026,489 Frazier Life Sciences Public Fund, L.P. 30 Jun 2025
Bain Capital Life Sciences Opportunities III, LP 3.3% $46,372,025 983,500 Bain Capital Life Sciences Opportunities III, LP 31 Dec 2024
Atlas Venture Fund X, L.P. 2.2% -30% $73,469,638 -$24,517,376 813,167 -25% Atlas Venture Fund X, L.P. 12 Dec 2025

As of 31 Mar 2026, 201 institutional investors reported holding 41,790,891 shares of Disc Medicine, Inc. - Common Stock, $0.0001 par value per share (IRON). This represents 111% of the company’s total 37,778,373 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
86%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
FMR LLC 15% 5,586,894 +2.5% 0.02% $357,226,003
RA CAPITAL MANAGEMENT, L.P. 6.5% 2,450,221 +24% 1.7% $156,667,131
BlackRock, Inc. 6% 2,273,831 -0.05% 0% $145,388,755
WELLINGTON MANAGEMENT GROUP LLP 4.6% 1,735,376 +14% 0.02% $110,959,941
STATE STREET CORP 4.5% 1,698,244 +43% 0% $108,585,721
PRICE T ROWE ASSOCIATES INC /MD/ 4.1% 1,549,350 -8.8% 0.01% $99,067,000
Atlas Venture Life Science Advisors, LLC 4% 1,513,875 0% 12% $96,797,168
VANGUARD CAPITAL MANAGEMENT LLC 3.6% 1,375,430 0% 0% $87,944,994
JPMORGAN CHASE & CO 3.6% 1,371,480 -13% 0.01% $83,358,592
Frazier Life Sciences Management, L.P. 3.6% 1,354,852 +7.5% 2.2% $86,629,237
TCG Crossover Management, LLC 3.6% 1,341,862 2.5% $85,798,656
BVF INC/IL 3.4% 1,272,312 +96% 2.6% $81,351,629
ORBIMED ADVISORS LLC 2.8% 1,067,550 0% 1.5% $68,259,147
Siren, L.L.C. 2.6% 988,401 0% 1.8% $63,198,360
Woodline Partners LP 2.5% 958,281 +0.05% 0.23% $61,272,487
GEODE CAPITAL MANAGEMENT, LLC 2% 744,222 +8.7% 0% $47,595,151
Vestal Point Capital, LP 1.9% 700,000 -4.8% 1.3% $44,758,000
DEERFIELD MANAGEMENT COMPANY, L.P. 1.7% 657,000 +29% 0.5% $42,008,580
GOLDMAN SACHS GROUP INC 1.7% 639,842 -15% 0.01% $40,911,498
JENNISON ASSOCIATES LLC 1.6% 610,382 +15% 0.03% $39,027,825
Logos Global Management LP 1.5% 560,000 +9.8% 1.8% $35,806,400
Assenagon Asset Management S.A. 1.4% 546,247 +53% 0.06% $34,927,033
ARMISTICE CAPITAL, LLC 1.4% 536,000 +7.3% 1.1% $34,271,840
Bellevue Group AG 1.2% 459,314 0.7% $29,368,537
Saturn V Capital Management LP 1.2% 449,926 +51% 5.2% $28,768,268

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
14
Latest
Q1 2026
Rows shown
1-14 of 14
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 41,790,891 $2,667,822,262 +$184,842,449 $63.94 201
2025 Q4 38,292,771 $3,040,405,091 +$327,723,771 $79.41 195
2025 Q3 34,174,573 $2,258,188,476 +$16,098,753 $66.08 164
2025 Q2 34,069,403 $1,804,405,782 +$52,373,227 $52.96 148
2025 Q1 33,154,047 $1,649,828,469 +$313,979,403 $49.64 155
2024 Q4 26,576,603 $1,684,756,023 -$53,215,124 $63.40 151
2024 Q3 27,309,249 $1,342,089,295 -$26,632,908 $49.14 130
2024 Q2 27,576,793 $1,242,993,864 +$212,594,407 $45.07 119
2024 Q1 22,155,328 $1,379,374,874 +$124,372,681 $62.26 125
2023 Q4 20,197,167 $1,166,592,879 +$18,737,189 $57.76 111
2023 Q3 19,879,838 $933,957,855 +$42,877,645 $46.98 90
2023 Q2 19,115,397 $848,710,699 +$223,083,623 $44.40 89
2023 Q1 14,612,435 $309,637,635 +$77,103,451 $21.19 45
2022 Q4 10,800,037 $214,639,221 +$202,496,221 $19.89 30
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