Marcio Souza

Insider Reports History

Location: South Plainfield, NJ
Signature: /s/ Alex Nemiroff, as Attorney-in-Fact
All insider transactions: Transactions in reports broken out by “transaction date” reported in original SEC filing, see here for transactions aggregated across transaction date

Holdings reported by Marcio Souza:

Form 4 holding Chief Executive Officer, Director

Praxis Precision Medicines, Inc.

Security class: Common Stock
Shares / value: 76,890
Estimated value: $22,178,920
Report date: 10 Jan 2026
Price: $288.45
Ownership: Direct

Form 4 holding Chief Executive Officer, Director

Praxis Precision Medicines, Inc.

Security class: Common Stock
Shares / value: 2,600
Estimated value: $766,323
Report date: 08 Jan 2026
Price: $294.74
Ownership: Held by spouse

Form 4 holding Director

Aeglea BioTherapeutics, Inc.

Security class: Common Stock
Shares / value: 90,000
Estimated value: $63,900
Report date: 25 Aug 2022
Price: $0.7100
Ownership: Direct

Form 4 holding Chief Executive Officer, Director

Praxis Precision Medicines, Inc.

Security class: Stock Option (Right to Buy)
Shares / value: 22,110
Estimated value
Report date: 08 Jan 2026
Price
Ownership: Direct
Underlying class: Common Stock
Underlying amount

Insider Reports Filed by Marcio Souza

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 08 Jan 2026
Transactions: 3
Transaction value: -$1,226,489
Filing time: 12 Jan 2026, 17:48
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 07 Jan 2026
Transactions: 1
Transaction value: -$118,515
Filing time: 09 Jan 2026, 16:46
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 30 Dec 2025
Transactions: 1
Transaction value: $0
Filing time: 31 Dec 2025, 19:17
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 14 May 2025
Transactions: 1
Transaction value: +$10,974
Filing time: 19 May 2025, 16:57
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 12 Feb 2025
Transactions: 1
Transaction value: -$34,245
Filing time: 14 Feb 2025, 16:29
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 10 Jan 2025
Transactions: 2
Transaction value: $0
Filing time: 14 Jan 2025, 18:50
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 07 Jan 2025
Transactions: 1
Transaction value: -$33,644
Filing time: 08 Jan 2025, 19:50
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 29 Jul 2024
Transactions: 1
Transaction value: $0
Filing time: 31 Jul 2024, 21:03
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 14 May 2024
Transactions: 1
Transaction value: +$21,248
Filing time: 20 May 2024, 08:10
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 12 Feb 2024
Transactions: 1
Transaction value: -$12,100
Filing time: 14 Feb 2024, 16:10
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 12 Jan 2024
Transactions: 1
Transaction value: $0
Filing time: 17 Jan 2024, 16:49
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 07 Jan 2024
Transactions: 1
Transaction value: -$10,529
Filing time: 09 Jan 2024, 21:09
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 27 Jun 2023
Transactions: 1
Transaction value: +$10,587
Filing time: 27 Jun 2023, 19:52
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 12 May 2023
Transactions: 1
Transaction value: +$10,331
Filing time: 18 May 2023, 21:47
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 23 Mar 2023
Transactions: 2
Transaction value: +$60,366
Filing time: 27 Mar 2023, 13:12
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 12 Jan 2023
Transactions: 1
Transaction value: $0
Filing time: 17 Jan 2023, 18:34
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 12 Jan 2023
Transactions: 1
Transaction value: $0
Filing time: 13 Jan 2023, 06:47
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 14 Nov 2022
Transactions: 1
Transaction value: +$3,830
Filing time: 21 Nov 2022, 05:07
Role: Chief Executive Officer, Director
Next action: Open filing details

4 SYRE

Aeglea BioTherapeutics, Inc.

Report period: 25 Aug 2022
Transactions: 1
Transaction value: +$50,472
Filing time: 25 Aug 2022, 19:37
Role: Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 22 Jun 2022
Transactions: 1
Transaction value: $0
Filing time: 24 Jun 2022, 16:45
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 08 Jun 2022
Transactions: 1
Transaction value: +$49,888
Filing time: 09 Jun 2022, 19:25
Role: Chief Executive Officer, Director
Next action: Open filing details

4 SYRE

Aeglea BioTherapeutics, Inc.

Report period: 07 Jun 2022
Transactions: 1
Transaction value: $0
Filing time: 09 Jun 2022, 21:21
Role: Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 13 May 2022
Transactions: 1
Transaction value: +$12,247
Filing time: 18 May 2022, 17:39
Role: Chief Executive Officer, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 07 Jan 2022
Transactions: 2
Transaction value: $0
Filing time: 11 Jan 2022, 15:09
Role: President and CEO, Director
Next action: Open filing details

4 PRAX

Praxis Precision Medicines, Inc.

Report period: 18 Aug 2021
Transactions: 1
Transaction value: +$150,668
Filing time: 19 Aug 2021, 18:33
Role: Chief Executive Officer, Director
Next action: Open filing details

4 SYRE

Aeglea BioTherapeutics, Inc.

Report period: 18 Jun 2021
Transactions: 1
Transaction value: $0
Filing time: 22 Jun 2021, 16:07
Role: Director
Next action: Open filing details

3 SYRE

Aeglea BioTherapeutics, Inc.

Report period: 18 Jun 2021
Transactions: 0
Transaction value: $0
Filing time: 22 Jun 2021, 16:06
Role: Director
Next action: Open filing details

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