| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Souza Marcio | Chief Executive Officer, Director | C/O PRAXIS PRECISION MEDICINES, INC., 99 HIGH STREET, 30TH FLOOR, BOSTON | /s/ Alex Nemiroff, as Attorney-in-Fact | 31 Dec 2025 | 0001707657 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PRAX | Common Stock | Gift | $0 | -400 | -13% | $0.000000 | 2,600 | 30 Dec 2025 | Held by spouse | F1 |
| holding | PRAX | Common Stock | 53,907 | 30 Dec 2025 | Direct |
| Id | Content |
|---|---|
| F1 | Shares were transferred as a gift to a charitable fund. |