Marcio Souza - 14 May 2025 Form 4 Insider Report for Praxis Precision Medicines, Inc. (PRAX)

Role: Chief Executive Officer, Director
Signature: /s/ Alex Nemiroff, as Attorney-in-Fact
Issuer symbol: PRAX
Transactions as of: 14 May 2025
Net transactions value: +$10,974
Form type: 4
Filing time: 19 May 2025, 16:57:11 UTC
Previous filing: 14 Feb 2025
Next filing: 31 Dec 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Souza Marcio	Chief Executive Officer, Director	C/O PRAXIS PRECISION MEDICINES, INC., 99 HIGH STREET, 30TH FLOOR, BOSTON	/s/ Alex Nemiroff, as Attorney-in-Fact	19 May 2025	0001707657

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	PRAX	Common Stock	Award	$10,974	+348	+0.65%	$31.54	53,907	14 May 2025	Direct	F1
holding	PRAX	Common Stock						3,000	14 May 2025	Held by spouse

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	These shares were acquired under the Praxis Precision Medicines, Inc. Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c).