SEC ownership of Crinetics Pharmaceuticals, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001658247.

Holder evidence

50

Lead holder

FMR LLC

13D/G signal

FMR LLC

Latest evidence

31 Mar 2026

Issuer identity
CIK
0001658247
Location
San Diego, CA
Ownership snapshot
Latest large-stake holder
FMR LLC
Latest evidence date
31 Mar 2026

Ownership snapshot

Top shareholders of Crinetics Pharmaceuticals, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Lead holder
FMR LLC
13D/G signal
FMR LLC
Evidence rows
50
Latest as of
31 Mar 2026
13F 13D/G Lead comparable stake: 15% 13D/G row: FMR LLC Showing 1-8 of 50 holder rows.
Holder Evidence Ownership % Position 12M Net Δ As of
FMR LLC
13F 13D/G
Company
15%
from 13D/G
$572,395,895
15,759,799 shares
31 Mar 2026
Farallon Capital Partners, L.P.
13D/G
Dapice Joshua J.
8.5%
$373,521,762
8,024,098 shares
+$111,673,450 31 Dec 2025
WELLINGTON MANAGEMENT GROUP LLP
13D/G 13F
Company
7.8%
$321,720,126
8,157,204 shares
-$8,865,599 31 Mar 2026
DRIEHAUS CAPITAL MANAGEMENT LLC
13D/G 13F
Company
6.1%
$252,255,164
6,395,922 shares
$0 31 Mar 2026
VANGUARD CAPITAL MANAGEMENT LLC
13D/G 13F
Vanguard Capital Management · Company
5.2%
$197,604,263
5,440,646 shares
$0 31 Mar 2026
PRICE T ROWE ASSOCIATES INC /MD/
13D/G 13F
T. Rowe Price Associates, Inc. · Company
5.1%
$211,201,634
5,355,011 shares
$0 31 Mar 2026
BlackRock, Inc.
13F
Company
13F
8.1%
$307,950,573
8,478,815 shares
31 Mar 2026
FARALLON CAPITAL MANAGEMENT LLC
13F
Company
13F
7.9%
$302,839,719
8,338,098 shares
31 Mar 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$11,655,322.

Buys
$0
Insiders: 0
Sells
$11,655,322
Insiders: 9
Net
-$11,655,322
Shares: -318,855
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 318,855
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 142,380 $0 $5,569,647 -$5,569,647
3-6 0 7,500 $0 $362,600 -$362,600
6-9 0 35,000 $0 $1,478,862 -$1,478,862
9-12 0 133,975 $0 $4,244,214 -$4,244,214

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-18 of 18 reporting-owner rows connected to Crinetics Pharmaceuticals, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
18
Lead holder
PERCEPTIVE ADVISORS LLC
Net 12M change
-$11,655,323
Latest report
08 Apr 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
PERCEPTIVE ADVISORS LLC 10%+ Owner $200,336,855 Mixed 18 Apr 2022
Richard Scott Struthers President & CEO, Director $58,407,741 -$1,001,513 -1.7% Mixed 16 Mar 2026
Ajay Madan Chief Development Officer $7,783,510 Mixed 28 Feb 2022
Stephen F. Betz Chief Scientific Officer $5,178,304 -$3,538,487 -41% Filing P/S 16 Mar 2026
Jeff E. Knight Chief Dev. & Operating Officer $4,222,088 -$3,785,448 -47% Filing P/S 08 Apr 2026
Wendall Wierenga Director $3,869,984 Mixed 11 Jun 2025
Tobin Schilke Chief Financial Officer $3,099,060 -$266,305 -7.9% Filing P/S 03 Mar 2026
Dana Pizzuti Chief Med and Dev Officer $3,009,001 -$1,910,299 -39% Filing P/S 01 Dec 2025
Isabel Kalofonos Chief Commercial Officer $1,939,905 -$137,500 -6.6% Mixed 23 Feb 2026
Marc Wilson Cfo $1,671,244 Mixed 31 Dec 2024
Alan Seth Krasner Chief Medical Officer $1,626,857 Mixed 17 Oct 2023
James Hassard Chief Commercial Officer $1,289,737 Filing P/S 05 Jul 2024
Matthew K. Fust Director $1,021,911 -$716,000 -41% Filing P/S 26 Sep 2025
Coelho Rogerio Vivaldi Director $599,351 -$180,761 -23% Filing P/S 12 Mar 2026
Camille L. Bedrosian Director $543,116 Mixed 11 Jun 2025
Weston Nichols Director $543,116 Mixed 11 Jun 2025
Caren Deardorf Director $543,116 Mixed 11 Jun 2025
Stephanie Okey Director $527,611 -$119,010 -18% Filing P/S 03 Mar 2026

Recent insider transactions for Crinetics Pharmaceuticals, Inc.

Showing up to 300 most recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % Reported value Reported price Shares Shares owned Date Ownership
Jeff E. Knight CRNX Common Stock Sale -44.7% $3,415,036 $40.10 -85,163 105,289 08 Apr 2026 Direct
Jeff E. Knight CRNX Common Stock Options Exercise 70% 78,434 190,452 08 Apr 2026 Direct
Jeff E. Knight CRNX Stock Option (Right to Buy) Options Exercise -88.1% -78,434 10,589 08 Apr 2026 Direct
Jeff E. Knight CRNX Common Stock Sale -8.13% $370,411 $37.37 -9,911 112,018 16 Mar 2026 Direct
Stephen F. Betz CRNX Common Stock Sale -7.18% $396,610 $37.37 -10,612 137,101 16 Mar 2026 Direct
Richard Scott Struthers CRNX Common Stock Sale -5.15% $821,513 $37.37 -21,981 404,778 16 Mar 2026 Direct
Coelho Rogerio Vivaldi CRNX Common Stock Sale -23.5% $180,761 $36.15 -5,000 16,300 12 Mar 2026 Direct
Stephanie Okey CRNX Common Stock Sale -18.4% $119,010 $39.67 -3,000 13,300 03 Mar 2026 Direct
Tobin Schilke CRNX Common Stock Sale -7.91% $266,305 $39.67 -6,713 78,121 03 Mar 2026 Direct
Richard Scott Struthers CRNX Common Stock Award 17% 62,000 426,759 23 Feb 2026 Direct
Richard Scott Struthers CRNX Stock Option (Right to Buy) Award 228,000 228,000 23 Feb 2026 Direct
Tobin Schilke CRNX Common Stock Award 60.6% 32,000 84,834 23 Feb 2026 Direct
Tobin Schilke CRNX Stock Option (Right to Buy) Award 50,000 50,000 23 Feb 2026 Direct
Jeff E. Knight CRNX Common Stock Award 38.7% 34,000 121,929 23 Feb 2026 Direct
Jeff E. Knight CRNX Stock Option (Right to Buy) Award 55,000 55,000 23 Feb 2026 Direct
Stephen F. Betz CRNX Common Stock Award 25.5% 30,000 147,713 23 Feb 2026 Direct
Stephen F. Betz CRNX Stock Option (Right to Buy) Award 47,000 47,000 23 Feb 2026 Direct
Isabel Kalofonos CRNX Common Stock Award 4076.7% 34,000 34,834 23 Feb 2026 Direct
Isabel Kalofonos CRNX Stock Option (Right to Buy) Award 55,000 55,000 23 Feb 2026 Direct
Isabel Kalofonos CRNX Common Stock Sale -75% $137,500 $55.00 -2,500 834 05 Jan 2026 Direct
Isabel Kalofonos CRNX Common Stock Options Exercise 299.8% 2,500 3,334 05 Jan 2026 Direct
Isabel Kalofonos CRNX Stock Option (Right to Buy) Options Exercise -2.5% -2,500 97,500 05 Jan 2026 Direct
Stephen F. Betz CRNX Common Stock Options Exercise 18% 18,000 117,713 26 Dec 2025 Direct
Stephen F. Betz CRNX Stock Option (Right to Buy) Options Exercise -16.6% -18,000 90,514 26 Dec 2025 Direct
Richard Scott Struthers CRNX Common Stock Options Exercise 14% 44,742 364,759 18 Dec 2025 Direct
Richard Scott Struthers CRNX Stock Option (Right to Buy) Options Exercise -100% -44,742 0 18 Dec 2025 Direct
Dana Pizzuti CRNX Common Stock Sale -6.96% $225,100 $45.02 -5,000 66,837 01 Dec 2025 Direct
Dana Pizzuti CRNX Common Stock Options Exercise 7.48% 5,000 71,837 01 Dec 2025 Direct
Dana Pizzuti CRNX Stock Option (Right to Buy) Options Exercise -6.75% -5,000 69,042 01 Dec 2025 Direct
Dana Pizzuti CRNX Common Stock Sale -7.02% $213,312 $42.66 -5,000 66,270 03 Nov 2025 Direct
Dana Pizzuti CRNX Common Stock Options Exercise 7.54% 5,000 71,270 03 Nov 2025 Direct
Dana Pizzuti CRNX Stock Option (Right to Buy) Options Exercise -6.33% -5,000 74,042 03 Nov 2025 Direct
Dana Pizzuti CRNX Common Stock Sale -7.02% $209,050 $41.81 -5,000 66,270 01 Oct 2025 Direct
Dana Pizzuti CRNX Common Stock Options Exercise 7.54% 5,000 71,270 01 Oct 2025 Direct
Dana Pizzuti CRNX Stock Option (Right to Buy) Options Exercise -5.95% -5,000 79,042 01 Oct 2025 Direct
Richard Scott Struthers CRNX Common Stock Sale -3.64% $180,000 $45.00 -4,000 106,000 26 Sep 2025 By Family Trust 2
Matthew K. Fust CRNX Common Stock Sale -41.2% $716,000 $44.75 -16,000 22,836 26 Sep 2025 Direct
Matthew K. Fust CRNX Common Stock Options Exercise 34.7% 10,000 38,836 26 Sep 2025 Direct
Matthew K. Fust CRNX Stock Option (Right to Buy) Options Exercise -82.7% -10,000 2,092 26 Sep 2025 Direct
Dana Pizzuti CRNX Common Stock Sale -4.94% $160,500 $32.10 -5,000 96,270 02 Sep 2025 Direct
Dana Pizzuti CRNX Common Stock Options Exercise 5.19% 5,000 101,270 02 Sep 2025 Direct
Dana Pizzuti CRNX Stock Option (Right to Buy) Options Exercise -5.62% -5,000 84,042 02 Sep 2025 Direct
Dana Pizzuti CRNX Common Stock Sale -31.2% $912,900 $30.43 -30,000 66,270 22 Aug 2025 Direct
Dana Pizzuti CRNX Common Stock Options Exercise 45.3% 30,000 96,270 22 Aug 2025 Direct
Dana Pizzuti CRNX Stock Option (Right to Buy) Options Exercise -25.2% -30,000 89,042 22 Aug 2025 Direct
Dana Pizzuti CRNX Common Stock Sale -8.92% $189,437 $29.18 -6,492 66,270 20 Aug 2025 Direct
Stephen F. Betz CRNX Common Stock Sale -49.4% $3,141,877 $32.23 -97,483 99,713 12 Jun 2025 Direct
Stephen F. Betz CRNX Common Stock Options Exercise 80.9% 88,170 197,196 12 Jun 2025 Direct
Stephen F. Betz CRNX Stock Option (Right to Buy) Options Exercise -60.2% -88,170 58,198 12 Jun 2025 Direct
Caren Deardorf CRNX Common Stock Award 73.4% 6,900 16,300 11 Jun 2025 Direct
* indicates a reported price that failed the local validity check.
We use cookies and similar technologies to provide certain features, enhance the user experience and, if you allow them, measure engagement and deliver advertising. Analytics and marketing storage stay off until you grant consent. By clicking on "Agree and continue", you declare your consent to the use of the selected optional cookies. Manage preferences to update or revoke optional consent for future visits. For more information, see our Privacy Policy .