Comparable stake leader
SABBY MANAGEMENT, LLC
SEC ownership of Lyra Therapeutics, Inc.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001327273.
Disclosed value leader
NBVM GP, LLC
Comparable rows
5/19
Latest evidence
14 May 2026
- Public ticker
- LYRA on OTC
- Parsed ownership sources
-
13D/G and 3/4/5
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
- Largest SEC-reported holder
-
SABBY MANAGEMENT, LLC
Ranking: Comparable ownership first, then disclosed value
- Comparable ownership rows
-
5 of 19
Meaning: Rows with safely comparable ownership %
- Latest 13D/G holder
-
SABBY MANAGEMENT, LLC
Source: Latest parsed Schedule 13D/G stake
- Latest parsed ownership date
-
14 May 2026
Freshness: Most recent filing date in this holder set
- Issuer CIK
- 0001327273
- Issuer location
- Watertown, MA
Ownership snapshot
CIK-linked ownership evidence from parsed SEC filings.
3 signals
Issuer
Names, identifiers, and filing context for this profile.
2 identity fields
Ownership snapshot
Top shareholders of Lyra Therapeutics, Inc. (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
SABBY MANAGEMENT, LLC
Disclosed value leader
NBVM GP, LLC
Comparable rows
5/19
Latest evidence
14 May 2026
13D/G
3/4/5
Lead comparable stake: 9.9%
14 rows are not safely comparable across share classes.
13D/G row: SABBY MANAGEMENT, LLC
Showing 1-8 of 19 holder rows.
Quick read
SABBY MANAGEMENT, LLC leads the comparable SEC ownership view at 9.9%.
5 of 19 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens SABBY MANAGEMENT, LLC's linked filing trail.
Comparable ownership
Top 5
SABBY MANAGEMENT, LLC
9.9%
Nantahala Capital Management, LLC
1.1%
Maria Palasis
62%
Jason Cavalier
29%
PERCEPTIVE ADVISORS LLC
0.79%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-8 of 19 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| SABBY MANAGEMENT, LLC |
13D/G
|
9.9%
|
$628,817
175,158 shares
|
$0 | 31 Dec 2025 |
| Nantahala Capital Management, LLC |
13D/G
|
1.1%
|
$84,253
702,106 shares
|
$0 | 30 Sep 2024 |
| Maria Palasis |
3/4/5
Principal Executive Officer, Director
|
62%
|
$3,371,668
1,094,733 shares
|
-$5,726 | 01 Apr 2026 |
| Jason Cavalier |
3/4/5
Principal Financial Officer
|
29%
|
$1,595,018
517,880 shares
|
-$2,587 | 01 Apr 2026 |
| PERCEPTIVE ADVISORS LLC |
3/4/5
10%+ Owner
|
0.79%
|
$54,702
14,026 shares
|
-$526,734 | 11 Nov 2025 |
| NBVM GP, LLC |
3/4/5
10%+ Owner
|
—
mixed-class rows
|
$7,473,948
3,123,551 shares
mixed-class rows
|
— | 31 May 2023 |
| Edward T. Anderson |
3/4/5
Director, 10%+ Owner
|
—
class O/S missing
|
—
20,000 shares
|
— | 30 Jun 2023 |
| Harlan Waksal |
3/4/5
Executive Chair, Director
|
—
class O/S missing
|
$1,591,460
536,966 shares
|
— | 09 Dec 2024 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider trading overview
Net insider flow leans to selling over the last 12 months. Net value: -$535,047.
Buys
$0
Insiders: 0
Sells
$535,047
Insiders: 3
Net
-$535,047
Shares: -118,736
Window
Last 12 months
4 rolling buckets
Buy value
Sell value
Shares: 0
Shares: 118,736
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 0 | $0 | $0 | $0 |
| 3-6 | 0 | 0 | $0 | $0 | $0 |
| 6-9 | 0 | 2,471 | $0 | $8,312 | -$8,312 |
| 9-12 | 0 | 116,265 | $0 | $526,734 | -$526,734 |
Reporting owners
Insider holders from Forms 3/4/5
Showing 1-17 of 17 reporting-owner rows connected to Lyra Therapeutics, Inc.. Open a relationship link for the CIK-to-CIK filing trail.
Rows
17
Largest Forms 3/4/5 holder
NBVM GP, LLC
Net 12M change
-$535,047
Latest report
14 May 2026
Recent insider transactions for Lyra Therapeutics, Inc.
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| W. Bradford Smith | LYRA | Common Stock | Disposed to Issuer | -100% | -640 | 0 | 14 May 2026 | Direct | ||
| Ph.D. Maria Palasis | LYRA | Common Stock | Disposed to Issuer | -0.18% | -2,000 | 1,094,733 | 01 Apr 2026 | Direct | ||
| Jason Cavalier | LYRA | Common Stock | Disposed to Issuer | -0.13% | -667 | 517,880 | 01 Apr 2026 | Direct | ||
| Jason Cavalier | LYRA | Common Stock | Sale | -0.15% | $2,587 | $3.36 | -769 | 518,547 | 06 Jan 2026 | Direct |
| Ph.D. Maria Palasis | LYRA | Common Stock | Sale | -0.15% | $5,726 | $3.36 | -1,702 | 1,096,733 | 06 Jan 2026 | Direct |
| Perceptive Advisors Llc | LYRA | Common Stock | Sale | -69.4% | $124,062 | $3.90 | -31,810 | 14,026 | 13 Nov 2025 | See Footnotes |
| Perceptive Advisors Llc | LYRA | Common Stock | Sale | -33.7% | $35,499 | $4.06 | -8,745 | 17,239 | 12 Nov 2025 | See Footnotes |
| Perceptive Advisors Llc | LYRA | Common Stock | Sale | -22.7% | $22,954 | $4.31 | -5,320 | 18,122 | 11 Nov 2025 | See Footnotes |
| Perceptive Advisors Llc | LYRA | Common Stock | Sale | -49.8% | $83,995 | $4.54 | -18,502 | 18,659 | 10 Nov 2025 | See Footnotes |
| Perceptive Advisors Llc | LYRA | Common Stock | Sale | -49% | $93,695 | $4.75 | -19,739 | 20,528 | 07 Nov 2025 | See Footnotes |
| Perceptive Advisors Llc | LYRA | Common Stock | Sale | -58.8% | $166,529 | $5.18 | -32,149 | 22,521 | 06 Nov 2025 | See Footnotes |
* marks a reported price that did not pass the local price check.