Comparable stake leader
Validae Health, L.P.
SEC ownership of Metsera, Inc.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0002040807.
Disclosed value leader
Validae Health, L.P.
Comparable rows
3/14
Latest evidence
31 Dec 2025
- Parsed ownership sources
- 13D/G and 3/4/5
- Largest SEC-reported holder
- Validae Health, L.P.
- Latest 13D/G holder
- Validae Health, L.P.
- Latest parsed ownership date
- 31 Dec 2025
- Issuer CIK
- 0002040807
- Issuer location
- New York, NY
Ownership snapshot
CIK-linked ownership evidence from parsed SEC filings.
2 signals
Issuer
Names, identifiers, and filing context for this profile.
2 identity fields
Ownership snapshot
Top shareholders of Metsera, Inc. (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
Validae Health, L.P.
Disclosed value leader
Validae Health, L.P.
Comparable rows
3/14
Latest evidence
31 Dec 2025
13D/G
3/4/5
Lead comparable stake: 12%
11 rows are not safely comparable across share classes.
13D/G row: Validae Health, L.P.
Showing 1-8 of 14 holder rows.
Quick read
Validae Health, L.P. leads the comparable SEC ownership view at 12%.
3 of 14 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens Validae Health, L.P.'s linked filing trail.
Comparable ownership
Top 3
Validae Health, L.P.
12%
VANGUARD GROUP INC
5.5%
JANUS HENDERSON GROUP PLC
3.1%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-8 of 14 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| Validae Health, L.P. |
13D/G
Christopher Whitten Bernard
|
12%
|
$346,544,669
13,136,644 shares
|
$0 | 31 Mar 2025 |
| VANGUARD GROUP INC |
13D/G
The Vanguard Group
|
5.5%
|
$304,823,049
5,824,993 shares
|
$0 | 30 Sep 2025 |
| JANUS HENDERSON GROUP PLC |
13D/G
|
3.1%
|
$228,620,854
3,242,849 shares
|
-$148,748,091 | 31 Dec 2025 |
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. |
3/4/5
10%+ Owner
|
—
class O/S missing
|
—
1,857,699 shares
|
— | 30 Jan 2025 |
| Jon P. Stonehouse |
3/4/5
Director
|
—
mixed-class rows
|
$945,531
2,688 shares
mixed-class rows
|
— | 13 Nov 2025 |
| Christopher Visioli |
3/4/5
CHIEF FINANCIAL OFFICER
|
—
class O/S missing
|
—
21,250 shares
|
— | 13 Nov 2025 |
| Christopher Witten Bernard |
3/4/5
PRESIDENT AND CHIEF EXECUTIVE OFFICER, Director
|
—
class O/S missing
|
—
21,250 shares
|
— | 13 Nov 2025 |
| Brian Hubbard |
3/4/5
CHIEF SCIENTIFIC OFFICER
|
—
class O/S missing
|
—
17,000 shares
|
— | 13 Nov 2025 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider trading overview
Net insider flow leans to selling over the last 12 months. Net value: -$11,817.
Buys
$0
Insiders: 0
Sells
$11,817
Insiders: 1
Net
-$11,817
Shares: -193
Window
Last 12 months
4 rolling buckets
Buy value
Sell value
Shares: 0
Shares: 193
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 0 | $0 | $0 | $0 |
| 3-6 | 0 | 0 | $0 | $0 | $0 |
| 6-9 | 0 | 193 | $0 | $11,817 | -$11,817 |
| 9-12 | 0 | 0 | $0 | $0 | $0 |
Reporting owners
Insider holders from Forms 3/4/5
Showing 1-15 of 15 reporting-owner rows connected to Metsera, Inc.. Open a relationship link for the CIK-to-CIK filing trail.
Rows
15
Largest Forms 3/4/5 holder
Jon P. Stonehouse
Net 12M change
-$11,817
Latest report
13 Nov 2025
Recent insider transactions for Metsera, Inc.
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Fmr Llc | MTSR | Common Stock | Other | -100% | -2,230,450 | 0 | 13 Nov 2025 | Shares held by persons and entities whose shares are subject to reporting by the undersigned. | ||
| Fmr Llc | MTSR | Common Stock | Other | -100% | -3,010 | 0 | 13 Nov 2025 | F-Prime Inc. | ||
| ARCH Venture Partners XII, LLC | MTSR | Common Stock | Disposed to Issuer | -100% | -26,816,808 | 0 | 13 Nov 2025 | See Footnote | ||
| Steven Marso | MTSR | Common Stock | Disposed to Issuer | -100% | -17,000 | 0 | 13 Nov 2025 | Direct | ||
| Steven Marso | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -971,164 | 0 | 13 Nov 2025 | Direct | ||
| Steven Marso | MTSR | Restricted Stock Unit | Award | 17,000 | 17,000 | 13 Nov 2025 | Direct | |||
| Population Health Partners GP, LLC | MTSR | Common Stock | Disposed to Issuer | -100% | -12,639,787 | 0 | 13 Nov 2025 | By Population Health Partners, L.P. | ||
| Population Health Partners GP, LLC | MTSR | Common Stock | Disposed to Issuer | -100% | -127,675 | 0 | 13 Nov 2025 | Direct | ||
| Brian Hubbard | MTSR | Common Stock | Disposed to Issuer | -100% | -17,000 | 0 | 13 Nov 2025 | Direct | ||
| Brian Hubbard | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -545,581 | 0 | 13 Nov 2025 | Direct | ||
| Brian Hubbard | MTSR | Restricted Stock Unit | Award | 17,000 | 17,000 | 13 Nov 2025 | Direct | |||
| Christopher Witten Bernard | MTSR | Common Stock | Disposed to Issuer | -100% | -12,767,462 | 0 | 13 Nov 2025 | Held by Population Health Partners, L.P. and Population Health GP LLC | ||
| Christopher Witten Bernard | MTSR | Common Stock | Disposed to Issuer | -100% | -21,250 | 0 | 13 Nov 2025 | Direct | ||
| Christopher Witten Bernard | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -2,051,078 | 0 | 13 Nov 2025 | Direct | ||
| Christopher Witten Bernard | MTSR | Restricted Stock Unit | Award | 21,250 | 21,250 | 13 Nov 2025 | Direct | |||
| Joshua Pinto | MTSR | Common Stock | Disposed to Issuer | -100% | -2,688 | 0 | 13 Nov 2025 | Direct | ||
| Joshua Pinto | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -148,953 | 0 | 13 Nov 2025 | By LLC | ||
| Joshua Pinto | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -16,125 | 0 | 13 Nov 2025 | Direct | ||
| Joshua Pinto | MTSR | Restricted Stock Unit | Award | 2,688 | 2,688 | 13 Nov 2025 | Direct | |||
| Christopher Visioli | MTSR | Common Stock | Disposed to Issuer | -100% | -21,250 | 0 | 13 Nov 2025 | Direct | ||
| Christopher Visioli | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -745,814 | 0 | 13 Nov 2025 | Direct | ||
| Christopher Visioli | MTSR | Restricted Stock Unit | Award | 21,250 | 21,250 | 13 Nov 2025 | Direct | |||
| Matthew Lang | MTSR | Common Stock | Disposed to Issuer | -100% | -12,500 | 0 | 13 Nov 2025 | Direct | ||
| Matthew Lang | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -371,875 | 0 | 13 Nov 2025 | Direct | ||
| Matthew Lang | MTSR | Restricted Stock Unit | Award | 12,500 | 12,500 | 13 Nov 2025 | Direct | |||
| Kristina M. Burow. | MTSR | Common Stock | Disposed to Issuer | -100% | -51,411,394 | 0 | 13 Nov 2025 | See footnote | ||
| Kristina M. Burow. | MTSR | Common Stock | Disposed to Issuer | -100% | -2,688 | 0 | 13 Nov 2025 | Direct | ||
| Kristina M. Burow. | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -165,078 | 0 | 13 Nov 2025 | Direct | ||
| Kristina M. Burow. | MTSR | Restricted Stock Unit | Award | 2,688 | 2,688 | 13 Nov 2025 | Direct | |||
| Jon P. Stonehouse | MTSR | Common Stock | Disposed to Issuer | -100% | -2,688 | 0 | 13 Nov 2025 | Direct | ||
| Jon P. Stonehouse | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -47,730 | 0 | 13 Nov 2025 | Direct | ||
| Jon P. Stonehouse | MTSR | Restricted Stock Unit | Award | 2,688 | 2,688 | 13 Nov 2025 | Direct | |||
| Clive Meanwell | MTSR | Common Stock | Disposed to Issuer | -100% | -12,767,462 | 0 | 13 Nov 2025 | Held by Population Health Partners, L.P. and Population Health GP LLC | ||
| Clive Meanwell | MTSR | Common Stock | Disposed to Issuer | -100% | -5,375 | 0 | 13 Nov 2025 | Direct | ||
| Clive Meanwell | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -330,157 | 0 | 13 Nov 2025 | Direct | ||
| Clive Meanwell | MTSR | Restricted Stock Unit | Award | 5,375 | 5,375 | 13 Nov 2025 | Direct | |||
| Paul L. Berns | MTSR | Common Stock | Disposed to Issuer | -100% | -15,837,362 | 0 | 13 Nov 2025 | See footnote | ||
| Paul L. Berns | MTSR | Common Stock | Disposed to Issuer | -100% | -961,590 | 0 | 13 Nov 2025 | Direct | ||
| Paul L. Berns | MTSR | Stock Option (right to buy) | Disposed to Issuer | -100% | -247,618 | 0 | 13 Nov 2025 | Direct | ||
| Paul L. Berns | MTSR | Restricted Stock Unit | Award | 4,031 | 4,031 | 13 Nov 2025 | Direct | |||
| Validae Health, L.P. | MTSR | Common Stock | Other | -100% | -12,767,462 | 0 | 11 Nov 2025 | Direct | ||
| Fmr Llc | MTSR | Common Stock | Gift | -27.8% | -860,722 | 2,230,450 | 10 Nov 2025 | Shares held by persons and entities whose shares are subject to reporting by the undersigned. | ||
| Fmr Llc | MTSR | Common Stock | Other | 552.4% | 2,617,340 | 3,091,172 | 03 Nov 2025 | Shares held by persons and entities whose shares are subject to reporting by the undersigned. | ||
| Fmr Llc | MTSR | Common Stock | Other | -100% | -2,356,081 | 0 | 03 Nov 2025 | Impresa Fund IV LLC | ||
| Fmr Llc | MTSR | Common Stock | Sale | -0.01% | $11,817 | $61.23 | -193 | 2,356,081 | 03 Nov 2025 | Impresa Fund IV LLC |
| Fmr Llc | MTSR | Common Stock | Other | 2,356,274 | 2,356,274 | 03 Nov 2025 | Impresa Fund IV LLC | |||
| Fmr Llc | MTSR | Common Stock | Other | 236.3% | 2,115 | 3,010 | 03 Nov 2025 | F-Prime Inc. | ||
| Fmr Llc | MTSR | Common Stock | Other | -100% | -47,843 | 0 | 03 Nov 2025 | F-Prime Capital Partners Life Sciences Advisors Fund VIII LP | ||
| Fmr Llc | MTSR | Common Stock | Other | 47,843 | 47,843 | 03 Nov 2025 | F-Prime Capital Partners Life Sciences Advisors Fund VIII LP | |||
| Fmr Llc | MTSR | Common Stock | Other | -100% | -3,189,540 | 0 | 03 Nov 2025 | F-Prime Capital Partners Life Sciences Fund VIII LP |
* marks a reported price that did not pass the local price check.