Insider Trading & Ownership of FMR LLC

Location
Boston, MA
Summary
The estimated value of insider holdings of FMR LLC is at least $588M dollars as of 10 Dec 2025. FMR LLC is the Other* of Flywire Corp and owns shares of Flywire Corp (FLYW) stock worth about $135M. FMR LLC is the Other* of Prime Medicine, Inc. and owns shares of Prime Medicine, Inc. (PRME) stock worth about $127M. FMR LLC is the Other* of Toast, Inc. and owns shares of Toast, Inc. (TOST) stock worth about $113M. FMR LLC is the Other* of Neumora Therapeutics, Inc. and owns shares of Neumora Therapeutics, Inc. (NMRA) stock worth about $67.4M. FMR LLC is the Other*, 10%+ Owner of Beam Therapeutics Inc. and owns shares of Beam Therapeutics Inc. (BEAM) stock worth about $48.1M. FMR LLC is the Other*, 10%+ Owner of Structure Therapeutics Inc. and owns shares of Structure Therapeutics Inc. (GPCR) stock worth about $43.6M. FMR LLC is the Other* of Bicara Therapeutics Inc. and owns shares of Bicara Therapeutics Inc. (BCAX) stock worth about $14.8M. FMR LLC is the Other* of Rallybio Corp and owns shares of Rallybio Corp (RLYB) stock worth about $13.9M. FMR LLC is the Other* of Caribou Biosciences, Inc. and owns shares of Caribou Biosciences, Inc. (CRBU) stock worth about $9.84M. FMR LLC is the Other*, 10%+ Owner of Sana Biotechnology, Inc. and owns shares of Sana Biotechnology, Inc. (SANA) stock worth about $7.49M. FMR LLC is the Other* of Verve Therapeutics, Inc. and owns shares of Verve Therapeutics, Inc. (VERV) stock worth about $5.71M. FMR LLC is the Other* of Xilio Therapeutics, Inc. and owns shares of Xilio Therapeutics, Inc. (XLO) stock worth about $1.58M. FMR LLC is the Other* of Fidelity Private Credit Fund and owns shares of Fidelity Private Credit Fund stock worth about $20.3K.
Signature
/s/ Stephanie J. Brown, Duly authorized under Powers of Attorney, by and on behalf of FMR LLC and its direct and indirect subsidiaries, and Abigail P. Johnson
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Ownership of FMR LLC

Symbol Company Relationship Holdings Value Past Year Net Change Change % Report Period
FLYW Flywire Corp Other* $135M 28 May 2021
PRME Prime Medicine, Inc. Other* $127M 24 Oct 2022
TOST Toast, Inc. Other* $113M 09 Nov 2021
NMRA Neumora Therapeutics, Inc. Other* $67.4M 19 Sep 2023
BEAM Beam Therapeutics Inc. Other*, 10%+ Owner $48.1M -$1M -2.05% 27 Oct 2025
GPCR Structure Therapeutics Inc. Other*, 10%+ Owner $43.6M -$2.61M -5.65% 08 Dec 2025
BCAX Bicara Therapeutics Inc. Other* $14.8M 16 Sep 2024
RLYB Rallybio Corp Other* $13.9M 02 Aug 2021
CRBU Caribou Biosciences, Inc. Other* $9.84M 27 Jul 2021
SANA Sana Biotechnology, Inc. Other*, 10%+ Owner $7.49M 08 Jan 2025
VERV Verve Therapeutics, Inc. Other* $5.71M 26 Jul 2022
XLO Xilio Therapeutics, Inc. Other* $1.58M 26 Oct 2021
NONE Fidelity Private Credit Fund Other* $20.3K 29 Jan 2024
MTSR Metsera, Inc. Other*, 10%+ Owner $0 -$11.8K -100% 13 Nov 2025
NONE Fidelity Multi-Strategy Credit Fund Other*, 10%+ Owner 19 May 2023
TSBX Turnstone Biologics Corp. Other* 09 Jan 2024

Insider Transactions Reported by FMR LLC:

Sym Company Class Transaction % Value $ * Price $ Shares Shares After Date Ownership
* An asterisk sign (*) next to the price indicates that the price is likely invalid.