SEC ownership of Tango Therapeutics, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001819133.

Comparable stake leader

FARALLON PARTNERS L L C/CA

Disclosed value leader

FARALLON CAPITAL MANAGEMENT, L.L.C.

Comparable rows

50/50

Latest evidence

22 Sep 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
50 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
FARALLON PARTNERS L L C/CA
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
22 Sep 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001819133
Issuer location
Boston, MA

Ownership snapshot

Top shareholders of Tango Therapeutics, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
FARALLON PARTNERS L L C/CA
Disclosed value leader
FARALLON CAPITAL MANAGEME...
Comparable rows
50/50
Latest evidence
22 Sep 2026
13D/G 13F 3/4/5 Lead comparable stake: 10% 13D/G row: FARALLON PARTNERS L L C/CA Showing 1-8 of 50 holder rows.

Quick read

FARALLON PARTNERS L L C/CA leads the comparable SEC ownership view at 10%.

50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens FARALLON PARTNERS L L C/CA's linked filing trail.
Comparable ownership Top 5
FARALLON PARTNERS L L C/CA 10%
FARALLON CAPITAL MANAGEMENT, L.L.C. 9.8%
RTW INVESTMENTS, LP 9.3%
Farallon Capital Partners, L.P. 7.8%
TCG Crossover GP II, LLC 7%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
FARALLON PARTNERS L L C/CA
13D/G
Dapice Joshua J.
10%
$119,266,365
13,461,215 shares
$0 31 Dec 2025
FARALLON CAPITAL MANAGEMENT, L.L.C.
13D/G 13F
Company
9.8%
$498,518,530
16,270,187 shares
$0 30 Jun 2026
RTW INVESTMENTS, LP
13F 13D/G
Company
9.3%
from 13D/G
$434,533,381
13,900,620 shares
— 30 Jun 2026
Farallon Capital Partners, L.P.
13D/G
Dapice Joshua J.
7.8%
$235,500,687
11,257,203 shares
+$10,464,247 31 Mar 2026
TCG Crossover GP II, LLC
13D/G
7%
$310,930,645
10,147,867 shares
-$44,424,017 30 Jun 2026
FMR LLC
13F 13D/G
Company
6.9%
from 13D/G
$385,540,161
12,333,339 shares
— 30 Jun 2026
BlackRock, Inc.
13F 13D/G
Company
6.3%
from 13D/G
$388,825,760
12,438,444 shares
— 30 Jun 2026
GOLDMAN SACHS GROUP INC
13F 13D/G
Company · THE GOLDMAN SACHS GROUP, INC.
6%
from 13D/G
$311,994,191
9,980,620 shares
— 30 Jun 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$11,874,587.

Buys
$0
Insiders: 0
Sells
$11,874,587
Insiders: 5
Net
-$11,874,587
Shares: -831,945
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 831,945
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 89,200 $0 $2,336,947 -$2,336,947
3-6 0 119,460 $0 $2,724,647 -$2,724,647
6-9 0 145,884 $0 $1,966,418 -$1,966,418
9-12 0 477,401 $0 $4,846,575 -$4,846,575

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-20 of 27 reporting-owner rows connected to Tango Therapeutics, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
27
Largest Forms 3/4/5 holder
Boxer Capital, LLC
Net 12M change
-$11,874,588
Latest report
22 Sep 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Boxer Capital, LLC Other* $139,494,711 Mixed 13 Oct 2023
Third Rock Ventures IV, L.P. 10%+ Owner $135,900,499 -$4,846,575 -3.4% Filing P/S 23 Oct 2025
BCTG Holdings, LLC 10%+ Owner $58,642,879 Mixed 10 Aug 2021
EcoR1 Capital, LLC 10%+ Owner $31,010,920 Filing P/S 06 Nov 2024
Barbara Weber Director, Executive Chair, Director $21,012,651 -$374,294 -1.8% Filing P/S 02 Feb 2026
Boxer Capital Management, LLC Other* $11,337,416 Filing P/S 06 Nov 2024
Malte Peters President & CEO, Director $3,256,050 Mixed 08 Jan 2026
Adam Crystal President, R&D $2,588,823 -$6,328,575 -71% Filing P/S 01 Sep 2026
Daniella Beckman Chief Financial Officer $2,376,896 -$126,531 -5.1% Filing P/S 02 Feb 2026
Third Rock Ventures VI, L.P. Director $1,629,392 Mixed 11 Aug 2023
Jessica Newcomb Principal Accounting Officer $1,488,181 -$198,613 -12% Filing P/S 22 Sep 2026
Alan Huang Chief Scientific Officer $1,406,264 Mixed 01 Mar 2023
MVA Investors, LLC Other* $944,323 Filing P/S 28 Jun 2024
Mace Rothenberg Director $868,180 Mixed 05 Jun 2026
Matthew Gall Chief Financial Officer $836,800 Mixed 01 May 2026
John B. Ketchum Director $521,682 Mixed 05 Jun 2026
Sung Lee Director $478,440 Mixed 05 Jun 2026
Lesley Ann Calhoun Director $345,180 Mixed 05 Jun 2026
Braslyn Ltd. 10%+ Owner $226,241 Mixed 10 Aug 2021
Douglas Barry General Counsel $208,697 Filing P/S 04 Feb 2025

Recent insider transactions for Tango Therapeutics, Inc.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Jessica Newcomb TNGX Common Stock Sale -12.2% $198,613 $24.22 -8,200 59,121 22 Sep 2026 Direct
Adam Crystal TNGX Common Stock Sale -18.9% $603,909 $22.37 -27,000 115,743 01 Sep 2026 Direct
Adam Crystal TNGX Common Stock Options Exercise 23.3% 27,000 142,743 01 Sep 2026 Direct
Adam Crystal TNGX Stock Option (Right to Buy) Options Exercise -9.41% -27,000 260,040 01 Sep 2026 Direct
Adam Crystal TNGX Common Stock Sale -18.9% $735,517 $27.24 -27,000 115,743 03 Aug 2026 Direct
Adam Crystal TNGX Common Stock Options Exercise 23.3% 27,000 142,743 03 Aug 2026 Direct
Adam Crystal TNGX Stock Option (Right to Buy) Options Exercise -8.6% -27,000 287,040 03 Aug 2026 Direct
Adam Crystal TNGX Common Stock Sale -18.9% $798,908 $29.59 -27,000 115,743 01 Jul 2026 Direct
Adam Crystal TNGX Common Stock Options Exercise 23.3% 27,000 142,743 01 Jul 2026 Direct
Adam Crystal TNGX Stock Option (Right to Buy) Options Exercise -7.92% -27,000 314,040 01 Jul 2026 Direct
Robert Azelby TNGX Common Stock Award 5,740 5,740 19 Jun 2026 Direct
Robert Azelby TNGX Stock Option (Right to Buy) Award 35,910 35,910 19 Jun 2026 Direct
John B. Ketchum TNGX Common Stock Award 19.1% 4,000 24,937 05 Jun 2026 Direct
John B. Ketchum TNGX Stock Option (Right to Buy) Award 25,000 25,000 05 Jun 2026 Direct
Lesley Ann Calhoun TNGX Common Stock Award 32% 4,000 16,500 05 Jun 2026 Direct
Lesley Ann Calhoun TNGX Stock Option (Right to Buy) Award 25,000 25,000 05 Jun 2026 Direct
Mace Rothenberg TNGX Common Stock Award 10.7% 4,000 41,500 05 Jun 2026 Direct
Mace Rothenberg TNGX Stock Option (Right to Buy) Award 25,000 25,000 05 Jun 2026 Direct
Sung Lee TNGX Common Stock Award 2.56% 570 22,870 05 Jun 2026 Direct
Sung Lee TNGX Stock Option (Right to Buy) Award 3,570 3,570 05 Jun 2026 Direct
Adam Crystal TNGX Common Stock Sale -18.9% $617,571 $22.87 -27,000 115,743 01 Jun 2026 Direct
Adam Crystal TNGX Common Stock Options Exercise 23.3% 27,000 142,743 01 Jun 2026 Direct
Adam Crystal TNGX Stock Option (Right to Buy) Options Exercise -7.34% -27,000 341,040 01 Jun 2026 Direct
Adam Crystal TNGX Common Stock Sale -18.9% $573,097 $21.23 -27,000 115,743 01 May 2026 Direct
Adam Crystal TNGX Common Stock Options Exercise 23.3% 27,000 142,743 01 May 2026 Direct
Adam Crystal TNGX Stock Option (Right to Buy) Options Exercise -6.83% -27,000 368,040 01 May 2026 Direct
Matthew Gall TNGX Common Stock Award 40,000 40,000 01 May 2026 Direct
Matthew Gall TNGX Stock Option (Right to Buy) Award 240,000 240,000 01 May 2026 Direct
Sung Lee TNGX Common Stock Award 123% 12,300 22,300 29 Apr 2026 Direct
Sung Lee TNGX Stock Option (Right to Buy) Award 5,200 5,200 29 Apr 2026 Direct
Adam Crystal TNGX Common Stock Sale -25.5% $961,500 $25.00 -38,460 112,622 15 Apr 2026 Direct
Adam Crystal TNGX Common Stock Options Exercise 34.2% 38,460 151,082 15 Apr 2026 Direct
Adam Crystal TNGX Stock Option (Right to Buy) Options Exercise -8.87% -38,460 395,040 15 Apr 2026 Direct
Adam Crystal TNGX Common Stock Sale -19.3% $572,478 $21.20 -27,000 112,622 01 Apr 2026 Direct
Adam Crystal TNGX Common Stock Options Exercise 24% 27,000 139,622 01 Apr 2026 Direct
Adam Crystal TNGX Stock Option (Right to Buy) Options Exercise -5.86% -27,000 433,500 01 Apr 2026 Direct
Adam Crystal TNGX Common Stock Sale -9.63% $241,320 $20.11 -12,000 112,622 25 Mar 2026 Direct
Adam Crystal TNGX Common Stock Options Exercise 10.7% 12,000 124,622 25 Mar 2026 Direct
Adam Crystal TNGX Stock Option (Right to Buy) Options Exercise -2.54% -12,000 460,500 25 Mar 2026 Direct
Adam Crystal TNGX Common Stock Sale -15.2% $303,765 $15.00 -20,251 112,622 05 Mar 2026 Direct
Adam Crystal TNGX Common Stock Sale -29% $694,208 $12.77 -54,345 132,873 25 Feb 2026 Direct
Adam Crystal TNGX Common Stock Sale -8.97% $226,300 $12.26 -18,452 187,218 03 Feb 2026 Direct
Barbara Weber TNGX Common Stock Sale -1.84% $374,294 $12.26 -30,519 1,629,254 03 Feb 2026 Direct
Daniella Beckman TNGX Common Stock Sale -5.3% $126,531 $12.26 -10,317 184,297 03 Feb 2026 Direct
Adam Crystal TNGX Common Stock Award 30% 47,460 205,670 02 Feb 2026 Direct
Adam Crystal TNGX Stock Option (Right to Buy) Award 284,760 284,760 02 Feb 2026 Direct
Barbara Weber TNGX Common Stock Award 2.31% 37,522 1,659,773 02 Feb 2026 Direct
Barbara Weber TNGX Stock Option (Right to Buy) Award 222,132 222,132 02 Feb 2026 Direct
Daniella Beckman TNGX Common Stock Award 29.5% 44,330 194,614 02 Feb 2026 Direct
Daniella Beckman TNGX Stock Option (Right to Buy) Award 265,980 265,980 02 Feb 2026 Direct
* marks a reported price that did not pass the local price check.
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