SEC ownership of Design Therapeutics, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001807120.

Comparable stake leader

SR One Capital Fund I Aggregator LP

Disclosed value leader

SR ONE CAPITAL MANAGEMENT, LP

Comparable rows

50/50

Latest evidence

30 Jun 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
50 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
SR One Capital Fund I Aggregator LP
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
30 Jun 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001807120
Issuer location
Carlsbad, CA

Ownership snapshot

Top shareholders of Design Therapeutics, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
SR One Capital Fund I Agg...
Disclosed value leader
SR ONE CAPITAL MANAGEMENT...
Comparable rows
50/50
Latest evidence
30 Jun 2026
13D/G 3/4/5 13F Lead comparable stake: 11% 13D/G row: SR One Capital Fund I Aggregator LP Showing 1-8 of 50 holder rows.

Quick read

SR One Capital Fund I Aggregator LP leads the comparable SEC ownership view at 11%.

50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens SR One Capital Fund I Aggregator LP's linked filing trail.
Comparable ownership Top 5
SR One Capital Fund I Aggregator LP 11%
Sirenia Capital Management LP 9.5%
Light Irrevocable Trust #1 dated ... 6.9%
Star Irrevocable Trust #1 dated A... 6.9%
Logos Global Management LP 4.4%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
SR One Capital Fund I Aggregator LP
13D/G 3/4/5
Simeon George · 10%+ Owner
11%
$62,048,106
6,607,892 shares
$0 09 Mar 2026
Sirenia Capital Management LP
13D/G
9.5%
$93,275,959
5,963,936 shares
$0 30 Jun 2026
Light Irrevocable Trust #1 dated April 22, 2019
13D/G
6.9%
$16,257,665
3,834,355 shares
$0 31 Dec 2024
Star Irrevocable Trust #1 dated April 22, 2019
13D/G
6.9%
$16,257,665
3,834,355 shares
$0 31 Dec 2024
Logos Global Management LP
13F 13D/G
Company · Arsani William
4.4%
from 13D/G
$43,410,000
3,000,000 shares
— 30 Jun 2026
Point72 Asset Management, L.P.
13D/G 13F
Company
3.8%
$37,011,325
2,366,453 shares
-$13,001,704 30 Jun 2026
SR ONE CAPITAL MANAGEMENT, LP
13F
Company
13F
10%
$94,438,108
6,526,476 shares
— 30 Jun 2026
BAKER BROS. ADVISORS LP
13F
Company
13F
4.3%
$38,756,882
2,678,430 shares
— 30 Jun 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Insider buy and sell flow is broadly balanced over the last 12 months. No Buy or Sell transactions have been reported since 06 Oct 2025.

Buys
$0
Insiders: 0
Sells
$0
Insiders: 0
Net
$0
Shares: 0
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 0
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 0 $0 $0 $0
6-9 0 0 $0 $0 $0
9-12 0 0 $0 $0 $0

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-19 of 19 reporting-owner rows connected to Design Therapeutics, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
19
Largest Forms 3/4/5 holder
Arsani William
Net 12M change
$0
Latest report
09 Jun 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Arsani William Director $19,188,750 Filing P/S 13 Aug 2025
SR One Capital Fund I Aggregator LP 10%+ Owner $15,317,639 Mixed 16 Dec 2022
Deepa Prasad Director $125,400 Filing P/S 10 Jun 2025
Dawn Giangiulio Principal Accounting Officer $17,603 Mixed 13 Aug 2021
Jae B. Kim Chief Medical Officer $11,162 Mixed 13 Mar 2024
Heather A. Berger Director Mixed 09 Jun 2026
Sean Jeffries Chief Operating Officer Mixed 02 Jan 2026
Julie Burgess Chief Accounting Officer Mixed 02 Jan 2026
Aseem Z. Ansari 10%+ Owner Mixed 01 Dec 2023
Joao Siffert MD President and CEO, Director Mixed 01 Feb 2023
Pratik Shah President, CEO and Chairperson, Director Mixed 02 Jan 2026
Simeon George Director, 10%+ Owner Mixed 09 Jun 2026
Justin D. Gover Director Mixed 09 Jun 2026
DUNHAM TRUST Co 10%+ Owner Mixed 01 Oct 2024
David Shapiro Director Mixed 09 Jun 2026
Rodney W. Lappe Director Mixed 09 Jun 2026
John P. Schmid Director Mixed 09 Jun 2026
Chris Storgard Chief Medical Officer Mixed 02 Jan 2026
Stella Xu Director Mixed 31 May 2023

Recent insider transactions for Design Therapeutics, Inc.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Simeon George DSGN Stock Option (right to buy) Award 30,000 30,000 09 Jun 2026 Direct
John P. Schmid DSGN Stock Option (right to buy) Award 30,000 30,000 09 Jun 2026 Direct
Rodney W. Lappe DSGN Stock Option (right to buy) Award 30,000 30,000 09 Jun 2026 Direct
Justin D. Gover DSGN Stock Option (right to buy) Award 30,000 30,000 09 Jun 2026 Direct
David Shapiro DSGN Stock Option (right to buy) Award 30,000 30,000 09 Jun 2026 Direct
Heather A. Berger DSGN Stock Option (right to buy) Award 30,000 30,000 09 Jun 2026 Direct
David Shapiro DSGN Stock option (right to buy) Award 67,500 60,000 31 Mar 2026 Direct
Chris Storgard DSGN Stock option (right to buy) Award 250,000 250,000 02 Jan 2026 Direct
Sean Jeffries DSGN Stock option (right to buy) Award 375,000 375,000 02 Jan 2026 Direct
Julie Burgess DSGN Stock option (right to buy) Award 150,000 150,000 02 Jan 2026 Direct
Justin D. Gover DSGN Stock option (right to buy) Award 45,000 45,000 02 Jan 2026 Direct
Pratik Shah DSGN Stock option (right to buy) Award 750,000 750,000 02 Jan 2026 Direct
Pratik Shah DSGN Stock option (right to buy) Award 1,050,000 525,000 09 Dec 2025 Direct
* marks a reported price that did not pass the local price check.
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