Comparable stake leader
JANUS HENDERSON GROUP PLC
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001746466.
Comparable stake leader
JANUS HENDERSON GROUP PLC
Disclosed value leader
ADAR1 Capital Management, LLC
Comparable rows
50/50
Latest evidence
31 Mar 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC |
13F
13D/G
Company
|
10%
from 13D/G
|
$12,956,669
6,494,571 shares
|
— | 31 Mar 2026 |
| Adage Capital Management, L.P. |
13D/G
|
10%
|
$8,596,850
6,012,624 shares
|
$0 | 30 Sep 2025 |
| ADAR1 Capital Management, LLC |
13D/G
13F
Company
|
9.9%
|
$13,735,808
6,603,754 shares
|
+$850,454 | 31 Mar 2026 |
| RA CAPITAL MANAGEMENT, L.P. |
13D/G
13F
Company
|
9.9%
|
$11,275,564
6,480,209 shares
|
$0 | 13 Mar 2026 |
| Decheng Capital Management IV (Cayman), LLC |
13D/G
Xiangmin Cui
|
8.9%
|
$10,950,070
5,733,021 shares
|
$0 | 31 Mar 2026 |
| Woodline Partners LP |
13F
13D/G
Company
|
5.9%
from 13D/G
|
$7,001,802
3,500,901 shares
|
— | 31 Mar 2026 |
| Aberdeen Group plc |
13F
13D/G
Company
|
5.3%
from 13D/G
|
$6,705,674
3,352,837 shares
|
— | 31 Mar 2026 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
Company
|
8%
|
$10,658,832
5,329,416 shares
|
— | 31 Mar 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to selling over the last 12 months. Net value: -$2,430,494.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 406,392 | $0 | $1,225,526 | -$1,225,526 |
| 3-6 | 0 | 494,001 | $0 | $999,786 | -$999,786 |
| 6-9 | 0 | 143,802 | $0 | $205,182 | -$205,182 |
| 9-12 | 0 | 0 | $0 | $0 | $0 |
Reporting owners
Showing 1-14 of 14 reporting-owner rows connected to Equillium, Inc.. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Stephen Connelly | President and CSO | $2,240,429 | -$723,830 | -24% | Filing P/S | 04 Jun 2026 |
| Christine Zedelmayer | Sr. Vice President and COO | $183,402 | -$1,506,487 | -89% | Filing P/S | 05 Jun 2026 |
| Jason A. Keyes | Chief Financial Officer | $82,311 | Mixed | 14 Feb 2025 | ||
| Joel Rothman | Chief Development Officer | $33,727 | Mixed | 02 Jan 2024 | ||
| Penny Tom | Principal Accounting Officer | $0 | -$200,178 | -100% | Mixed | 28 May 2026 |
| Bruce D. Steel | Chief Executive Officer, Director, 10%+ Owner | Mixed | 07 Jan 2026 | |||
| Bala S. Manian | Director | Mixed | 21 May 2025 | |||
| Charles Douglas McDermott | Director | Mixed | 28 May 2026 | |||
| Daniel Bradbury | CHAIRMAN, Director | Mixed | 28 May 2026 | |||
| Mark Pruzanski | Director | Mixed | 28 May 2026 | |||
| Martha J. Demski | Director | Mixed | 28 May 2026 | |||
| Barbara Troupin | Director | Mixed | 28 May 2026 | |||
| Ph.D. Yu Xu | Director | Mixed | 22 May 2024 | |||
| Peter Colabuono | Director | Mixed | 21 May 2025 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Christine Zedelmayer | EQ | Common Stock | Sale | -18.9% | $42,737 | $2.93 | -14,584 | 62,586 | 05 Jun 2026 | Direct |
| Christine Zedelmayer | EQ | Common Stock | Options Exercise | 23.3% | 14,584 | 77,170 | 05 Jun 2026 | Direct | ||
| Christine Zedelmayer | EQ | Employee Stock Option (right to buy) | Options Exercise | -36.4% | -14,584 | 25,521 | 05 Jun 2026 | Direct | ||
| Stephen Connelly | EQ | Common Stock | Sale | -3.91% | $91,070 | $2.94 | -30,975 | 762,025 | 05 Jun 2026 | Direct |
| Stephen Connelly | EQ | Common Stock | Sale | -20.1% | $632,760 | $3.16 | -200,000 | 793,000 | 04 Jun 2026 | Direct |
| Penny Tom | EQ | Common Stock | Sale | -100% | $191,750 | $2.95 | -65,000 | 0 | 28 May 2026 | Direct |
| Penny Tom | EQ | Common Stock | Options Exercise | 65,000 | 65,000 | 28 May 2026 | Direct | |||
| Penny Tom | EQ | Employee Stock Option (right to buy) | Options Exercise | -100% | -65,000 | 0 | 28 May 2026 | Direct | ||
| Martha J. Demski | EQ | Director Stock Option (right to buy) | Award | 70,000 | 70,000 | 28 May 2026 | Direct | |||
| Mark Pruzanski | EQ | Director Stock Option (right to buy) | Award | 70,000 | 70,000 | 28 May 2026 | Direct | |||
| Daniel Bradbury | EQ | Director stock option (right to buy) | Award | 70,000 | 70,000 | 28 May 2026 | Direct | |||
| Christine Zedelmayer | EQ | Common Stock | Sale | -57.9% | $240,693 | $2.80 | -86,012 | 62,586 | 28 May 2026 | Direct |
| Christine Zedelmayer | EQ | Common Stock | Options Exercise | 265.6% | 86,012 | 118,390 | 28 May 2026 | Direct | ||
| Christine Zedelmayer | EQ | Employee Stock Option (right to buy) | Options Exercise | -100% | -86,012 | 0 | 28 May 2026 | Direct | ||
| Charles Douglas McDermott | EQ | Director Stock Option (right to buy) | Award | 70,000 | 70,000 | 28 May 2026 | Direct | |||
| Barbara Troupin | EQ | Director Stock Option (right to buy) | Award | 70,000 | 70,000 | 28 May 2026 | Direct | |||
| Christine Zedelmayer | EQ | Common Stock | Sale | -13.6% | $26,517 | $2.70 | -9,821 | 62,586 | 27 May 2026 | Direct |
| Christine Zedelmayer | EQ | Common Stock | Options Exercise | 15.7% | 9,821 | 72,407 | 27 May 2026 | Direct | ||
| Christine Zedelmayer | EQ | Employee Stock Option (right to buy) | Options Exercise | -5.61% | -9,821 | 165,179 | 27 May 2026 | Direct | ||
| Christine Zedelmayer | EQ | Common Stock | Sale | -65.8% | $300,816 | $2.50 | -120,312 | 62,586 | 13 Mar 2026 | Direct |
| Christine Zedelmayer | EQ | Common Stock | Options Exercise | 192.2% | 120,312 | 182,898 | 13 Mar 2026 | Direct | ||
| Christine Zedelmayer | EQ | Employee Stock Option (right to buy) | Options Exercise | -68.8% | -120,312 | 54,688 | 13 Mar 2026 | Direct | ||
| Christine Zedelmayer | EQ | Common Stock | Sale | -74.3% | $362,438 | $2.00 | -181,219 | 62,586 | 09 Mar 2026 | Direct |
| Christine Zedelmayer | EQ | Common Stock | Options Exercise | 166.6% | 152,361 | 243,805 | 09 Mar 2026 | Direct | ||
| Christine Zedelmayer | EQ | Employee Stock Option (right to buy) | Options Exercise | -100% | -152,361 | 0 | 09 Mar 2026 | Direct | ||
| Christine Zedelmayer | EQ | Common Stock | Sale | -67% | $328,104 | $1.76 | -185,937 | 91,444 | 19 Feb 2026 | Direct |
| Christine Zedelmayer | EQ | Common Stock | Options Exercise | 1249.4% | 185,937 | 200,819 | 19 Feb 2026 | Direct | ||
| Penny Tom | EQ | Common Stock | Sale | -100% | $8,428 | $1.29 | -6,533 | 0 | 08 Jan 2026 | Direct |
| Stephen Connelly | EQ | Employee Stock Option (right to buy) | Award | 1,150,000 | 1,150,000 | 07 Jan 2026 | Direct | |||
| Christine Zedelmayer | EQ | Employee Stock Option (right to buy) | Award | 500,000 | 500,000 | 07 Jan 2026 | Direct | |||
| Bruce D. Steel | EQ | Employee Stock Option (right to buy) | Award | 1,750,000 | 1,750,000 | 07 Jan 2026 | Direct | |||
| Penny Tom | EQ | Employee Stock Option (right to buy) | Award | 450,000 | 450,000 | 07 Jan 2026 | Direct | |||
| Christine Zedelmayer | EQ | Common Stock | Sale | -52.2% | $150,000 | $1.50 | -100,000 | 91,444 | 23 Dec 2025 | Direct |
| Christine Zedelmayer | EQ | Common Stock | Options Exercise | 109.4% | 100,000 | 191,444 | 23 Dec 2025 | Direct | ||
| Christine Zedelmayer | EQ | Employee Stock Option (right to buy) | Options Exercise | -100% | -100,000 | 0 | 23 Dec 2025 | Direct | ||
| Christine Zedelmayer | EQ | Common Stock | Sale | -11.5% | $15,589 | $1.31 | -11,900 | 91,444 | 15 Dec 2025 | Direct |
| Christine Zedelmayer | EQ | Common Stock | Sale | -18.7% | $31,897 | $1.34 | -23,804 | 103,344 | 12 Dec 2025 | Direct |
| Christine Zedelmayer | EQ | Common Stock | Sale | -5.99% | $7,696 | $0.9504 | -8,098 | 127,148 | 25 Nov 2025 | Direct |
| Stephen Connelly | EQ | Employee Stock Option (right to buy) | Award | 1,025,000 | 1,025,000 | 29 Aug 2025 | Direct | |||
| Penny Tom | EQ | Employee Stock Option (right to buy) | Award | 525,000 | 525,000 | 29 Aug 2025 | Direct | |||
| Christine Zedelmayer | EQ | Employee Stock Option (right to buy) | Award | 725,000 | 725,000 | 29 Aug 2025 | Direct | |||
| Bruce D. Steel | EQ | Employee Stock Option (right to buy) | Award | 1,695,000 | 1,695,000 | 29 Aug 2025 | Direct |